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Showing 1-30 of 92 results for "P6001" within Papers
Mabel Lum et al.
Pathogens and disease, 72(3), 174-187 (2014-07-06)
A key feature of Shigella pathogenesis is the ability to spread from cell-to-cell post-invasion. This is dependent on the bacteria's ability to initiate de novo F-actin tail polymerisation, followed by protrusion formation, uptake of bacteria-containing protrusion and finally, lysis of
Chemical leukoderma from hair dye containing para-phenylenediamine.
Terry T Farsani et al.
Dermatitis : contact, atopic, occupational, drug, 23(4), 181-182 (2012-07-26)
Ioannis Sotiropoulos et al.
Experimental neurology, 261, 486-493 (2014-08-01)
Tau protein hyperphosphorylation and consequent malfunction are hallmarks of Alzheimer's disease pathology; importantly, pain perception is diminished in these patients. In physiological conditions, Tau contributes to cytoskeletal dynamics and in this way, influences a number of cellular mechanisms including axonal
Kaori Kojima et al.
Neuroscience letters, 581, 37-41 (2014-08-26)
p62, which is also called sequestosome 1 (SQSTM1), plays a critical role in neuronal cell death. However, the role of p62 in axonal degeneration remains unclear. We evaluated whether the modulation of p62 expression may affect axonal loss in tumor
Yulia Vasianovich et al.
eLife, 9 (2020-10-24)
The templating RNA is the core of the telomerase reverse transcriptase. In Saccharomyces cerevisiae, the complex life cycle and maturation of telomerase includes a cytoplasmic stage. However, timing and reason for this cytoplasmic passage are poorly understood. Here, we use
Ryan J Lopez et al.
Bioelectrochemistry (Amsterdam, Netherlands), 105, 78-87 (2015-05-27)
Pyrroloquinoline quinone dependent soluble glucose dehydrogenase (PQQ-sGDH) enzymatic MWCNT electrodes were p roduced using 1-pyrenecarboxylic acid (PCA) activated through carbodiimide functionalization and 1-Pyrenebutyric acid N-hydroxysuccinimide ester (PBSE) as tethering agents. At 600 mV potential, the current density generated by the
Identification and quantification of para-phenylenediamine in a temporary black henna tattoo
Brancaccio RR, et al.
American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society, 13(1), 15-18 (2002)
p-Phenylenediamine allergy: the role of Bandrowski's base
White JML, et al.
Clinical and Experimental Allergy, 36(10), 1289-1293 (2006)
In vitro evaluation of the sensitization potential of weak contact allergens using Langerhans-like dendritic cells and autologous T cells
Rougier N, et al.
Toxicology, 145(1), 73-82 (2000)
Negar Afshar et al.
eLife, 10 (2021-01-26)
Homologous recombination (HR) is essential for maintaining genome stability. Although Rad51 is the key protein that drives HR, multiple auxiliary factors interact with Rad51 to potentiate its activity. Here, we present an interdisciplinary characterization of the interactions between Rad51 and
Giovanni Rizzo et al.
PloS one, 7(11), e50230-e50230 (2012-12-05)
Leber's hereditary optic neuropathy (LHON) is characterized by retinal ganglion cell (RGC) degeneration with the preferential involvement of those forming the papillomacular bundle. The optic nerve is considered the main pathological target for LHON. Our aim was to investigate the
Alejandra Bosco et al.
Disease models & mechanisms, 8(5), 443-455 (2015-03-11)
Microglia serve key homeostatic roles, and respond to neuronal perturbation and decline with a high spatiotemporal resolution. The course of all chronic CNS pathologies is thus paralleled by local microgliosis and microglia activation, which begin at early stages of the
Christopher L Cunningham et al.
Neuron, 107(1), 126-143 (2020-04-29)
TMC1 and TMC2 (TMC1/2) have been proposed to form the pore of the mechanotransduction channel of cochlear hair cells. Here, we show that TMC1/2 cannot form mechanotransduction channels in cochlear hair cells without TMIE. TMIE binds to TMC1/2, and a
Unusual localization of allergic contact dermatitis from p-phenylenediamine.
Andrea Bassi et al.
Dermatitis : contact, atopic, occupational, drug, 22(6), 358-358 (2012-06-02)
Yanala Sandeep Reddy et al.
Renal failure, 34(7), 880-884 (2012-06-12)
We studied paraphenylenediamine (PPD)-related acute kidney injury (AKI) in 81 patients and also in albino rats experimentally. In the patients' group AKI was found in 32.7%. Of them, 81.4% needed dialysis support. The overall mortality was 25.9%. In experimental rats
Bram Baert et al.
Bioorganic & medicinal chemistry, 15(22), 6943-6955 (2007-09-11)
A set of 116 structurally very diverse compounds, mainly drugs, was characterized by 1630 molecular descriptors. The biological property modelled in this study was the transdermal permeability coefficient logK(p). The main objective was to find a limited set of suitable
York Rudhard et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(7), 2927-2941 (2015-02-24)
Axon degeneration is a programed process that takes place during development, in response to neuronal injury, and as a component of neurodegenerative disease pathology, yet the molecular mechanisms that drive this process remain poorly defined. In this study, we have
Manuj Kr Bharali et al.
Bulletin of environmental contamination and toxicology, 89(4), 712-717 (2012-08-14)
The aim of the present study was to analyze the hematological profile of male SD rats treated topically with aqueous solution of para-phenylenediamine (PPD), a component of almost all hair dye formulations. The rats were painted with different concentration of
Sanjeev Handa et al.
Indian journal of dermatology, venereology and leprology, 78(5), 583-590 (2012-09-11)
Exposure to hair dyes has long been known as a significant risk factor for development of allergic contact dermatitis among the exposed population as these lead to severe eczema of face and upper trunk in the consumer and hand eczema
Mabel Lum et al.
International journal of medical microbiology : IJMM, 304(5-6), 530-541 (2014-04-24)
Shigella infection in epithelial cells induces cell death which is accompanied by mitochondrial dysfunction. In this study the role of the mitochondrial fission protein, Drp1 during Shigella infection in HeLa cells was examined. Significant lactate dehydrogenase (LDH) release was detected
Anna R Moore et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(37), E3919-E3928 (2014-09-10)
Before the human cortex is able to process sensory information, young postmitotic neurons must maintain occasional bursts of action-potential firing to attract and keep synaptic contacts, to drive gene expression, and to transition to mature membrane properties. Before birth, human
Ozge Cemiloglu Ulker et al.
Journal of immunotoxicology, 10(1), 1-8 (2012-06-28)
The present study sought to verify the utility of the non-radioactive endpoints LLNA BrdU (5-bromo-2'-deoxyuridine) ex vivo incorporation and cytokine release using auricular lymph node cells isolated from BALB/c mice topically treated with a strong (formaldehyde or p-phenylene-diamine [PPD]), moderate
Shao-Chih Chiu et al.
American journal of physiology. Cell physiology, 307(5), C466-C478 (2014-07-11)
Cells display dramatic morphological changes in mitosis, where numerous factors form regulatory networks to orchestrate the complicated process, resulting in extreme fidelity of the segregation of duplicated chromosomes into two daughter cells. Astrin regulates several aspects of mitosis, such as
Feng Guo et al.
PloS one, 9(10), e109267-e109267 (2014-10-11)
Repetitive transcranial magnetic stimulation (rTMS) has increasingly been studied over the past decade to determine whether it has a therapeutic benefit on focal cerebral ischemia. However, the underlying mechanism of rTMS in this process remains unclear. In the current study
Methods in Enzymology, 24, 161-161 (1972)
Sharon A Williams et al.
Molecular cancer, 9, 250-250 (2010-09-21)
A growing body of work implicates chemokines, in particular CXCL12 and its receptors, in the progression and site-specific metastasis of various cancers, including breast cancer. Various agents have been used to block the CXCL12-CXCR4 interaction as a means of inhibiting
Thomas Milinkovitch et al.
Aquatic toxicology (Amsterdam, Netherlands), 161, 170-175 (2015-02-24)
Although the variegated scallop Mimachlamys varia seems to be a suitable sentinel species for contaminant monitoring, no study has identified biomarkers in this species. In order to fill this gap, this study conducted an in situ biomarker approach. M. varia
S C Chaudhary et al.
Nigerian journal of clinical practice, 16(2), 258-259 (2013-04-09)
Hair dye containing paraphenylenediamine (PPD) is widely used in India because of its free availability and low cost. PPD produces local as well as systemic toxic effects when applied topically and/or ingested. It is highly toxic when taken by mouth
John Manwaring et al.
Toxicology and applied pharmacology, 287(2), 139-148 (2015-06-02)
Approaches to assess the role of absorption, metabolism and excretion of cosmetic ingredients that are based on the integration of different in vitro data are important for their safety assessment, specifically as it offers an opportunity to refine that safety
Irritant contact dermatitis from a black henna tattoo without sensitization to para-phenylendiamine.
Fabiola Kind et al.
Pediatrics, 131(6), e1974-e1976 (2013-05-22)
Allergic contact dermatitis from nonpermanent black henna tattoos has been frequently reported, particularly in children. Contamination or adulteration of the dyes with para-phenylendiamine has been identified as major cause of active sensitization and elicitation of severe allergic contact dermatitis. Sequelae
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