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Showing 1-27 of 27 results for "P73404" within Papers
Michiko Kimoto et al.
Nucleic acids symposium series (2004), (53)(53), 73-74 (2009-09-15)
The creation of an extra, unnatural base pair that functions in replication, transcription, and translation, would provide a new system for the expansion of the genetic alphabet. In transcription, an unnatural base pair system could be used for making new
Z H Chohan et al.
Chemical & pharmaceutical bulletin, 40(9), 2555-2556 (1992-09-01)
A new Schiff-base ligand N-(2'-pyrrylmethylidene)2-aminopyrimidine derived from the reaction of 2-amino pyrimidine and pyrrol-2-carboxaldehyde and its nickel(II), copper(II) and zinc(II) complexes have been synthesised and characterised on the basis of elemental analysis, molar conductance, infrared, electronic and proton nuclear magnetic
Ichiro Hirao et al.
Nucleic acids symposium series (2004), (49)(49), 33-34 (2006-12-08)
Specific transcription mediated by unnatural base pairs could create novel RNA molecules with increased functionality and expand the genetic code. Here, we report an unnatural base pair between pyrrole-2-carbaldehyde (Pa) and 2-amino-6-(2-thienyl)purine (s) or 6-(2-thienyl)purine (s') for the site-specific incorporation
Clemens Kanzler et al.
Journal of agricultural and food chemistry, 68(1), 332-339 (2019-12-10)
Thermal treatment of food leads to the formation of melanoidins by reactions of carbohydrates with free amino acids or proteins in the late stage of Maillard reaction. The aim of this study was the identification of reaction mechanisms responsible for
Jacques Gros et al.
Journal of agricultural and food chemistry, 65(5), 1058-1069 (2017-01-10)
Chardonnay wines impart a unique complex aroma characterized by its buttery, yellow stone fruit, melon, bready, and woody notes. Among the terms used in the sensory analysis of these wines, this study investigated hazelnut-like attributes. Multidimensional gas chromatography coupled to
Nobuyuki Morohashi et al.
Molecules (Basel, Switzerland), 17(3), 2855-2876 (2012-03-09)
Toward the expansion of the genetic alphabet, an unnatural base pair between 7-(2-thienyl)imidazo[4,5-b]pyridine (Ds) and pyrrole-2-carbaldehyde (Pa) functions as a third base pair in replication and transcription, and provides a useful tool for the site-specific, enzymatic incorporation of functional components
Kyungsil Yoon et al.
Cells, 8(3) (2019-03-15)
Chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is an orphan receptor and member of the nuclear receptor superfamily. Among a series of methylene substituted diindolylmethanes (C-DIMs) containing substituted phenyl and heteroaromatic groups, we identified 1,1-bis(3'-indolyl)-1-(4-pyridyl)-methane (DIM-C-Pyr-4) as an activator of
Huajian Zhu et al.
Organic letters, 13(10), 2792-2794 (2011-04-23)
A new synthetic protocol for efficient and regiospecifc assembly of indolizines and pyrido[1,2-a]indoles by coupling of substituted methyl bromides and alkynes with corresponding pyrrole-2-carboxaldehyde and 1H-indole-2-carboxaldehyde has been developed. Additionally, a possible mechanism for the reaction is proposed.
Diana Rogacz et al.
Molecules (Basel, Switzerland), 23(12) (2018-12-06)
Background: The aim of this work was to evaluate phytotoxicity of the thiophene derivatives against three persistent weeds of a high degree of resistance (Galinsogaparviflora Cav.,Rumexacetosa L., and Chenopodiumalbum) as well as their ecotoxicological impact on Heterocypris incongruens. In addition
Ola Lasekan et al.
BMC chemistry, 13(1), 133-133 (2020-01-01)
The aroma chemistry and the contribution of the aroma compounds to the anti-oxidative properties of roasted yam have yet to be characterized. The growing popularity of roasted yam in regions where they are being consumed calls for a concerted effort
Tsuneo Mitsui et al.
Journal of the American Chemical Society, 125(18), 5298-5307 (2003-05-02)
An unnatural hydrophobic base, pyrrole-2-carbaldehyde (denoted as Pa), was developed as a specific pairing partner of 9-methylimidazo[(4,5)-b]pyridine (Q). The Q base is known to pair with 2,4-difluorotoluene (F) as an isostere of the A-T pair, and F also pairs with
Ping Yan et al.
The Journal of organic chemistry, 73(17), 6587-6594 (2008-07-31)
There is a growing need for cellular imaging with fluorescent probes that emit at longer wavelengths to minimize the effects of absorption, autofluorescence, and scattering from biological tissue. In this paper a series of new environmentally sensitive hemicyanine dyes featuring
Ichiro Hirao et al.
Nucleic acids symposium series (2004), (50)(50), 33-34 (2006-12-08)
The development of unnatural base pairs that function in replication, transcription, and translation could expand the genetic alphabet and enable the site-specific incorporation of functional components into nucleic acids and proteins. We present an unnatural base pair between 7-(2-thienyl)-imidazo[4,5-b]pyridine (denoted
Michiko Kimoto et al.
Nucleic acids research, 35(16), 5360-5369 (2007-08-19)
Fluorescent labeling of nucleic acids is widely used in basic research and medical applications. We describe the efficient site-specific incorporation of a fluorescent base analog, 2-amino-6-(2-thienyl)purine (s), into RNA by transcription mediated by an unnatural base pair between s and
Synthesis, characterization and biological studies of Schiff bases derived from heterocyclic moiety.
Angamaly Antony Shanty et al.
Bioorganic chemistry, 70, 67-73 (2016-11-30)
Some new Schiff bases (H
Yasushi Hikida et al.
Nature protocols, 5(7), 1312-1323 (2010-07-03)
Methods for fluorescent probing at a defined position of RNA provide powerful tools for analyzing the local structural conformation of functional RNA molecules by tracking fluorescence changes. In this article, we describe the site-specific fluorescent probing of RNA by transcription
Adimulam Harinath et al.
Dalton transactions (Cambridge, England : 2003), 47(36), 12613-12622 (2018-07-26)
We report here reactions between the N-adamantyliminopyrolyl ligand 2-(AdN[double bond, length as m-dash]CH)-C4H3NH (L-H) and alkali metal hexamethyldisilazides [MN(SiMe3)2] (M = Li, Na and K) to afford the dimeric [{2-(AdN[double bond, length as m-dash]CH)-C4H3NLi(THF)}2] (1), [{2-(AdN[double bond, length as m-dash]CH)-C4H3N}{Na(THF)1.5}2]
Supojjanee Sansook et al.
Organic & biomolecular chemistry, 15(40), 8655-8660 (2017-10-07)
A series of 3-methylidene-1H-indol-2(3H)-ones substituted with a 5- or 6-pentafluorosulfanyl group has been synthesized by a Knoevenagel condensation reaction of SF
Bibhesh K Singh et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 76(3-4), 376-383 (2010-04-27)
A new Schiff base 2-aminophenol-pyrrole-2-carboxaldehyde and its Zn(II), Cd(II), Sn(II) and Pb(II) complexes have been synthesized and characterized by various physicochemical studies. Spectral studies (IR and (1)H NMR) indicate deprotonation and coordination of phenolic oxygen along with binding of pyrrole
Takumi Ishizuka et al.
Chemical communications (Cambridge, England), 48(88), 10835-10837 (2012-10-04)
Toward new biotechnology by genetic alphabet expansion, we developed an efficient site-specific labeling method for large RNA molecules. The combination of unnatural base pair transcription and post-transcriptional modification by click chemistry enables simple RNA labeling with a wide variety of
Corey A Rice et al.
The Journal of chemical physics, 126(13), 134313-134313 (2007-04-14)
Intermolecular interactions relevant for antiparallel beta-sheet formation between peptide strands are studied by Fourier transform infrared spectroscopy of the low temperature, vacuum-isolated model compound pyrrole-2-carboxaldehyde and its dimer in the N-H and C=O stretching range. Comparison to quantum chemical predictions
Keisuke Kagami et al.
Nutrition (Burbank, Los Angeles County, Calif.), 24(11-12), 1159-1166 (2008-07-01)
Although the chemistry of Maillard reaction products (MRPs) in foods has been well studied, few reports on the nutritional characteristics of MRPs in experimental animals and humans have been found. In this study, our interest was focused on the volatile
Youngwon Kim et al.
Journal of inorganic biochemistry, 205, 111015-111015 (2020-02-08)
A pyrrolyl-iminophosphine (PNNH) which would act as a potential terdentate ligand has been prepared by Schiff base reaction. Complexes [M(PNN)X] (M = Ni; X = Cl (1), Pd; X = Cl (2), Br (3), I (4), M = Pt; X = Cl (5)) were prepared. The title complexes were characterized
Barbara Michela Giuliano et al.
The journal of physical chemistry. A, 114(7), 2506-2517 (2010-01-30)
Monomeric pyrrole-2-carbaldehyde (P2C) was isolated in low-temperature argon and xenon matrices, and its UV-induced photochemistry was studied. The structures of the reagent as well as the reaction photoproducts were characterized by FTIR spectroscopy. Interpretation of the experimental results was assisted
G C Yen et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 24(12), 1303-1308 (1986-12-01)
Three 2-substituted pyrroles (2-acetylpyrrole, pyrrole-2-carboxaldehyde and pyrrole-2-carboxylic acid), which are products of the Maillard browning reaction, were reacted with nitrite in buffer solution (pH 3) at 50 degrees C for 24 hr. The reaction mixtures were extracted with methylene chloride
Aaron R Coffin et al.
The Journal of organic chemistry, 71(17), 6678-6681 (2006-08-12)
A regiocontrolled synthesis of 3,4-disubstituted pyrrole-2-carboxaldehydes was completed in two steps from acyclic starting materials. A Barton-Zard pyrrole synthesis between N-methoxy-N-methyl-2-isocyanoacetamide and alpha-nitroalkenes or beta-nitroacetates provided N-methoxy-N-methyl pyrrole-2-carboxamides (pyrrole Weinreb amides), which were converted into the corresponding pyrrole-2-carboxaldehydes by treatment
Ryuya Fukunaga et al.
Biochemical and biophysical research communications, 372(3), 480-485 (2008-05-28)
An unnatural base pair between 7-(2-thienyl)-imidazo[4,5-b]pyridine (Ds) and pyrrole-2-carbaldehyde (Pa) could expand the genetic alphabet and allow the incorporation of non-standard amino acids into proteins at defined positions. For this purpose, we synthesized tRNAs bearing Pa at the anticodon and
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