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Showing 31-60 of 108 results for "P8765" within Papers
Zhe Zhao et al.
Behavioural brain research, 238, 44-47 (2012-10-24)
Matrix metalloproteinase-9 (MMP-9) has been found at significantly increased activity and also contributes to blood-brain barrier degradation in diabetes. Activation of NF-κB pathway is associated with diabetes-induced cognitive impairment, and MMP-9 gene promoter contains a highly conserved motif that matches
Roberta Baetta et al.
Vascular pharmacology, 67-69, 38-47 (2015-04-08)
The long pentraxin PTX3 is an acute-phase multi-functional protein that might play both positive and detrimental effects under different pathophysiological conditions. We previously showed that statins down-regulate the release of PTX3 in human endothelial cells (ECs). The present study investigated
Wei Shao et al.
The Journal of biological chemistry, 295(52), 18284-18300 (2020-10-29)
Oxygen regulates hypoxia-inducible factor (HIF) transcription factors to control cell metabolism, erythrogenesis, and angiogenesis. Whereas much has been elucidated about how oxygen regulates HIF, whether lipids affect HIF activity is un-known. Here, using cultured cells and two animal models, we
Venugopal Reddy Venna et al.
Acta neuropathologica, 124(3), 425-438 (2012-05-09)
Social isolation (SI) is increasingly recognized as a risk factor for stroke. Individuals with lack of social support systems have an increased incidence of stroke, poorer recovery, and greater functional decline after injury compared to individuals with social support. Attesting
Rijun Gui et al.
Talanta, 94, 257-262 (2012-05-23)
A near-infrared-emitting CdTe/CdS core/shell quantum dots (QDs)-based photoluminescence (PL) sensor was designed and applied for highly selective and sensitive detection of Cd(2+). This sensor was based on a PL "OFF-ON" mode. First, the addition of ammonium pyrrolidine dithiocarbamate (APDC) led
Induction of apoptosis by pyrrolidinedithiocarbamate and N-acetylcysteine in vascular smooth muscle cells
Tsai JC, et al.
The Journal of Biological Chemistry, 271(7), 3667-3670 (1996)
Ling-Xing Li et al.
Cell biology international, 37(9), 988-994 (2013-05-10)
The mechanism of the regulatory roles of stromal cell derived factor-1 (SDF-1)/C-X-C motif receptor 4 (CXCR4) on cell proliferation and apoptosis in vascular smooth muscle cells (VSMCs) via the protein kinase C (PKC) and nuclear factor-kappa B (NF-κB) signalling pathways
Masood Shokri et al.
Analytica chimica acta, 889, 123-129 (2015-09-08)
For the first time, a simple and efficient in situ emulsification microextraction method using a dicationic ionic liquid followed by magnetic assisted physisorption was presented to determine trace amounts of lead. In this method, 400 μL of 1.0 mol L(-1)
Kun-Tsan Lee et al.
Aging, 13(18), 22490-22501 (2021-09-25)
The progression of osteoarthritis (OA) is mediated by adipokines, one of which is nesfatin-1, which is responsible for the production of inflammatory cytokines. However, how this molecule may affect the synthesis of the proinflammatory cytokine interleukin 1 beta (IL-1β) in
Hongli Li et al.
Molecular medicine reports, 6(4), 774-778 (2012-07-31)
Matrix metalloproteinases (MMPs) are critical to vascular smooth muscle cell migration in vivo. The dysregulation of MMPs is involved in the pathogenesis of abnormal arterial remodeling, aneurysm formation and atherosclerotic plaque instability. It has been confirmed that lipopolysaccharides (LPS) constitute
Anti-inflammatory effects of Siegesbeckia orientalis ethanol extract in in vitro and in vivo models.
Yong-Han Hong et al.
BioMed research international, 2014, 329712-329712 (2014-10-21)
This study aims to investigate the anti-inflammatory responses and mechanisms of Siegesbeckia orientalis ethanol extract (SOE). In cell culture experiments, RAW264.7 cells were pretreated with SOE and stimulated with lipopolysaccharide (LPS) for inflammatory mediators assay. In animal experiments, mice were
Denis Nchang Che et al.
International immunopharmacology, 83, 106403-106403 (2020-03-21)
IL-31 and IL-33 are cytokines, which are expressed in many inflammatory and pathological disorders, thus suggesting an IL-31/IL-33 axis interaction in pathological diseases. Luteolin from natural products is known for its anti-inflammatory activities associated with the regulation of inflammatory signaling
Avik Roy et al.
PloS one, 9(7), e101883-e101883 (2014-07-10)
Increase of the density of dendritic spines and enhancement of synaptic transmission through ionotropic glutamate receptors are important events, leading to synaptic plasticity and eventually hippocampus-dependent spatial learning and memory formation. Here we have undertaken an innovative approach to upregulate
Multi-element preconcentration of heavy metal ions from aqueous solution by APDC impregnated activated carbon
Daorattanachai P, et al.
Talanta, 67(1), 59-64 (2005)
Qiaozhuan Li et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 29(3-4), 361-372 (2012-04-18)
To investigate the role and mechanism of PARG inhibition of metastatic behavior in colonic carcinoma cells. We examined the effects of PARG protein knockdown by RNA interference on invasion, migration and matrix adhesion of colon carcinoma cell lines in vitro
Qiaoying Lv et al.
Cancer letters, 442, 137-147 (2018-11-14)
Continuous estrogen signaling is thought to be the main mechanism causing endometrial cancer (EC). Studies have demonstrated that CD163+ macrophages could promote the development of estrogen-dependent EC, but the mechanisms involved remain unclear. We found that CD163+ macrophages were the
Qing Tu et al.
Drug design, development and therapy, 15, 289-303 (2021-02-04)
Severe inflammatory response leads to poor prognosis of acute lung injury (ALI), the role of gypenosides (GPs) on ALI is not fully clear. The study aimed at investigating the effects of GPs on ALI. We firstly established LPS-induced ALI mice
Kimihiro Kimura et al.
Life sciences, 91(13-14), 644-650 (2012-05-10)
It has been reported that endothelin-1 (ET-1) overproduction and reduced nitric oxide (NO) production are closely related to the progression of renal diseases. In the present study, we examined the interrelation between ET-1 and NO system using rats treated with
Gonzalo Alba et al.
The Journal of endocrinology, 214(3), 399-408 (2012-06-29)
Calcineurin (protein phosphatase 2B) (CN) comprises a family of serine/threonine phosphatases that play a pivotal role in signal transduction cascades in a variety of cells, including neutrophils. Angiotensin II (Ang II) increases both activity and de novo synthesis of CN
Seung-Hwan Kwon et al.
Neurochemistry international, 74, 53-64 (2014-05-08)
Sulfuretin, a potent anti-oxidant, has been thought to provide health benefits by decreasing the risk of oxidative stress-related diseases. In this study, we investigated the mechanisms of sulfuretin protection of neuronal cells from cell death induced by the Parkinson's disease
Mirjam Wagner et al.
Journal of cell science, 136(21) (2023-10-10)
Connections between the nucleus and the cytoskeleton are important for positioning and division of the nucleus. In most eukaryotes, the linker of nucleoskeleton and cytoskeleton (LINC) complex spans the outer and inner nuclear membranes and connects the nucleus to the
Sibel Tunali Akar et al.
Journal of hazardous materials, 227-228, 107-117 (2012-06-08)
The biosorption properties of APDC modified S. albus were tested in batch and column conditions. Effective experimental parameters such as pH, biosorbent dosage, contact time, temperature, initial lead(II) ion concentration, flow rate and bed height were investigated. The biosorption capacity
Balakrishnan Umesh et al.
Poultry science, 94(11), 2805-2815 (2015-10-27)
An improved method for the chromatographic separation and determination of chromium (III) and (VI) [ CRIII AND CRVI: ] in mineral mixtures and feed samples has been developed. The method uses precolumn derivatization using ammonium pyrrolidinedithiocarbamate ( APD: ) followed
An NF-kappaB-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells
Lukiw WJ, et al.
The Journal of Biological Chemistry, 283(46), 31315-31322 (2008)
Rajakrishnan Veluthakal et al.
Diabetes, 70(4), 889-902 (2021-02-03)
Enrichment of human islets with syntaxin 4 (STX4) improves functional β-cell mass through a nuclear factor-κB (NF-κB)-dependent mechanism. However, the detailed mechanisms underlying the protective effect of STX4 are unknown. For determination of the signaling events linking STX4 enrichment and
Rui Zhang et al.
International journal of molecular medicine, 46(1), 331-339 (2020-04-23)
Astragalus polysaccharides (APS), the active ingredients isolated from the plant Astragalus, have been reported to have numerous biological activities, including anti‑inflammatory and antitumor activities. However, the effect of APS on pulmonary fibrosis (PF) remains unknown. The present study aimed to evaluate
Yu-Long Sun et al.
Peptides, 47, 124-132 (2013-07-17)
Neuropeptide FF (NPFF) has many functions in regulating various biological processes. However, little attention has been focused on the anti-inflammatory effect of this peptide. In the present study, the in vitro anti-inflammatory activity of NPFF in both primary peritoneal macrophages
Hao-Nan Li et al.
Journal of neuroinflammation, 18(1), 150-150 (2021-07-07)
Our recent studies have identified that the red nucleus (RN) dual-directionally modulates the development and maintenance of mononeuropathic pain through secreting proinflammatory and anti-inflammatory cytokines. Here, we further explored the action of red nucleus IL-33 in the early development of
Ye Wang et al.
Neuroscience letters, 535, 128-133 (2013-01-19)
Cardiac sympathetic hyperinnervation after myocardial infarction (MI) is associated with a high incidence of lethal arrhythmia. However, the mechanisms of nerve sprouting induced by MI are unclear. In this study, we showed a nuclear factor-κB (NF-κB) signaling pathway involved in
Hongxue Wu et al.
Biochemical and biophysical research communications, 514(3), 933-939 (2019-05-16)
Cancer-associated fibroblasts comprise the major stromal cell populations in gastric cancer, which is a significant contributor to cancer-related death worldwide. As a member of the serine protease family, HTRA1 is reportedly involved in malignant transformation of various tumor types. In
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