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Showing 31-60 of 86 results for "phr1075" within Papers
Swathi Kaliki et al.
JAMA ophthalmology, 131(5), 585-593 (2013-03-30)
Conjunctival papilloma is a benign epithelial tumor occurring in both children and adults with varying clinical features and outcomes. In this article, we describe our experience regarding the difference in the clinical features and outcomes of conjunctival papilloma based on
Victoria M Bajo et al.
The European journal of neuroscience, 40(6), 2922-2940 (2014-06-20)
Cholinergic inputs to the auditory cortex can modulate sensory processing and regulate stimulus-specific plasticity according to the behavioural state of the subject. In order to understand how acetylcholine achieves this, it is essential to elucidate the circuitry by which cholinergic
Martina Kubecova et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 42(5), 439-444 (2011-02-19)
Cimetidine, H(2) receptor antagonists, is commonly prescribed for gastric and duodenal ulcer disease. Additionally, cimetidine has been shown to have anticancer effects. This review describes the mechanism of antitumor action of cimetidine including its ability to interfere with tumor cell
Elenaz Naderkhani et al.
Journal of pharmaceutical sciences, 103(6), 1882-1890 (2014-03-26)
Permeability is a crucial property of orally administered drugs. Therefore, in drug discovery, it is important to employ methods suitable for rapidly and reliably screening the permeability of large numbers of new drug candidates. The phospholipid vesicle-based permeation assay (PVPA)
Flávia L Beltrame et al.
Histology and histopathology, 27(10), 1343-1351 (2012-09-01)
Cimetidine, an H₂ receptor antagonist used for treatment of gastric ulcers, exerts antiandrogenic and antiangiogenic effects. In the testes cimetidine impairs spermatogenesis, Sertoli cells and peritubular tissue, inducing apoptosis in the myoid cells. Regarding the importance of histamine and androgens
Lucy C Stott et al.
Aquatic toxicology (Amsterdam, Netherlands), 159, 127-137 (2014-12-30)
The gill is the principle site of xenobiotic transfer to and from the aqueous environment. To replace, refine or reduce (3Rs) the large numbers of fish used in in vivo uptake studies an effective in vitro screen is required that
Determination of cimetidine, famotidine, and ranitidine hydrochloride in the presence of their sulfoxide derivatives in pure and dosage forms by high-performance thin-layer chromatography and scanning densitometry
Kelani KM, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 85(5), 1015-1020 (2002)
R D Evans et al.
Clinics in podiatric medicine and surgery, 17(2), 371-375 (2000-05-16)
Oral cimetidine for the treatment of verruca continues to be a topic of discussion and controversy. Although its usage has gained popularity because it offers an alternative to conventional topical and surgical verruca therapy, its reported efficacy in managing warts
Y Edrei et al.
British journal of cancer, 107(4), 658-666 (2012-07-19)
The poor prognosis of patients with colorectal-cancer liver metastases (CRLM) and the insufficiency of available treatments have raised the need for alternative curative strategies. We aimed to assess the therapeutic potential of TL-118, a new anti-angiogenic drug combination, for CRLM
Cimetidine.
IARC monographs on the evaluation of carcinogenic risks to humans, 50, 235-263 (1990-01-01)
Catherine H Olson et al.
Journal of biomedical informatics, 51, 60-71 (2014-04-17)
Create an automated algorithm for predicting elderly patients' medication-related risks for readmission and validate it by comparing results with a manual analysis of the same patient population. Outcome and Assessment Information Set (OASIS) and medication data were reused from a
Shuang Wang et al.
Human vaccines & immunotherapeutics, 10(2), 461-468 (2013-11-21)
Nizatidine (NIZ), closely related to Cimetidine, is a histamine H2 receptor inverse agonist used primarily as an anti-acid drug. Recent studies showed that this class of compounds may also modulate immune responses. To evaluate adjuvant effects of NIZ on vaccine
Catarina Dias et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(7), 1177-1180 (2012-07-07)
The purpose of this work was to develop and optimize a simple and suitable method to detect the potential inhibitory effect of drugs and medicines on alcohol dehydrogenase (ADH) activity in order to evaluate the possible interactions between medicines and
Zhuo Wang et al.
Cancer chemotherapy and pharmacology, 74(2), 239-247 (2014-06-01)
We investigated E-selectin expression in mice and rabbits with vinorelbine-induced phlebitis and the effect of cimetidine. To find the relationship between E-selectin expression and vinorelbine-induced phlebitis. Mouse and rabbit model of vinorelbine-induced phlebitis was established by intravenous infusion of vinorelbine.
Thomas H Miller et al.
The Science of the total environment, 511, 153-160 (2014-12-30)
The development, characterisation and application of a new analytical method for multi-residue PPCP determination in the freshwater amphipod, Gammarus pulex are presented. Analysis was performed using pulverised liquid extraction (PuLE), solid phase extraction (SPE) and liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Edilson Dantas da Silva Júnior et al.
Naunyn-Schmiedeberg's archives of pharmacology, 387(8), 719-731 (2014-04-17)
Histamine is an important modulatory agent of the sympathetic neurotransmission, but its exact action on the testicular capsule or rat vas deferens is not fully understood. The present study sought to further investigate the functional effects of histamine on the
Mike De Vrieze et al.
Analytical and bioanalytical chemistry, 406(25), 6179-6188 (2014-08-16)
Over the past decades, several in vitro methods have been tested for their ability to predict drug penetration across the blood-brain barrier. So far, in high-performance liquid chromatography, most attention has been paid to micellar liquid chromatography and immobilized artificial
J E Naschitz et al.
Seminars in arthritis and rheumatism, 21(4), 211-220 (1992-02-01)
The term fasciitis-panniculitis syndrome (FPS) is proposed as a novel compilation encompassing several disorders, common to which is subcutaneous induration caused by cicatrizing fasciitis as well as septal and lobular panniculitis and perimysial fibrosis. Included herein are Shulman's eosinophilic fasciitis
Jun Dong et al.
Medical oncology (Northwood, London, England), 31(8), 95-95 (2014-07-06)
The objective of this study was to assess the clinical efficacy of genetically engineered recombinant human adenovirus type 5 (rhAd5) plus transcatheter arterial chemoembolization in patients with unresectable hepatocellular carcinoma (HCC). Data from two groups of patients with unresectable HCC
M Matossian et al.
International journal of immunopathology and pharmacology, 27(4), 573-583 (2015-01-13)
Pathological acid reflux is a common event in patients afflicted with head and neck squamous cell carcinomas (HNSCCs), known to play a role in HNSCC etiology and contribute to complications after surgery or during radiation and chemotherapy. Antacid medications are
Xiaoyu Niu et al.
Archives of toxicology, 89(1), 107-119 (2014-04-29)
The use of diclofenac (DCF), a nonsteroidal anti-inflammatory drug, is associated with a high prevalence of gastrointestinal side effects. In vivo studies in rodents suggested that reactive metabolites of DCF produced by the liver or the intestine might be responsible
Kan Zhong et al.
Antimicrobial agents and chemotherapy, 58(7), 4153-4161 (2014-05-14)
Morinidazole is a novel 5-nitroimidazole antimicrobial drug that undergoes extensive metabolism in humans via N(+)-glucuronidation (N(+)-glucuronide of S-morinidazole [M8-1] and N(+)-glucuronide of R-morinidazole [M8-2]) and sulfation (sulfate conjugate of morinidazole [M7]). Our objectives were to assess the effects of renal
Christine Brauckmann et al.
Journal of chromatography. A, 1279, 49-57 (2013-01-29)
Cimetidine has been studied as an additive in cancer chemotherapy. It is claimed to reduce the side effects of Cisplatin. This study focuses on possible interactions between Cisplatin and cimetidine on the molecular level. Due to the fact that cimetidine
X Niu et al.
Scandinavian journal of immunology, 77(2), 84-91 (2013-01-10)
We and others have previously shown that both cimetidine (CIM) and levamisole (LMS) enhance humoral and cellular responses to DNA vaccines via different mechanisms. In this study, we investigated the synergistic and additive effects of CIM and LMS on the
Tianxiang Kevin Han et al.
The Journal of pharmacology and experimental therapeutics, 352(3), 519-528 (2015-01-08)
Metformin is the frontline therapy for type II diabetes mellitus. The oral bioavailability of metformin is unexpectedly high, between 40 and 60%, given its hydrophilicity and positive charge at all physiologic pH values. Previous studies in Caco-2 cell monolayers, a
Rozina Kousar et al.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 22(1), 41-45 (2013-03-08)
The objective of this study was to assess the pharmacokinetic behavior of floating hydroxypropylmethylcellulose microparticles loaded with cimetidine (FMC) prepared using the non-solvent addition coacervation technique. Based on the physico-chemical characteristics of three formulations (FMC1, FMC2 and FMC3), FMC2 having
Dipy M Vasa et al.
Journal of pharmaceutical sciences, 103(9), 2911-2923 (2014-05-16)
Fifteen model drugs were quenched from 3:1 (w/w) mixtures with polyethylene glycol 4000 (PEG4000). The resulting solids were characterized using powder X-ray diffraction (PXRD), analysis of pair distribution function-transformed PXRD data (where appropriate), hot-stage polarized light microscopy, and differential scanning
M A Sa'adah et al.
European neurology, 42(1), 23-26 (1999-07-08)
Two cases of optic neuropathy associated with cimetidine therapy are reported. Recovery occurred in both after drug withdrawal. Rechallenge with the same agent totally reproduced the condition in the first case. Cimetidine exerts an unequivocal toxicity on the central and
Ching-Long Lai et al.
Chemico-biological interactions, 202(1-3), 275-282 (2012-12-12)
Previous studies have reported that cimetidine, an H2-receptor antagonist used to treat gastric and duodenal ulcers, can inhibit alcohol dehydrogenases (ADHs) and ethanol metabolism. Human alcohol dehydrogenases and aldehyde dehydrogenases (ALDHs), the principal enzymes responsible for metabolism of ethanol, are
S Koarada et al.
Nihon Jinzo Gakkai shi, 34(11), 1227-1232 (1992-11-01)
Cimetidine is a histamine H2-receptor antagonist. Widely it is prescribed, and then various side effects have been increasingly recognized. Acute renal failure as a result of acute interstitial nephritis is one of the most important adverse effect. We report a
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