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Showing 1-30 of 137 results for "PHR1117" within Papers
Hamid Reza Naijian et al.
Cryobiology, 66(2), 151-155 (2013-01-15)
Oxidative damage to sperm is one of the main causes for decline in motility and fertility of frozen-thawed sperm. Thus, it is crucial to use cryoprotectant agents in extender in order to prevent lethal intracellular ice crystal formation. The present
Emerson Silva Lima et al.
Molecules (Basel, Switzerland), 18(1), 178-189 (2012-12-25)
4-nerolidylcatechol (4-NC) is an unstable natural product that exhibits important antioxidant, anti-inflammatory and other properties. It is readily obtainable on a multi-gram scale through straightforward solvent extraction of the roots of cultivated Piper peltatum or P. umbellatum, followed by column
Rio P Juni et al.
JACC. Basic to translational science, 4(5), 575-591 (2019-11-27)
The positive findings of the EMPA-REG OUTCOME trial (Randomized, Placebo-Controlled Cardiovascular Outcome Trial of Empagliflozin) on heart failure (HF) outcome in patients with type 2 diabetes mellitus suggest a direct effect of empagliflozin on the heart. These patients frequently have
Sheng-Hung Wang et al.
Archives of oral biology, 59(8), 800-807 (2014-05-27)
Plasma levels of polyunsaturated fatty acids (PUFAs) are different before and after periodontal treatment. Asians and Westerners have significantly different baseline levels of plasma PUFAs. However, no Asian study has reported the effects of nonsurgical treatment on the correlation between
Mustapha Lhor et al.
Biochimica et biophysica acta, 1848(3), 878-885 (2014-12-30)
Retinol dehydrogenase 11 (RDH11) has been postulated to be anchored to membranes by means of its N-terminal segment in retinal pigment epithelial (RPE) cells where it participates to the visual cycle. The analysis of the primary sequence of RDH11 revealed
Darine A Salam et al.
Environmental science & technology, 46(12), 6798-6805 (2012-06-12)
Antioxidants added to vegetable oils to prevent lipid oxidation significantly affect their biodegradation in impacted aquatic environments. In this study, the effect of butylated-hydroxytoluene (BHT) on the biodegradation of glyceryl trilinoleate, a model vegetable oil highly susceptible to autoxidation, was
Wageeh A Yehye et al.
Molecules (Basel, Switzerland), 17(7), 7645-7665 (2012-06-27)
A computer-aided predictions of antioxidant activities were performed with the Prediction Activity Spectra of Substances (PASS) program. Antioxidant activity of compounds 1, 3, 4 and 5 were studied using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and lipid peroxidation assays to verify the predictions obtained
G M Williams et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 37(9-10), 1027-1038 (1999-10-29)
Butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) are widely used antioxidant food additives. They have been extensively studied for potential toxicities. This review details experimental studies of genotoxicity and carcinogenicity which bear on cancer hazard assessment of exposure to humans.
Alexander M Firsov et al.
Biochimica et biophysica acta, 1848(3), 767-774 (2014-12-09)
Interaction of cytochrome c with mitochondrial cardiolipin converting this electron transfer protein into peroxidase is accepted to play an essential role in apoptosis. Cytochrome c/cardiolipin peroxidase activity was found here to cause leakage of carboxyfluorescein, sulforhodamine B and 3-kDa (but
Abdulselam Ertas et al.
Pharmaceutical biology, 53(3), 334-339 (2014-10-22)
In Turkey, Veronica species (Plantaginaceae) have been used as a diuretic and for wound healing in traditional medicine. To examine the fatty acid and essential oil profiles, the antioxidant, anticholinesterase, antimicrobial, and DNA damage effects of Veronica thymoides P.H. Davis
E M Bomhard et al.
Mutation research, 277(3), 187-200 (1992-09-01)
Butylated hydroxytoluene (BHT) is an effective, widely used, low cost antioxidant. A host of studies examining the potential of BHT to cause point mutations have been published. They include in vitro studies on various bacterial species and strains and on
Ma Paz Lorenzo et al.
Journal of pharmaceutical and biomedical analysis, 107, 480-487 (2015-02-14)
Gestational Diabetes Mellitus (GDM) is defined as glucose intolerance with onset or first recognition during pregnancy. It is affecting approximately up to 14% of all pregnancies with an increasing tendency. GDM has been related to relevant short-term and long-term health
Natalia Fagali et al.
Biochemical and biophysical research communications, 423(4), 873-877 (2012-06-21)
There is no general agreement yet on the antioxidant effect of pineal indoles against lipid peroxidation. Accordingly, the main goal of the present work was to study the antioxidant activity of melatonin (MLT), N-acetylserotonin (NAS), 5-HO-tryptophan (5HO-TRP) and 5-methoxytryptamine (5MTP)
Wei Liu et al.
Free radical biology & medicine, 47(8), 1101-1107 (2009-08-04)
Free radical-induced lipid peroxidation has been implicated in a number of human diseases including atherosclerosis, cancer, and neurodegenerative diseases. F(2)-Isoprostanes (IsoPs) are isomers of prostaglandin PGF(2alpha) that are generated in vivo from the free radical-initiated peroxidation of arachidonic acid independent
Ge Liu et al.
Prostaglandins, leukotrienes, and essential fatty acids, 91(6), 251-260 (2014-12-03)
Conventional assays of omega-3 long chain polyunsaturated fatty acid (n-3 LCPUFA) status in humans involve venous blood collection and expensive, multi-step processes that limit their usefulness as screening tools. This study aimed to develop a capillary dried blood spot (DBS)
Peng Guo et al.
Nanomedicine (London, England), 8(3), 333-341 (2012-09-05)
The aim of the present study was to develop a simple and straightforward method for formulating hydrophobic drugs into nanoparticulate form in a scalable and inexpensive manner. The nanoporous membrane extrusion (NME) method was used to prepare hydrophobic drug nanoparticles.
Jocelijn Meijerink et al.
British journal of pharmacology, 172(1), 24-37 (2014-05-02)
N-docosahexaenoylethanolamine (DHEA) is the ethanolamine conjugate of the long-chain polyunsaturated n-3 fatty acid docosahexaenoic (DHA; 22: 6n-3). Its concentration in animal tissues and human plasma increases when diets rich in fish or krill oil are consumed. DHEA displays anti-inflammatory properties
Mateus Fortes Rossato et al.
Inflammation, 38(2), 606-615 (2014-08-15)
Vitamin E (vit-E) is a lipophilic antioxidant, and its anti-inflammatory activity is still not full characterized. Thus, our goal was to investigate the anti-inflammatory effect of repeated vit-E treatment in the arthritis induced by the intraplantar injection of complete Freund's
Michael Drechsler et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(3), 807-815 (2014-10-11)
The aim of the present study was to develop film-coated tablets which release a minor amount of the active pharmaceutical ingredient (API) into the stomach and small intestine, yet show a sharp increase of drug release in the colon. Tablets
Mei Yang et al.
Food chemistry, 177, 304-312 (2015-02-11)
It has been claimed that consumptions of Abrus cantoniensis (AC) and Abrus mollis (AM) as folk beverages and soups are good to cleanse liver toxicants and prevent liver diseases. There is scant information on the phytochemical profiles and antioxidant activities
Arjen VanDoorn et al.
BMC plant biology, 10, 164-164 (2010-08-11)
Some plants distinguish mechanical wounding from herbivore attack by recognizing specific constituents of larval oral secretions (OS) which are introduced into plant wounds during feeding. Fatty acid-amino acid conjugates (FACs) are major constituents of Manduca sexta OS and strong elicitors
V T de Lima et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 21(11), 1298-1302 (2014-08-31)
The essential oil from the leaves of Ocimum kilimandscharicum (EOOK), collected in Dourados-MS, was investigated for anticancer, anti-inflammatory and antioxidant activity and chemical composition. The essential oil was extracted by hydrodistillation, and the chemical composition was performed by gas chromatography-mass
J T Sharick et al.
Functional ecology, 29(3), 367-376 (2015-05-20)
The trade-off between current reproductive effort and survival is a key concept of life history theory. A variety of studies support the existence of this trade-off but the underlying physiological mechanisms are not well-understood. Oxidative stress has been proposed as
Rita Ceresole et al.
Journal of cosmetic science, 64(5), 317-328 (2013-10-22)
During preformulation studies of cosmetic/pharmaceutical products, thermal analysis techniques are very useful to detect physical or chemical incompatibilities between the active and the excipients of interest that might interfere with safety and/or efficacy of the final product. Differential scanning calorimetry
Adam H Metherel et al.
The Journal of nutrition, 145(3), 654-660 (2015-03-04)
Fingertip prick whole blood collection on chromatography paper is amenable to high-throughput fatty acid (FA) profiling for large clinical and field studies. However, sample storage is problematic because highly unsaturated FAs (HUFAs) in erythrocytes rapidly degrade in samples stored at
Mohammadali Azadfar et al.
International journal of biological macromolecules, 75, 58-66 (2015-01-21)
The structure of lignin obtained from the ozone and soaking aqueous ammonia pretreatment of wheat straw has been characterized utilizing chemical analytical methods in order to reveal its antioxidant characteristics, including attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), pyrolysis-gas chromatography/mass
Chamila Nimalaratne et al.
Journal of agricultural and food chemistry, 63(11), 2956-2962 (2015-03-10)
Among dietary carotenoids, lutein and zeaxanthin are known to protect against age-related macular degeneration, a leading cause of irreversible vision loss in the elderly. Egg yolk is rich in lutein and zeaxanthin, however, the effect of cooking and gastrointestinal digestion
Butylated hydroxytoluene (BHT): a review.
H Babich
Environmental research, 29(1), 1-29 (1982-10-01)
Matthew R Chin et al.
ACS chemical neuroscience, 6(4), 542-550 (2015-01-24)
The natural product vinaxanthone has demonstrated a remarkable capability to promote nerve growth following injury or transplantation. In rats following total transection of the spinal cord delivery of vinaxanthone enhanced axonal regeneration, remyelination and angiogenesis at the site of injury
Li Cui et al.
Neurobiology of aging, 30(6), 903-909 (2007-11-03)
Aging was associated with increased oxidation of DNA, RNA, and lipids in the cerebellum of male rats. DNA and lipid oxidation was reduced by lifelong (94 weeks) voluntary exercise on a running wheel. A reduction in cerebellar lipid oxidation, but
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