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Showing 1-30 of 34 results for "phr1248" within Papers
Sergey Vyazovkin et al.
Pharmaceutical research, 23(9), 2158-2164 (2006-09-05)
To demonstrate the utility of differential scanning calorimetry (DSC) for determining activation energy landscape in amorphous pharmaceutical systems throughout the sub-Tg and Tg regions. DSC was employed to determine the effective activation energies (E) of the relaxation in sub-Tg and
Tu Liang et al.
Journal of chromatography. A, 1388, 110-118 (2015-03-03)
A diterpene glycoside compound, rebaudioside A (commonly abbreviated as RA), was immobilized onto porous silica surface through "thiol-ene" click chemistry strategy. The successful immobilization of the RA on the silica support was confirmed by FT-IR and elemental analysis. Chromatographic characteristics
S Nakamura et al.
European journal of clinical nutrition, 61(9), 1086-1093 (2007-01-26)
To estimate the suppressive effect of partially hydrolyzed guar gum (PHGG) on transitory diarrhea induced by ingestion of a sufficient amount of maltitol or lactitol in female subjects. The first, the minimal dose level of maltitol and lactitol that would
Determination of maltitol, isomaltitol, and lactitol by high-pH anion-exchange chromatography with pulsed amperometric detection
Cataldi.I.RT, et al.
Journal of Agricultural and Food Chemistry, 47(1), 157-163 (1999)
K K Mäkinen et al.
Calcified tissue international, 44(4), 258-268 (1989-04-01)
Addition of common dietary carbohydrates to Millipore-treated human whole saliva either enhances or inhibits the formation of salivary precipitates, some carbohydrates showing no effect. The purpose of this study was to investigate the precipitation conditions more thoroughly and to elucidate
Yayoi Kawano et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 130(1), 81-86 (2010-01-05)
We investigated several methods of taste masking in the preparation of orally disintegrating tablets (ODTs), using furosemide (FU) as a model drug. Four types of FU preparations were prepared: granules with maltitol (MA), granules with yogurt powder (YO), a physical
J Quílez et al.
Journal of food science, 72(6), S407-S411 (2007-11-13)
The aim of this study was to determine the postprandial glucose (GR), insulin (IR), and triglyceride response as well as the satiety response (SR) to low-calorie muffins (LCMs) and to compare them to those of conventional plain muffins (PMs) and
G Saint-Lorant et al.
International journal of pharmaceutics, 334(1-2), 85-91 (2006-11-23)
The aim of this work is to study carriers which can become alternatives to monohydrate lactose in dry powder inhalers and to consider particle parameters that influence adhesion between drug and carrier in dry powder inhalers. Different forms of mannitol
N A Hall et al.
Analytical biochemistry, 178(2), 378-384 (1989-05-01)
A method for the high-performance liquid chromatography separation of tritium-reduced, acetylated oligosaccharides is described. Their highly sensitive detection in column eluant is facilitated by the use of a flow radioactivity detector. The method differentiates some structural isomers and provides resolution
C Thabuis et al.
European journal of paediatric dentistry : official journal of European Academy of Paediatric Dentistry, 14(4), 303-308 (2013-12-10)
The effects on plaque parameters of sugar free chewing-gums (CG) sweetened with either maltitol or xylitol were assessed to better understand the role polyols can play in dental caries prevention. A double-blind, parallel, randomised, controlled study was conducted in China.
Hirohiko Nakamura et al.
Journal of physiological anthropology, 29(3), 103-108 (2010-06-19)
This study examined the influences of the oral ingestion of casein hydrolysate from bovine milk at rest physiologically and psychologically. Eleven male university students were given a casein hydrolysate drink (H) or a maltitol drink as a control (C) in
Tsuneyuki Oku et al.
Journal of nutritional science and vitaminology, 54(4), 309-314 (2008-09-18)
Using a single-group time-series design, we determined that osmotic diarrhea caused by maltitol ingestion was suppressed by the addition of not only soluble but also insoluble dietary fiber in healthy humans. We then clarified that cellulose delayed gastric emptying in
S Haresaku et al.
Caries research, 41(3), 198-203 (2007-04-12)
Many studies have shown the effects of chewing xylitol gum on mutans streptococci (MS) over short- and long-term periods in children; however, few studies have addressed long-term periods in adults. The objective of this investigation was to examine for 6
Vasso Psimouli et al.
Journal of the science of food and agriculture, 92(1), 99-105 (2011-08-13)
The aim of this research was to investigate whether certain polyols (mannitol, maltitol, sorbitol, lactitol), fructose, oligofructose and polydextrose can replace sugar (by an equal amount of each substitute) in cake formulations. The rheological behaviour of the cake batter and
Pernilla Lif Holgerson et al.
Oral health & preventive dentistry, 5(4), 313-319 (2008-01-05)
The aims were to evaluate a simple method to disclose a microbial shift in saliva and to investigate the short- and long-term effects of daily use of xylitol-containing chewing gums on mutans streptococci (MS) and [14C]-xylitol uptake in saliva. In
Pernilla Lif Holgerson et al.
International journal of paediatric dentistry, 17(2), 79-85 (2007-02-01)
The aim of this study was to investigate the effect of a fixed daily dose of xylitol on mutans streptococci in saliva and the amount of visible dental plaque. A second aim was to explore if the possible effects differed
Aija-Maaria Hietala Lenkkeri et al.
International journal of paediatric dentistry, 22(3), 180-190 (2011-09-29)
Xylitol studies suggest caries reductions in the order of 50%. Based on animal/microbial studies, erythritol potentially has caries-preventive properties. However, clinical studies are required to confirm this. The aim of the study was to investigate the additional caries-preventive effect of
Virgilijus Uloza et al.
Pharmacy world & science : PWS, 32(4), 420-423 (2010-06-05)
To explore the swallowing-enhancing and taste-masking effects of MedCoat, a new disposable device used to apply a coating to tablets just before oral administration. Kaunas Medical University Hospital in Lithuania. The study was performed as a randomized cross-over study. In
Xiaoming Liu et al.
Journal of agricultural and food chemistry, 57(6), 2339-2345 (2009-02-24)
The objective of this study was to investigate the influence of polyols on the stability of whey proteins in an intermediate-moisture food model system and to elucidate the effect of polyols on the hardening of whey protein-based bars during storage.
Simultaneous separation and determination of erythritol, xylitol, sorbitol, mannitol, maltitol, fructose, glucose, sucrose and maltose in food products by high performance liquid chromatography coupled to charged aerosol detector
Grembecka M, et al.
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 117, 77-82 (2014)
Kenta Yamamoto et al.
Chemical & pharmaceutical bulletin, 57(10), 1058-1060 (2009-10-06)
Medicinal carbon (MC) tablets were prepared with several saccharides to improve the formability and absorption ability of MC tablets made with maltitol (MT). The MC tablets were made by the wet granule compression method, in which maltitol, xylitol (XYL), mannitol
Ken-ichi Izutsu et al.
AAPS PharmSciTech, 10(2), 524-529 (2009-05-08)
Near-infrared (NIR) spectroscopic analysis of noncrystalline polyols and saccharides (e.g., glycerol, sorbitol, maltitol, glucose, sucrose, maltose) was performed at different temperatures (30-80 degrees C) to elucidate the effect of glass transition on molecular interaction. Transmission NIR spectra (4,000-12,000 cm(-1)) of
T Oku et al.
Journal of nutritional science and vitaminology, 37(5), 529-544 (1991-10-01)
Six healthy male subjects were given a single oral dose of 0.4 g of maltitol per kg body weight containing [U-14C]-maltitol (50 microCi) and their breath, urine, feces and blood were collected at appropriate intervals for 48 h to measure
A Secchi et al.
Klinische Wochenschrift, 64(6), 265-269 (1986-03-17)
The present study was aimed to investigate the metabolic effects of acute and chronic oral administration of maltitol (4-O-i-D-glucopyranosyl-D-glucitol), a hypocaloric sweetener obtained from maltose by catalytic hydrogenation. Fifty grams of maltitol induced a increase lower glycemic and insulinemic than
Megan Pratt et al.
Nutrition research (New York, N.Y.), 31(3), 223-228 (2011-04-13)
Consumption of a low glycemic index (GI) diet may be helpful in the management and prevention of diabetes and cardiovascular disease. The investigation of GI has been predominantly confined to white subjects. We hypothesized that differences in glycemic response (GR)
Clementine Thabuis et al.
International journal of food sciences and nutrition, 61(7), 728-738 (2010-05-15)
Polyols are molecules of interest for food industries because of their technological and nutritional properties. Maltitol is known for its non-acidogenic and low-energetic properties. Our primary objective was to evaluate the digestive tolerance of maltitol in children. The secondary objective
Emma Beards et al.
The British journal of nutrition, 104(5), 701-708 (2010-04-08)
Sweeteners are being sourced to lower the energetic value of confectionery including chocolates. Some, especially non-digestible carbohydrates, may possess other benefits for human health upon their fermentation by the colonic microbiota. The present study assessed non-digestible carbohydrate sweeteners, selected for
Yayoi Kawano et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 130(1), 75-80 (2010-01-05)
Many orally disintegrating tablets have recently been developed to improve oral ingestion and usability and are widely administered clinically, resulting in improved quality of life for patients. Since orally disintegrating tablets rapidly disintegrate in the mouth, the masking of unpleasant
D Desai et al.
International journal of pharmaceutics, 342(1-2), 87-94 (2007-06-23)
Three guanine-based antiviral drugs, entecavir, lobucavir, and acyclovir showed degradation in presence of sucrose in ready-to-use solutions held at 50 degrees C, with more degradation at pH 4 than at pH 6 or 7. LC/MS analysis of the solutions showed
Vikas A Saharan et al.
Acta pharmaceutica (Zagreb, Croatia), 61(3), 323-334 (2011-09-29)
The poorly water soluble antidiabetic drug gliclazide was selected to study the effect of excipients on dissolution rate enhancement. Ordered mixtures of micronized gliclazide with lactose, mannitol, sorbitol, maltitol and sodium chloride were prepared by manual shaking of glass vials
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