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Showing 1-30 of 131 results for "PHR1279" within Papers
Martin F Pera
Nature genetics, 45(12), 1412-1413 (2013-11-26)
The simple addition of vitamin C to cell culture medium can induce extensive remodeling of the cellular epigenome and facilitates reprogramming of somatic cells to pluripotency. A new study shows that the activity of the enzyme TET1 can inhibit or
A L Althaus et al.
Journal of neurophysiology, 113(4), 1184-1194 (2014-11-28)
Hilar ectopic dentate granule cells (DGCs) are a salient feature of aberrant plasticity in human temporal lobe epilepsy (TLE) and most rodent models of the disease. Recent evidence from rodent TLE models suggests that hilar ectopic DGCs contribute to hyperexcitability
Yan Zhu et al.
Food science and technology international = Ciencia y tecnologia de los alimentos internacional, 19(4), 291-303 (2013-06-05)
Patulin is a mycotoxin produced by a wide range of molds involved in fruit spoilage, most commonly by Penicillium expansum and is a health concern for both consumers and manufacturers. The current study evaluated feasibility of monochromatic ultraviolet (UV) radiation
M Zen Rahfiludin et al.
The Southeast Asian journal of tropical medicine and public health, 44(5), 733-739 (2014-01-21)
Plasmodium vivax infection in humans can relapse and is associated with iron deficiency. The immune response plays an important role in preventing relapse. In this study we analyzed the effect of zinc and vitamin C supplementation on hemoglobin and hematocrit
Claire M White et al.
The Cochrane database of systematic reviews, 12(12), CD008146-CD008146 (2014-12-19)
Persistent feelings of fatigue (or subjective fatigue), which may be experienced in the absence of physiological factors, affect many people with peripheral neuropathy. A variety of interventions for subjective fatigue are available, but little is known about their efficacy or
Usama Ahmed Ali et al.
The Cochrane database of systematic reviews, 8(8), CD008945-CD008945 (2014-08-22)
Reduced intake and absorption of antioxidants due to pain and malabsorption are probable causes of the lower levels of antioxidants observed in patients with chronic pancreatitis (CP). Improving the status of antioxidants might be effective in slowing the disease process
Martin Sillesen et al.
The journal of trauma and acute care surgery, 76(1), 12-19 (2013-12-26)
Traumatic brain injury (TBI) and hemorrhagic shock (HS) can be associated with coagulopathy and inflammation, but the mechanisms are poorly understood. We hypothesized that a combination of TBI and HS would disturb coagulation, damage the endothelium, and activate inflammatory and
Sodium Ascorbate
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 35(6), 4018-4018 (2018)
Bryan M Hooks et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(10), 4418-4426 (2015-03-13)
Cortical cells integrate synaptic input from multiple sources, but how these different inputs are distributed across individual neurons is largely unknown. Differences in input might account for diverse responses in neighboring neurons during behavior. We present a strategy for comparing
Max Leenders et al.
International journal of cancer, 135(12), 2930-2939 (2014-04-29)
Carotenoids and vitamins A, C and E are possibly associated with a reduced colorectal cancer (CRC) risk through antioxidative properties. The association of prediagnostic plasma concentrations and dietary consumption of carotenoids and vitamins A, C and E with the risk
Olivier Fain
La Revue du praticien, 63(8), 1091-1096 (2013-12-05)
Vitamin C is a water soluble vitamin which is mainly fresh fruits and vegetables foodborne. Vitamin C deficiency is most often due to a lack of daily amount. Scurvy is characterized by the occurrence of fatigue, myalgia, arthralgia, purpura, bleeding
Sławomir Tokarski et al.
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 35(207), 136-140 (2013-11-15)
One of the main after-effects of chemotherapy used in cancer treatment is an augmented production of reactive oxygen species (ROS). In turn ROS become a source of unwanted side effects of chemotherapy, often forcing the discontinuation of the therapy. Ascorbic
Feng Xu et al.
Journal of nanoscience and nanotechnology, 13(1), 558-563 (2013-05-08)
In this article, we describe an aptamer-based sandwich-type electrochemical sensor for the detection of human alpha-thrombin. Au nanoneedles were synthesized in the hole of the naked polycarbonate (PC) template using electrodepositing strategy. The thiolated thrombin aptamer I was immobilized as
Christopher M Stephenson et al.
Cancer chemotherapy and pharmacology, 72(1), 139-146 (2013-05-15)
This phase I clinical trial evaluated the safety, tolerability, and pharmacokinetics of high-dose intravenous (i.v.) ascorbic acid as a monotherapy in patients with advanced solid tumors refractory to standard therapy. Five cohorts of three patients received i.v. ascorbic acid administered
Sevnur Serim et al.
Organic & biomolecular chemistry, 13(8), 2293-2299 (2015-01-03)
Activity-based probes (ABPs) are powerful tools for the analysis of active enzyme species in whole proteomes, cells or animals. Quenched fluorescent ABPs (qABPs) can be applied for real time imaging, allowing the visualization of dynamic enzyme activation by fluorescent microscopy.
Beata Jabłonowska-Lietz et al.
Roczniki Panstwowego Zakladu Higieny, 64(1), 43-48 (2013-06-26)
The health benefits arising from antioxidant vitamins A, C and E are well recognised and their recommended dietary intake for the general population have been established. However, there is still a need for assessing antioxidant vitamin intake in different population
J Bautista-Ortega et al.
Poultry science, 93(4), 979-988 (2014-04-08)
The effects of l-Arg, vitamin C (VC), and vitamin E (VE) on xanthine- (XO) and NAD(P)H-oxidase (NOX) activities, and nitric oxide (NO) availability of hypoxic broilers were evaluated. Chickens were kept in wire cages with free access to feed and
Eugenio Jose Garcia et al.
The European journal of esthetic dentistry : official journal of the European Academy of Esthetic Dentistry, 7(2), 154-162 (2012-05-31)
It is generally not recommended that bonded restoration treatment should be carried out immediately after bleaching treatment. However, the use of antioxidants such as sodium ascorbate can be useful to avoid a waiting period. This article is a brief review
Kristina A Simeone et al.
Experimental neurology, 251, 84-90 (2013-11-26)
Mitochondria actively participate in neurotransmission by providing energy (ATP) and maintaining normative concentrations of reactive oxygen species (ROS) in both presynaptic and postsynaptic elements. In human and animal epilepsies, ATP-producing respiratory rates driven by mitochondrial respiratory complex (MRC) I are
FPIN's clinical inquiries. Treatments for symptoms of the common cold.
Cat Livingston et al.
American family physician, 88(12), Online-Online (2013-12-25)
Francisco J Garcia et al.
European journal of medicinal chemistry, 88, 28-33 (2014-06-30)
Reversible oxidation of protein tyrosine phosphatases (PTPs) has emerged as an important regulatory mechanism whereby reactive oxygen species (ROS) inactivates the PTP and promotes phosphorylation and induction of the signaling cascade. The lack of sensitive and robust methods to directly
Adam Drewnowski et al.
The American journal of clinical nutrition, 99(5 Suppl), 1223S-1228S (2014-03-22)
Nutrient profiling is the technique of rating or classifying foods on the basis of their nutritional value. Foods that supply relatively more nutrients than calories are defined as nutrient dense. Nutrient profile models calculate the content of key nutrients per
K E Hwang et al.
Poultry science, 92(12), 3244-3250 (2013-11-16)
We investigated the inhibition of lipid oxidation of raw chicken patties by the antioxidants ascorbic acid (Aa), ganghwayakssuk extracts (GE), and their combination (Aa + GE). All antioxidant combinations were effective at delaying lipid oxidation compared with the control or
Scott B Swarbreck et al.
The Journal of surgical research, 191(2), 432-440 (2014-05-13)
Sepsis, a potential risk associated with surgery, leads to a systemic inflammatory response including the plugging of capillary beds. This plugging may precipitate organ failure and subsequent death. We have shown that capillary plugging can be reversed rapidly within 1
Annlia Paganini-Hill et al.
American journal of epidemiology, 181(2), 120-126 (2015-01-01)
To assess the relationship between antioxidant vitamin intake and all-cause mortality in older adults, we examined these associations using data from the Leisure World Cohort Study, a prospective study of residents of the Leisure World retirement community in Laguna Hills
Junitsu Ito et al.
Life sciences, 95(1), 1-8 (2013-12-21)
Aldehyde reductase (AKR1A), a member of the aldo-keto reductase superfamily, is highly expressed in the liver and is involved in both the detoxification of carbonyl compounds and ascorbic acid biosynthesis. By comparison with wild-type mice, Akr1a-knockout (Akr1a(-/-)) mice and human
David L Choveaux et al.
Experimental parasitology, 148, 30-39 (2014-12-03)
Copper is an essential micronutrient for all living organisms as an important catalytic co-factor for key enzymes. In higher eukaryotes intracellular copper is distributed by copper metallochaperones. Copper chelators such as neocuproine and tetrathiomolybdate inhibit Plasmodium falciparum erythrocytic development, indicating
Sasmita Tripathy et al.
Journal of lipid research, 55(7), 1448-1464 (2014-05-13)
Nonalcoholic fatty liver disease is a major public health concern in the obese and type 2 diabetic populations. The high-fat lard diet induces obesity and fatty liver in C57BL/6J mice and suppresses expression of the PPAR-target gene, FA elongase 5
Uwe Gröber et al.
Medizinische Monatsschrift fur Pharmazeuten, 36(4), 133-143 (2013-05-10)
Many patients receiving cancer treatment use micronutrient supplements, with the intention to complement their cancer treatment, or help them cope with the therapy- and disease-associated side-effects. Up to 90% of the cancer patients are adding antioxidants without the knowledge of
Jiangnan Zheng et al.
Journal of chromatography. A, 1358, 29-38 (2014-07-22)
Selective enrichment of glycopeptides from complex biological samples is essential for MS-based glycoproteomics, but challenges still remain. In this work, glucose-functionalized magnetic mesoporous nanoparticles (MMNs), which hold the attractive features of well-defined core/shell structure, high specific surface area (324m(2)/g), narrow
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