PHR1306

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Showing 1-16 of 16 results for "PHR1306" within Papers

Characterization of sakA gene from pathogenic dimorphic fungus Penicillium marneffei.

Panjaphorn Nimmanee et al.

International journal of medical microbiology : IJMM, 305(1), 65-74 (2014-12-04)

Eukaryotes utilize stress activated protein kinase (SAPK) pathways to adapt to environmental stress, including heat, osmotic, oxidative or nutrient stresses. Penicillium marneffei (Talaromyces marneffei), the dimorphic pathogenic fungus that can cause disseminated mycosis in HIV-infected patients, has to encounter various

Determination of the antioxidant 3-tert.-butyl-4-hydroxyanisole in rat plasma using high-resolution gas chromatography?mass spectrometry

Bailey E, et al.

Journal of Chromatography. B, Biomedical Sciences and Applications, 225(1), 83-89 (1981)

Oxidative stress influences positive strand RNA virus genome synthesis and capping.

Rebekah C Gullberg et al.

Virology, 475, 219-229 (2014-12-17)

Flaviviruses are 5' capped positive-stranded RNA viruses that replicate their genomes within endoplasmic reticulum-derived vesicles. Flaviviruses are well known to induce oxidative stress late in infection but it is unknown if oxidative stress plays a positive role in the viral

Apoptotic effects of platelet factor VIII on megakaryopoiesis: implications for a modified human FVIII for platelet-based gene therapy.

T K Greene et al.

Journal of thrombosis and haemostasis : JTH, 12(12), 2102-2112 (2014-10-08)

Ectopically expressed B-domainless factor VIII in megakaryocytes is stored in α-granules, is effective in a number of murine hemostatic models, and is protected from circulating inhibitors. However, this platelet (p) FVIII has different temporal-spatial availability from plasma FVIII, with limited efficacy

A signaling pathway consisting of miR-551b, catalase and MUC1 contributes to acquired apoptosis resistance and chemoresistance.

Xiuling Xu et al.

Carcinogenesis, 35(11), 2457-2466 (2014-08-03)

Acquired chemoresistance is a major challenge in cancer therapy. While the oncoprotein Mucin-1 (MUC1) performs multiple roles in the development of diverse human tumors, whether MUC1 is involved in acquired chemoresistance has not been determined. Using an acquired chemoresistance lung

Antioxidant and anti-inflammatory activity of Potentilla reptans L.

Marina T Tomovic et al.

Acta poloniae pharmaceutica, 72(1), 137-145 (2015-04-09)

Potentilla species have been used in traditional medicine in the treatment of different ailment, disease or malady. Potentilla reptans (P. reptans) has been scarcely studied. The aim of this study was to test antioxidant and anti-inflammatory activity of P. reptans

BIRO1, a cell-permeable BH3 peptide, promotes mitochondrial fragmentation and death of retinoblastoma cells.

Nathalie Allaman-Pillet et al.

Molecular cancer research : MCR, 13(1), 86-97 (2014-08-22)

Retinoblastoma is the most common pediatric intraocular neoplasm. While retinoblastoma development requires the inactivation of both alleles of the retinoblastoma tumor suppressor gene (RB1) in the developing retina, additional genomic changes are involved in tumor progression, which progressively lead to

Glycerophosphodiesterase GDE4 as a novel lysophospholipase D: a possible involvement in bioactive N-acylethanolamine biosynthesis.

Kazuhito Tsuboi et al.

Biochimica et biophysica acta, 1851(5), 537-548 (2015-01-18)

Bioactive N-acylethanolamines include anti-inflammatory palmitoylethanolamide, anorexic oleoylethanolamide, and an endocannabinoid arachidonoylethanolamide (anandamide). In animal tissues, these molecules are biosynthesized from N-acylethanolamine phospholipids directly by phospholipase D-type enzyme or through multi-step routes via N-acylethanolamine lysophospholipids. We previously found that mouse brain

Pistachio (Pistacia vera L.) gum: a potent inhibitor of reactive oxygen species.

M Hilal Sehitoglu et al.

Journal of enzyme inhibition and medicinal chemistry, 30(2), 264-269 (2014-06-19)

In the present study, in order to evaluate antioxidant and radical scavenging properties of Pistachio gum (P-Gum), different bioanalytical methods such as DPPH(•) scavenging activity, DMPD(•+) radical scavenging activity, total antioxidant activity determination by ferric thiocyanate, reducing ability Fe(3+)-Fe(2+) transformation

Application of an optosensing chip based on molecularly imprinted polymer coated quantum dots for the highly selective and sensitive determination of sesamol in sesame oils.

Huilin Liu et al.

Journal of agricultural and food chemistry, 63(9), 2545-2549 (2015-02-24)

A novel optosensing chip was constructed by anchoring the fluorescence sensing material layer based on molecularly imprinted polymer (MIP) coated CdSe/ZnS quantum dots (QDs) on a chip for highly selective and sensitive optosensing of sesamol in sesame oil. Many factors

Concentrated green tea supplement: biological activity and molecular mechanisms.

S Cyboran et al.

Life sciences, 126, 1-9 (2015-02-24)

This study was undertaken to determine the biological activity of a green tea supplement with respect to cells and erythrocyte membranes and the molecular mechanism of that activity. The extract's activity was evaluated on the basis of its hemolytic, antioxidant

Antioxidant and anticholinesterase activities of five wild mushroom species with total bioactive contents.

Gulsen Tel et al.

Pharmaceutical biology, 53(6), 824-830 (2015-02-28)

Recently, mushrooms are interesting natural products to be investigated due to exhibiting various bioactivities. This study determines the antioxidant and anticholinesterase activities of various extracts of five wild mushroom species. In addition, the total bioactive contents, namely, ascorbic acid, β-carotene

Silver wire amplifies the signaling mechanism for IL-1beta production more than silver submicroparticles in human monocytic THP-1 cells.

Hye Jin Jung et al.

PloS one, 9(11), e112256-e112256 (2014-11-15)

Silver materials have been widely used in diverse fields. However, their toxicity and their mechanism, especially in different forms, have not been studied sufficiently. Thus, cytotoxicity, apoptosis, and interleukin-1beta (IL-1β) production were investigated using macrophage-like THP-1 cells in the presence

Polyethylenimine-coated SPIONs trigger macrophage activation through TLR-4 signaling and ROS production and modulate podosome dynamics.

Vladimir Mulens-Arias et al.

Biomaterials, 52, 494-506 (2015-03-31)

Polyethylenimine (PEI) is widely used as transfection agent in preclinical studies, both in vitro and in vivo. Due to their unique chemical and physical properties, SPIONs (superparamagnetic iron oxide nanoparticles) have been thoroughly studied as nanocarriers. PEI appears to activate different immune

Role of the rttA gene in morphogenesis, stress response, and virulence in the human pathogenic fungus Penicillium marneffei.

Sumanun Suwunnakorn et al.

Medical mycology, 53(2), 119-131 (2014-12-21)

Penicillium marneffei is a human pathogenic fungus and the only thermally dimorphic species of the genus. At 25°C, P. marneffei grows as a mycelium that produces conidia in chains. However, when incubated at 37°C or following infection of host tissue

Lipophilic antioxidants prevent lipopolysaccharide-induced mitochondrial dysfunction through mitochondrial biogenesis improvement.

Pedro Bullón et al.

Pharmacological research, 91, 1-8 (2014-12-03)

Oxidative stress is implicated in several infectious diseases. In this regard, lipopolysaccharide (LPS), an endotoxic component, induces mitochondrial dysfunction and oxidative stress in several pathological events such as periodontal disease or sepsis. In our experiments, LPS-treated fibroblasts provoked increased oxidative

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