Merck
CN
Search Within

PHR1324

Applied Filters:
Keyword:'PHR1324'
Showing 1-30 of 82 results for "PHR1324" within Papers
Chong Hyun Suh et al.
Radiology, 272(2), 504-513 (2014-04-05)
To determine the utility of intravoxel incoherent motion (IVIM)-derived perfusion and diffusion parameters for differentiation of atypical primary central nervous system lymphoma (PCNSL) from glioblastoma in patients who do not have acquired immunodeficiency syndrome. The institutional review board approved this
Patrick Asbach et al.
Acta radiologica (Stockholm, Sweden : 1987), 55(3), 266-272 (2013-10-01)
Optimal vessel contrast is a prerequisite for vascular imaging. Consecutive stationary imaging of multiple fields of view is contrary to the continuous contrast material passage through the vascular tree. A continuous acquisition of a magnetic resonance (MR) sequence might overcome
Giuseppe Salvaggio et al.
La Radiologia medica, 119(4), 215-221 (2013-12-04)
This study was undertaken to compare response evaluation criteria in solid tumours (RECIST) 1.1 and modified RECIST (mRECIST) in patients with unresectable hepatocellular carcinoma (HCC) on sorafenib, and to describe HCC enhancement changes before and after sorafenib treatment. Seventeen patients
Joo Han Oh et al.
The American journal of sports medicine, 42(11), 2567-2573 (2014-09-07)
The failure of subacromial decompression may be attributed to persistent symptoms of acromioclavicular joint (ACJ) arthritis, while inferior clavicular spurs of the ACJ may be associated with failed healing of repaired rotator cuffs. To evaluate the clinical effectiveness of arthroscopic
Jingqi Zhu et al.
Oncology letters, 9(1), 201-208 (2014-12-02)
Extragastrointestinal stromal tumors (EGISTs) are rare mesenchymal tumors that originate outside the gastrointestinal tract. The aim of the present study was to investigate the computed tomography (CT) and magnetic resonance imaging (MRI) features of EGISTs and analyze the correlations between
Pavla Plačková et al.
Journal of enzyme inhibition and medicinal chemistry, 30(1), 57-62 (2014-04-01)
6-Chloropurines substituted at the position 9 with variously modified bicyclic skeletons represent promising antiviral and anticancer agents. This work aimed to investigate the transport mechanisms of 9-[(1R*,2R*,4S*)-bicyclo[2.2.1]hept-2-yl]-6-chloro-9H-purine (9-norbornyl-6-chloropurine, NCP) and their relationship to the metabolism and biological activity of the
Philipp Kickingereder et al.
Radiology, 272(3), 843-850 (2014-05-13)
To compare multiparametric diagnostic performance with diffusion-weighted, dynamic susceptibility-weighted contrast material-enhanced perfusion-weighted, and susceptibility-weighted magnetic resonance (MR) imaging for differentiating primary central nervous system lymphoma (PCNSL) and atypical glioblastoma. This retrospective study was institutional review board-approved and informed consent was
Stacey Watkins et al.
Nature communications, 5, 4196-4196 (2014-06-20)
Astrocytic endfeet cover the entire cerebral vasculature and serve as exchange sites for ions, metabolites and energy substrates from the blood to the brain. They maintain endothelial tight junctions that form the blood-brain barrier (BBB) and release vasoactive molecules that
Stephen Estes et al.
Developmental neurobiology, 75(5), 435-451 (2014-09-25)
The electrical activity in developing and mature neurons determines the intracellular calcium concentration ([Ca(2+)]i), which in turn is translated into biochemical activities through various signaling cascades. Electrical activity is under control of neuromodulators, which can alter neuronal responses to incoming
Lourens F H J Robbers et al.
Radiology, 272(1), 113-122 (2014-03-13)
To investigate the effects of cell therapy on myocardial perfusion recovery after treatment of acute myocardial infarction (MI) with primary percutaneous coronary intervention (PCI). In this HEBE trial substudy, which was approved by the institutional review board (trial registry number
Kyung-Jo Kim et al.
Inflammatory bowel diseases, 21(1), 101-109 (2014-10-31)
Diffusion-weighted imaging (DWI) is a novel technique to evaluate bowel inflammation in Crohn's disease (CD). It is unknown whether and how DWI adds to the accuracy of conventional magnetic resonance enterography (MRE). Fifty consecutive adults suspected of CD prospectively underwent
María F García Bustos et al.
The Journal of parasitology, 100(6), 840-847 (2014-07-12)
Leishmaniasis, a disease caused by parasites of the Leishmania genus, constitutes a significant health and social problem in many countries and is increasing worldwide. The conventional treatment, meglumine antimoniate (MA), presents numerous disadvantages, including invasiveness, toxicity, and frequent therapeutic failure
Gilles Barone-Rochette et al.
Journal of magnetic resonance imaging : JMRI, 40(6), 1347-1354 (2013-12-03)
To determine the value of cardiac MRI for the monitoring and the prognosis of patients with acute myocarditis. Cardiac MRI plays an increasingly important role in the diagnosis of acute myocarditis. However, it is less established as a prognostic tool
Ho Sung Kim et al.
Radiology, 273(3), 831-843 (2014-06-03)
To compare the added value of dynamic contrast material-enhanced ( CE contrast enhanced ) ( DCE dynamic CE ) magnetic resonance (MR) imaging with that of dynamic susceptibility CE contrast enhanced ( DSC dynamic susceptibility CE ) MR imaging with
Se Jin Ahn et al.
Korean journal of radiology, 15(6), 739-745 (2014-12-04)
To compare the image quality of shoulder CT arthrography performed using 120 kVp and 140 kVp protocols. Fifty-four CT examinations were prospectively included. CT scans were performed on each patient at 120 kVp and 140 kVp; other scanning parameters were
Development and validation of a new HPLC-MS method for meglumine impurity profiling
Martano C, et al.
Journal of Pharmaceutical and Biomedical Analysis, 149(37), 517-524 (2018)
Suk Jae Kim et al.
Annals of neurology, 76(3), 356-369 (2014-07-06)
Dedicated magnetic resonance (MR) imaging (MRI) sequences for evaluation of collaterals can be generated using MR perfusion (MRP) source data. We compared a novel collateral flow imaging technique with digital subtraction angiography (DSA) for determining collateral circulation in acute stroke
Eli Eikefjord et al.
AJR. American journal of roentgenology, 204(3), W273-W281 (2015-02-26)
OBJECTIVE. The purpose of this article is to compare two 3D dynamic contrast-enhanced (DCE) MRI measurement techniques for MR renography, a radial k-space weighted image contrast (KWIC) sequence and a cartesian FLASH sequence, in terms of intrasubject differences in estimates
Riham H El Khouli et al.
Radiology, 272(1), 79-90 (2014-03-14)
To evaluate the effects of breast compression on breast cancer masses, contrast material enhancement of glandular tissue, and quality of magnetic resonance (MR) images in the identification and characterization of breast lesions. This was a HIPAA-compliant, institutional review board-approved retrospective
Lin Zhong et al.
Drug development and industrial pharmacy, 40(12), 1660-1669 (2013-10-09)
The amorphous solid dispersions of telmisartan salts were prepared by cogrinding, in presence of alkalizers and polyvinylpyrrolidone (PVPk30). Five alkalizers in this study were MgO, Na2CO3, K2CO3, NaHCO3 and meglumine. In soft mode using a roll mill, the drug could
Maren Weber et al.
The Journal of biological chemistry, 289(27), 18668-18679 (2014-05-23)
The neuron-specific cation chloride cotransporter KCC2 plays a crucial role in hyperpolarizing synaptic inhibition. Transporter dysfunction is associated with various neurological disorders, raising interest in regulatory mechanisms. Phosphorylation has been identified as a key regulatory process. Here, we retrieved experimentally
L S Wong et al.
European journal of pediatrics, 173(8), 1095-1101 (2014-03-25)
Vesicoureteric reflux has been associated with paediatric urinary tract infection. Fluoroscopic micturating cystourethrography (MCU) has been the gold standard of diagnostic test for decades; however, it has been criticized owing to its lower detection rate and radiation dose to children.
J T Howard et al.
Journal of veterinary pharmacology and therapeutics, 37(6), 531-541 (2014-04-16)
Drug use in livestock has received increased attention due to welfare concerns and food safety. Characterizing heterogeneity in the way swine populations respond to drugs could allow for group-specific dose or drug recommendations. Our objective was to determine whether drug
Panagiotis G Xenoulis et al.
Veterinary parasitology, 203(3-4), 326-330 (2014-05-13)
Canine leishmaniosis (CanL) caused by Leishmania infantum is an important zoonotic disease. One of the most commonly used drugs for the treatment of CanL is meglumine antimonate. Drugs of this class have been associated with pancreatitis and cardiotoxicity in humans
Hubert Cochet et al.
Radiology, 271(1), 239-247 (2014-01-31)
To demonstrate the feasibility of comprehensive assessment of cardiac arrhythmias by combining body surface electrocardiographic (ECG) mapping (BSM) and imaging. This study was approved by the institutional review board, and all patients gave written informed consent. Twenty-seven patients referred for
Toshiyuki Nagai et al.
Chest, 146(4), 1064-1072 (2014-05-24)
Cardiac death is the leading cause of mortality associated with sarcoidosis in Japan. However, the involvement of sarcoidosis infiltration often remains undetected. Recently, late gadolinium enhancement with cardiovascular MRI (LGE-CMR) imaging has been introduced for the detection of myocardial infiltrative
Simultaneous determination of positive and negative pharmaceutical counterions using mixed-mode chromatography coupled with charged aerosol detector
Zhang K, et al.
Journal of Chromatography A, 1217(37), 5776-5784 (2010)
P Omoumi et al.
Osteoarthritis and cartilage, 23(2), 224-231 (2014-12-03)
To evaluate the thickness of cartilage at the posterior aspect of the medial and lateral condyle in Osteoarthritis (OA) knees compared to non-OA knees using computed tomography arthrography (CTA). 535 consecutive knee CTAs (mean patient age = 48.7 ± 16.0;
K Takeishi et al.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 15(1), 155-160 (2014-12-19)
Our aim was to determine whether variant bile duct (BD) anatomy is associated with portal vein (PV) and/or hepatic artery (HA) anatomy. We examined the associations between BD anatomy and PV and/or HA anatomy in 407 living donor transplantation donors.
Nicola Galea et al.
La Radiologia medica, 119(5), 309-317 (2013-12-18)
The aim of this work was to compare the prevalence of right ventricle involvement in a population of patients with myocardial infarction as detected by cardiac magnetic resonance (CMR), clinical presentation, electrocardiographic (ECG) and echocardiographic criteria. A total of 97
Page 1 of 3