PHR1384

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Showing 1-16 of 16 results for "PHR1384" within Papers

Patient education and self-care for the management of jaw pain upon awakening: a randomized controlled clinical trial comparing the effectiveness of adding pharmacologic treatment with cyclobenzaprine or tizanidine.

Francisco Guedes Pereira Alencar et al.

Journal of oral & facial pain and headache, 28(2), 119-127 (2014-05-14)

To compare the effectiveness of adding cyclobenzaprine, tizanidine, or placebo to patient education and a self-care management program for patients with myofascial pain and specifically presenting with jaw pain upon awakening. Forty-five patients with a diagnosis of myofascial pain based

A phase III randomized, placebo-controlled study of topical amitriptyline and ketamine for chemotherapy-induced peripheral neuropathy (CIPN): a University of Rochester CCOP study of 462 cancer survivors.

Jennifer S Gewandter et al.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 22(7), 1807-1814 (2014-02-18)

Chemotherapy-induced peripheral neuropathy (CIPN) occurs in as high as 70% of patients receiving certain types of chemotherapy agents. The FDA has yet to approve a therapy for CIPN. The aim of this multicenter, phase III, randomized, double-blind, placebo-controlled trial was

Spectrophotometric and chromatographic simultaneous estimation of amitriptyline hydrochloride and chlordiazepoxide in tablet dosage forms

Patel S, et al.

Indian Journal of Pharmaceutical Sciences, 71(4), 472-472 (2009)

Salt effects in electromembrane extraction.

Knut Fredrik Seip et al.

Journal of chromatography. A, 1347, 1-7 (2014-05-06)

Electromembrane extraction (EME) was performed on samples containing substantial amounts of NaCl to investigate how the presence of salts affected the recovery, repeatability, and membrane current in the extraction system. A group of 17 non-polar basic drugs with various physical

Ultrasound-assisted combined with nano-sized molecularly imprinted polymer for selective extraction and pre-concentration of amitriptyline in human plasma with gas chromatography-flame detection.

Salah Khanahmadzadeh et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 972, 6-13 (2014-10-13)

A new process was developed for the selective extraction and pre-concentration of amitriptyline (AT) from human plasma using nano-sized molecularly imprinted polymer (MIP) with ultrasound-assisted extraction (UAE). The nano-sized AT imprinted polymer particles were synthesized using suspension polymerization in silicon

Chronic administration of amitriptyline differentially alters neuropathic pain-related behaviour in the presence and absence of a depressive-like phenotype.

Nikita N Burke et al.

Behavioural brain research, 278, 193-201 (2014-10-11)

Chronic pain and depression share a complex, reciprocal relationship. Furthermore, in addition to treating depression, antidepressants such as amitriptyline are a first-line treatment for chronic pain conditions, indicating possible common neural substrates underlying both depression and pain. However, there is

Chronic idiopathic nausea of childhood.

Katja Kovacic et al.

The Journal of pediatrics, 164(5), 1104-1109 (2014-03-13)

To compare children with primary, chronic idiopathic nausea to those with secondary nausea associated with functional abdominal pain. Retrospective chart review of 45 children with a primary complaint of chronic nausea several times per week. Comparisons were made to prospectively

An investigation of the stability of emerging new psychoactive substances.

Yan Ni Annie Soh et al.

Drug testing and analysis, 6(7-8), 696-704 (2014-02-28)

The evolving nature of new psychoactive substances (NPS) - often referred to as 'legal highs', 'designer drugs' or 'bath salts' - presents an evolving challenge for toxicologists. Apart from the detection and identification of these compounds, further analytical challenges may

Simultaneous spectrophotometric determination of amitriptyline hydrochloride and chlordiazepoxide in pharmaceutical tablets by multivariate calibration method

Sarrafi MHA, et al.

Journal of Chemistry, 6(S1), S111-S116 (2009)

Analgesic effects of antidepressants alone and after their local co-administration with morphine in a rat model of neuropathic pain.

Grzegorz Jagla et al.

Pharmacological reports : PR, 66(3), 459-465 (2014-06-07)

The therapy of neuropathic pain may include the use of co-analgesics, such as antidepressants, however, their desired analgesic effect is associated with significant side effects. An alternative approach to this is their local administration which has been proposed, but there

Application of electro-enhanced solid phase microextraction combined with gas chromatography-mass spectrometry for the determination of tricyclic antidepressants in environmental water samples.

Ruyi Xu et al.

Journal of chromatography. A, 1350, 15-22 (2014-05-28)

A fast and efficient method for the determination of tricyclic antidepressants using electro-enhanced solid phase microextraction (SPME) coupled to gas chromatography-mass spectrometry (GC-MS) has been developed. One advantage of this approach is that the mass transfer of target analytes from

Optimization and pharmacological characterization of a refined cisplatin-induced rat model of peripheral neuropathic pain.

Felicity Yaqin Han et al.

Behavioural pharmacology, 25(8), 732-740 (2014-10-18)

Chemotherapy-induced peripheral neuropathy (CIPN) is the major dose-limiting side-effect of many front-line anticancer drugs. This study was designed to establish and pharmacologically characterize a refined rat model of cisplatin-induced CIPN. Adult male Sprague-Dawley rats received four (n=18) or five (n=18)

Growth inhibition and coordinated physiological regulation of zebrafish (Danio rerio) embryos upon sublethal exposure to antidepressant amitriptyline.

Ming Yang et al.

Aquatic toxicology (Amsterdam, Netherlands), 151, 68-76 (2014-01-23)

Amitriptyline is a tricyclic antidepressant used for decades. It is present at low detectable concentrations in the aquatic environment, but relative few studies have focused on its ecotoxicological effects on non-target aquatic animals. The present study conducted an acute toxicity

Modeling nociception in zebrafish: a way forward for unbiased analgesic discovery.

Andrew Curtright et al.

PloS one, 10(1), e0116766-e0116766 (2015-01-15)

Acute and chronic pain conditions are often debilitating, inflicting severe physiological, emotional and economic costs and affect a large percentage of the global population. However, the development of therapeutic analgesic agents based primarily on targeted drug development has been largely

Influence of combined therapy with rosuvastatin and amitriptyline on the oxidation-reduction status in rats.

Mariola Herbet et al.

Acta poloniae pharmaceutica, 70(5), 913-917 (2013-10-24)

The aim of the present study was to assess the impact of combined therapy with rosuvastatin (10 mg/kg) and amitriptyline (10 mg/kg) on oxidation-reduction status in the blood of rats. After 2-week application of drugs alone or their combination, the

Treatment of epidermolysis bullosa pruriginosa using systemic and topical agents.

Aaron R Mangold et al.

Journal of the American Academy of Dermatology, 70(6), e136-e137 (2014-05-17)

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