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Showing 1-30 of 40 results for "PHR1469" within Papers
Jie Meng et al.
Molecular cancer therapeutics, 13(12), 3107-3122 (2014-10-04)
This study was conducted to examine the effects of doxycycline on the survival time and proliferation of hepatocellular carcinoma (HCC) in vivo and on the biologic functions of HCC in vitro. This study was also designed to evaluate the effects
Filomena Aste Silveira et al.
Experimental and molecular pathology, 98(2), 308-311 (2015-01-13)
DNA methylation is the most important epigenetic change involved in the control of gene expression in human cells. Methylation of the p16(INK4a) gene occurs early in the development of cervical cancer. Low-grade squamous intraepithelial lesions (LSILs) are prevalent, and their
Shaik Mohammad Naushad et al.
Molecular and cellular biochemistry, 392(1-2), 273-280 (2014-03-29)
Obesity, genetic polymorphisms of xenobiotic metabolic pathway, hypermethylation of tumor suppressor genes, and hypomethylation of proapoptotic genes are known to be independent risk factors for breast cancer. The objective of this study is to evaluate the combined effect of these
Carlo Foresta et al.
Human reproduction (Oxford, England), 29(6), 1134-1145 (2014-04-29)
What are the dynamics of zinc (Zn) trafficking in sperm, at the testicular, epididymal and ejaculate levels? Zn transporters are peculiarly expressed in the cells of the germ line and Zn uptake is maximal at the post-epididymal phase, where Zn
Ayman M Atta et al.
Molecules (Basel, Switzerland), 19(5), 6246-6262 (2014-05-21)
A facile method was developed to synthesize in high yield dispersed silver nanoparticles (AgNPs) with small particle sizes of less than 10 nm. Silver nitrate was reduced to silver nanoparticles by p-chloroaniline in the presence of polyoxyethylene maleate 4-nonyl-2-propylene-phenol (NMA)
Jiyeon Yang et al.
Environmental geochemistry and health, 37(2), 321-332 (2014-09-27)
The objective of this study is to find the Cd levels in agricultural crops compared to soil, to evaluate the relationship between daily intake dose through the multimedia/multi-pathway of human exposure and biomarker levels of the residents in mine vicinity
Ren-Qi Wang et al.
Analytica chimica acta, 853, 608-616 (2014-12-04)
A hydrophilic interaction liquid chromatography (HILIC) method was developed to measure the composition of humic substances from river, reservoir, and treated wastewater based on their physicochemical properties. The current method fractionates the humic substances into four well-defined groups based on
Chi-Feng Hung et al.
International journal of pharmaceutics, 471(1-2), 135-145 (2014-05-27)
Intrinsic aging and photoaging modify skin structure and components, which subsequently change percutaneous absorption of topically applied permeants. The purpose of this study was to systematically evaluate drug/sunscreen permeation via young and senescent skin irradiated by ultraviolet (UV) light. Both
Fanny Ramel et al.
PloS one, 10(4), e0123455-e0123455 (2015-04-04)
Although obligate anaerobe, the sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough (DvH) exhibits high aerotolerance that involves several enzymatic systems, including two membrane-bound oxygen reductases, a bd-quinol oxidase and a cc(b/o)o3 cytochrome oxidase. Effect of constant low oxygen concentration on growth and
M Yokono et al.
Nature communications, 6, 6675-6675 (2015-03-27)
Throughout the history of oxygen evolution, two types of photosystem reaction centres (PSI and PSII) have worked in a coordinated manner. The oxygen evolving centre is an integral part of PSII, and extracts an electron from water. PSI accepts the
Richard T Penson et al.
The Lancet. Oncology, 16(3), 301-311 (2015-02-02)
GOG 240 was a practice-changing randomised phase 3 trial that concluded that chemotherapy plus bevacizumab for advanced cervical cancer significantly improves overall and progression-free survival, and the proportion of patients achieving an overall objective response, compared with chemotherapy alone. In
Yan-Fang Tao et al.
Journal of experimental & clinical cancer research : CR, 34, 4-4 (2015-01-23)
Pediatric acute myeloid leukemia (AML) comprises up to 20% of all childhood leukemia. Recent research shows that aberrant DNA methylation patterning may play a role in leukemogenesis. The epigenetic silencing of the EBF3 locus is very frequent in glioblastoma. However
Ludovic Peyre et al.
Toxicology in vitro : an international journal published in association with BIBRA, 28(8), 1507-1520 (2014-07-06)
Pesticides as well as many other environmental pollutants are considered as risk factors for the initiation and the progression of cancer. In order to evaluate the in vitro effects of chemicals present in the diet, we began by combining viability
E Roemer et al.
Regulatory toxicology and pharmacology : RTP, 70 Suppl 1, S2-14 (2014-12-17)
This publication introduces a series of six other publications describing the toxicological assessment of kretek cigarettes, i.e., cigarettes characterized primarily by the use of a significant amount of cloves as an ingredient added to the tobacco. This paper presents background
Xiuxing Wang et al.
Biochemical and biophysical research communications, 457(4), 514-519 (2015-01-15)
MILI, a member of the PIWI/AGO gene family, has been well documented to maintain genome integrity by transposon silencing in animal germ cells. It has been reported to be selectively expressed in precancerous stem cells (pCSCs), tumor cell lines and
Felix W Friedrich et al.
Basic research in cardiology, 109(6), 451-451 (2014-11-02)
Based on evidence that FHL2 (four and a half LIM domains protein 2) negatively regulates cardiac hypertrophy we tested whether FHL2 altered expression or variants could be associated with hypertrophic cardiomyopathy (HCM). HCM is a myocardial disease characterized by left
G Karanikolopoulos et al.
Food chemistry, 177, 197-203 (2015-02-11)
Reliable methods for quantification of synthetic water-soluble colors in complex food matrices are currently not available. The present work describes the development and validation of an improved protocol for the analysis of synthetic food colorants in complex food matrices presenting
Y-A Bae et al.
Parasitology, 142(6), 807-815 (2015-01-27)
Trematode tyrosinases (TYRs) play a major role in the tanning process during eggshell formation. We investigated the molecular and biochemical features of Paragonimus westermani TYR (PwTYR). The PwTYR cDNA was composed of 1568-bp encompassing a 1422-bp-long open reading frame (474-amino
Automated flow-injection spectrophotometric determination of catecholamines (epinephrine and isoproterenol) in pharmaceutical formulations based on ferrous complex formation.
Solich P, et al.
Journal of Pharmaceutical and Biomedical Analysis, 22(5), 781-789 (2000)
John T Wilson et al.
The AAPS journal, 17(2), 358-369 (2014-12-17)
Protein-based vaccines offer a number of important advantages over organism-based vaccines but generally elicit poor CD8(+) T cell responses. We have previously demonstrated that pH-responsive, endosomolytic polymers can enhance protein antigen delivery to major histocompatibility complex class I (MHC-I) antigen
Changming Chen et al.
Plant physiology, 166(1), 370-383 (2014-07-23)
A seed's ability to properly germinate largely depends on its oxidative poise. The level of reactive oxygen species (ROS) in Arabidopsis (Arabidopsis thaliana) is controlled by a large gene network, which includes the gene coding for the hydrogen peroxide-scavenging enzyme
Yara Furtado et al.
Experimental and molecular pathology, 98(1), 119-123 (2015-01-13)
To analyze the presence of HPV-DNA and TIMP-2 gene methylation in cervical precursor and invasive lesions, as well as to study the associations among the latter, the presence of HPV-DNA, and the clinical evolution of such lesions. Cross-sectional study that
Jun-Jun Liu et al.
BMC plant biology, 14, 380-380 (2014-12-31)
Western white pine (WWP, Pinus monticola Douglas ex D. Don) is of high interest in forest breeding and conservation because of its high susceptibility to the invasive disease white pine blister rust (WPBR, caused by the fungus Cronartium ribicola J.
I Ojeda et al.
Analytical and bioanalytical chemistry, 406(25), 6363-6371 (2014-08-02)
A novel magnetoimmunosensor design for interleukin-6 (IL-6) which involved the covalent immobilization of anti-IL-6 antibodies onto carboxyl-functionalized magnetic microparticles and a sandwich-type immunoassay with signal amplification using poly-HRP-streptavidin conjugates is reported. All the variables concerning the preparation and the electroanalytical
Ping Yang et al.
Investigative ophthalmology & visual science, 55(5), 3012-3021 (2014-03-29)
Retinal pigment epithelial (RPE) cell death is an important feature of the advanced forms of AMD. Complement alternative pathway (AP) activation is associated with RPE cell death in AMD. In this study, we developed a new model to initiate AP
Nicholas M Contento et al.
Biomicrofluidics, 8(4), 044120-044120 (2014-11-08)
Electrochemistry is a promising tool for microfluidic systems because it is relatively inexpensive, structures are simple to fabricate, and it is straight-forward to interface electronically. While most widely used in microfluidics for chemical detection or as the transduction mechanism for
U Eletxigerra et al.
Analytica chimica acta, 838, 37-44 (2014-07-30)
An amperometric immunoassay for the determination of tumor necrosis factor alpha (TNFα) protein biomarker in human serum based on the use of magnetic microbeads (MBs) and disposable screen-printed carbon electrodes (SPCEs) has been developed. The specifically modified microbeads were magnetically
Kosuke Sato et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(13), 5034-5040 (2015-02-14)
In biomineralization, acidic macromolecules play important roles for the growth control of crystals through a specific interaction. Inspired by this interaction, we report on an application of the hierarchical structures in CaCO3 biominerals to a stationary phase of chromatography. The
Michał Szumski et al.
Journal of chromatography. A, 1373, 114-123 (2014-12-04)
A novel, cholesterol-based polymeric monolithic stationary phase for capillary liquid chromatography, was prepared by thermally initiated in-situ polymerization. Cholesteryl methacrylate (CholMA) was used as a functional monomer and trimethylolpropane trimethacrylate (TRIM) was a cross-linker, while azobisisobutyronitrile (AIBN) was an initiator.
Ling Feng et al.
Environmental science and pollution research international, 21(14), 8406-8416 (2014-04-24)
The electrochemical degradation of the nonsteroidal anti-inflammatory drug ketoprofen in tap water has been studied using electro-Fenton (EF) and anodic oxidation (AO) processes with platinium (Pt) and boron-doped diamond (BDD) anodes and carbon felt cathode. Fast degradation of the parent
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