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Showing 1-30 of 43 results for "RAB0537" within Papers
Donghao Li et al.
Pharmacognosy magazine, 13(52), 677-682 (2017-12-05)
To investigate the effect of berberine (BBR) on intestinal barrier function in nonalcoholic fat liver disease (NAFLD) in rats. Rats were divided into three groups: normal diet group (control group [CON group]), high-fat diet feeding group (HFD group), and HFD
H A G Ducray et al.
Journal of applied microbiology, 128(4), 1163-1178 (2019-12-10)
To characterize efficacy of the Bacillus subtilis BSB3 (BSB3) strain in the prevention of excessive exercise-induced side effects and in maintaining stability of the gut microbiota. Rats were pretreated by oral gavage with B. subtilis BSB3 (BSB3) or with phosphate-buffered
Can Kong et al.
Annals of translational medicine, 7(16), 388-388 (2019-09-27)
The aim of this prospective study was to screen and combine effective biomarkers to improve their diagnostic performance in detecting intestinal barrier dysfunction in patients after major abdominal surgery. Patients undergoing major abdominal surgery were enrolled after signing informed consent
Daniela Paganini et al.
Gut, 66(11), 1956-1967 (2017-08-05)
Iron-containing micronutrient powders (MNPs) reduce anaemia in African infants, but the current high iron dose (12.5 mg/day) may decrease gut In a 4-month, controlled, double-blind trial, we randomised Kenyan infants aged 6.5-9.5 months (n=155) to receive daily (1) a MNP without
Christopher Storm-Larsen et al.
AIDS (London, England), 33(4), 645-653 (2018-12-12)
Translocation of microbial products such as lipopolysaccharides (LPS) from the gut may contribute to chronic inflammation in HIV-infected individuals. Recent studies indicate that differences in degree of acylation of gut-bacterial-derived LPS may explain variable immune effects, with hexa-acylated rather than
Derrick R Samuelson et al.
PLoS pathogens, 13(6), e1006426-e1006426 (2017-06-13)
Chronic alcohol consumption perturbs the normal intestinal microbial communities (dysbiosis). To investigate the relationship between alcohol-mediated dysbiosis and pulmonary host defense we developed a fecal adoptive transfer model, which allows us to investigate the impact of alcohol-induced gut dysbiosis on
Elisa Karhu et al.
European journal of applied physiology, 117(12), 2519-2526 (2017-10-17)
Athletes frequently experience gastrointestinal (GI) symptoms during training and competition. Although the prevalence of exercise-induced GI symptoms is high, the mechanisms leading to GI distress during exercise are not fully understood. The aim of this study was to identify running-induced
A novel approach to the nutrigenetics and nutrigenomics of obesity and weight management.
Joffe Y T and Christine A H
Current Oncology Reports, 18(7), 43-43 (2016)
Jean-Paul Decuypere et al.
International journal of molecular sciences, 21(19) (2020-10-03)
Renal ischemia-reperfusion (IR) injury leading to cell death is a major cause of acute kidney injury, contributing to morbidity and mortality. Autophagy counteracts cell death by removing damaged macromolecules and organelles, making it an interesting anchor point for treatment strategies.
Natalia Drabińska et al.
Nutrients, 12(6) (2020-06-14)
Abnormalities in the intestinal barrier are a possible cause of celiac disease (CD) development. In animal studies, the positive effect of prebiotics on the improvement of gut barrier parameters has been observed, but the results of human studies to date
Shan Wu et al.
Life sciences, 253, 117539-117539 (2020-03-14)
Lipopolysaccharide (LPS)-induced intestinal injury is a common clinical feature of sepsis. Aggravated inflammation and higher sensitivity to infection are associated with high-fat diet (HFD) in patients with type 2 diabetes and/or obesity. However, the mechanism by which HFD exacerbates LPS-induced
Michael Reid et al.
AIDS (London, England), 31(3), 385-393 (2017-01-13)
HIV/hepatitis C virus (HCV) coinfection is associated with insulin resistance, but the mechanism is unclear. We hypothesized that intestinal epithelial damage and the consequent monocyte/macrophage activation and inflammation explain this perturbation. Cross-sectional study of 519 adults (220 HIV+/HCV-; 64 HIV-/HCV+;
Ozge Surmeli Onay et al.
European journal of pediatrics, 179(4), 561-570 (2019-12-20)
We aimed to investigate the role of hypoxia-ischemia in the pathophysiology of early NEC/NEC like disease (ENEC) and classic NEC/NEC like disease (CNEC) in preterm infants. In this pilot study, preterm infants who developed the clinical symptoms and signs of
Rosalie H Bartels et al.
Scientific reports, 9(1), 2304-2304 (2019-02-21)
Intestinal pathology in children with complicated severe acute malnutrition (SAM) persists despite standard management. Given the similarity with intestinal pathology in non-IgE mediated gastrointestinal food allergy and Crohn's disease, we tested whether therapeutic feeds effective in treating these conditions may
Salma A Khattab et al.
Journal of diabetes, 9(9), 821-826 (2016-10-26)
Intestinal fatty acid-binding protein 2 (FABP2) is expressed in enterocytes and binds saturated and unsaturated long-chain fatty acids. The FABP2 Ala54Thr polymorphism has been reported to effect lipid metabolism. The aim of the present study was to assess the relationship
Lisa Wrba et al.
Shock (Augusta, Ga.), 52(4), e45-e51 (2018-10-06)
Dysfunction of the gut-blood barrier plays an important role in many diseases, such as inflammatory bowel disease, hemorrhagic shock (HS), or burn injury. However, little is known about gut barrier dysfunction after hemodynamically instable polytrauma (PT). Therefore, we aimed to
Luca Maccioni et al.
Gut microbes, 12(1), 1782157-1782157 (2020-06-27)
Animal data suggest a role of the gut-liver axis in progression of alcoholic liver disease (ALD), but human data are scarce especially for early disease stages. We included patients with alcohol use disorder (AUD) who follow a rehabilitation program and
Meike Baur et al.
PloS one, 15(6), e0235220-e0235220 (2020-06-26)
Approximately 30,000 patients with blunt cardiac trauma are recorded each year in the United States. Blunt cardiac injuries after trauma are associated with a longer hospital stay and a poor overall outcome. Organ damage after trauma is linked to increased
Giuseppe Ancona et al.
Frontiers in immunology, 12, 639291-639291 (2021-03-16)
Background: We explored the long-term effects of cART on markers of gut damage, microbial translocation, and paired gut/blood microbiota composition, with a focus on the role exerted by different drug classes. Methods: We enrolled 41 cART naïve HIV-infected subjects, undergoing
Garrett W Hill et al.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 45(4), 376-386 (2019-09-11)
This study examined the impact of treadmill running in normobaric hypoxia on gastrointestinal barrier permeability and the systemic inflammatory response. Ten recreationally active participants completed two 1-h bouts of matched-workload treadmill exercise (65% normoxic maximal oxygen consumption) in counterbalanced order.
Sahera Dirajlal-Fargo et al.
Open forum infectious diseases, 5(11), ofy291-ofy291 (2018-12-06)
This study was conducted to explore the associations between serum albumin and markers of inflammation and cardiovascular disease in treated human immunodeficiency virus (HIV)-infected adults. We conducted a nested study within in the SATURN-HIV trial in which 147 HIV+ adults
Intestinal FABP2 A54T polymorphism: association with insulin resistance and obesity in women.
Albala C, et al.
Obesity Research, 12(2), 340-345 (2004)
Diana E Matei et al.
Med (New York, N.Y.), 2(7), 864-883 (2021-07-24)
Evidence suggests an important role for gut-microbiota dysbiosis in the development of rheumatoid arthritis (RA). The link between changes in gut bacteria and the development of joint inflammation is missing. Here, we address whether there are changes to the gut
Marina Saresella et al.
Frontiers in immunology, 11, 1390-1390 (2020-08-01)
Background: Butyric acid (BA) is a short-chain fatty acid (SCFA) with anti-inflammatory properties, which promotes intestinal barrier function. Medium-chain fatty acids (MCFA), including caproic acid (CA), promote TH1 and TH17 differentiation, thus supporting inflammation. Aim: Since most SCFAs are absorbed
Albert Shieh et al.
JCI insight, 5(2) (2019-12-13)
BACKGROUNDInflammation is implicated in many aging-related disorders. In animal models, menopause leads to increased gut permeability and inflammation. Our primary objective was to determine if gut permeability increases during the menopause transition (MT) in women. Our exploratory objectives were to
Doungnapa Kantamala et al.
Cytokine, 136, 155257-155257 (2020-08-30)
Individuals residing in areas with high prevalence of foodborne infection could have a higher risk of gut microbial translocation which may affect monocyte activation, gut immune recovery and intestinal epithelial cell damage. We aimed to measure alterations in microbial translocation
Nhan Hyung et al.
Journal of pediatric surgery, 52(7), 1152-1155 (2016-11-27)
To determine the incidence of intestinal mucosal injury before and after transfusions in premature infants. Urine was collected throughout the hospital stay of 62 premature infants and specimens obtained within 24h before and after transfusion were assayed for intestinal fatty
Mandy C Szymanski et al.
Journal of applied physiology (Bethesda, Md. : 1985), 124(2), 330-340 (2017-09-25)
Szymanski MC, Gillum TL, Gould LM, Morin DS, Kuennen MR. Short-term dietary curcumin supplementation reduces gastrointestinal barrier damage and physiological strain responses during exertional heat stress. J Appl Physiol 124: 330-340, 2018. First published September 21, 2017; doi: 10.1152/japplphysiol.00515.2017 .-This
Thr-encoding allele homozygosity at codon 54 of FABP 2 gene may be associated with impaired delta 6 desatruase activity and reduced plasma arachidonic acid in obese children.
Okada T, et al.
Journal of Atherosclerosis and Thrombosis, 13(4), 192-196 (2006)
Hanna Fjeldheim Dale et al.
Nutrients, 11(7) (2019-07-20)
Peptides from fish may beneficially affect several metabolic outcomes, including gut health and inflammation. The effect of fish peptides in subjects with irritable bowel syndrome (IBS) has not previously been investigated, hence this study aimed to evaluate the effect of
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