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Showing 1-15 of 15 results for "S0192" within Papers
Taira Nakayama et al.
PloS one, 14(1), e0210198-e0210198 (2019-01-27)
Various cell-based therapeutic strategies have been investigated for vascular and tissue regeneration after ischemic stroke. We have developed a novel cell population, called regeneration-associated cells (RACs), by quality- and quantity-controlled culture of unfractionated mononuclear cells. RACs were trans-arterially injected into
Shi-Jiang Lu et al.
Nature methods, 4(6), 501-509 (2007-05-09)
Recent evidence suggests the existence of progenitor cells in adult tissues that are capable of differentiating into vascular structures as well as into all hematopoietic cell lineages. Here we describe an efficient and reproducible method for generating large numbers of
Ka-Won Kang et al.
BMC cancer, 20(1), 619-619 (2020-07-04)
We assessed the mechanism of hematopoietic stem cell (HSC) mobilization using etoposide with granulocyte-colony stimulating factor (G-CSF), and determined how this mechanism differs from that induced by cyclophosphamide with G-CSF or G-CSF alone. We compared the clinical features of 173
Annika Wulf-Goldenberg et al.
European journal of cell biology, 87(2), 69-80 (2007-10-13)
Stem cell homing, engraftment and organ regeneration are controlled by cytokines, chemokines and cell-cell interactions. In this paper, cytokine effects on homing- and engraftment-related characteristics of CD34(+) cord blood cells were examined. Untreated CD34(+) cells were mainly in the G(0)/G(1)
Malgorzata Stec et al.
Journal of leukocyte biology, 82(3), 594-602 (2007-06-28)
To determine whether monocytes can be generated from CD34+ hematopoietic progenitors in large numbers, cord blood CD34+ cells were first expanded for 3-10 days in X-VIVO 10 medium supplemented with FCS, stem cell factor (SCF), thrombopoietin (TPO), and Flt-3 Ligand
Hiroyuki Matsubara et al.
Biochemical and biophysical research communications, 515(1), 1-8 (2019-04-06)
Natural killer (NK) cells are innate lymphocytes and show cytotoxicity against tumor cells without prior antigen specific stimulation. Because of their innate properties, NK cells are being considered for immunotherapies against various malignancies or leukemia. Human pluripotent stem cells (hPSCs)
Xinsheng Chen et al.
Stem cell research, 47, 101919-101919 (2020-07-28)
Pendred syndrome (PDS) is hereditary and is characterized by thyroid enlargement, cochlea abnormalities, and hearing impairment. In this study, we established an induced pluripotent stem cell line from a PDS patient with familial thyroid disorder, caused by compound heterozygous mutations
Konstantin Levay et al.
The Journal of clinical investigation, 117(9), 2672-2683 (2007-08-25)
We show here that the process of megakaryocytic differentiation requires the presence of the recently discovered protein tescalcin. Tescalcin is dramatically upregulated during the differentiation and maturation of primary megakaryocytes or upon PMA-induced differentiation of K562 cells. This upregulation requires
Tomohiro Makino et al.
Biochemical pharmacology, 171, 113717-113717 (2019-11-22)
Heritable disorders associated with hemoglobin production are the most common monogenic disorders. These are mainly represented by disorders such as β-thalassemia and sickle cell disease. Induction of fetal hemoglobin (HbF) has been known to ameliorate the clinical severity of these
Ryohichi Sugimura et al.
Biomedical microdevices, 22(2), 34-34 (2020-05-08)
A fundamental limitation in the derivation of hematopoietic stem and progenitor cells is the imprecise understanding of human developmental hematopoiesis. Herein we established a multilayer microfluidic Aorta-Gonad-Mesonephros (AGM)-on-a-chip to emulate developmental hematopoiesis from pluripotent stem cells. The device consists of
Ian McNiece
Seminars in cell & developmental biology, 18(6), 839-845 (2007-11-21)
Advances in stem cell biology and cellular therapy have led to promising treatments in a range of incurable diseases. However, it is unclear whether primitive stem cells can be delivered to damage tissue for regeneration of functional mature cells or
Charles K F Chan et al.
Cell, 175(1), 43-56 (2018-09-23)
Stem cell regulation and hierarchical organization of human skeletal progenitors remain largely unexplored. Here, we report the isolation of a self-renewing and multipotent human skeletal stem cell (hSSC) that generates progenitors of bone, cartilage, and stroma, but not fat. Self-renewing and
Meng Ling Choong et al.
Experimental hematology, 35(4), 551-564 (2007-03-24)
MicroRNA (miRNA) expression profiling was performed on ex vivo differentiating erythroid cultures derived from human umbilical cord blood (UCB) CD34 cells and K562 cells to identify miRNAs involved in erythropoiesis. Both cell types were subjected to growth factor cocktails stimulating
Comparison of Serum-Free Media in RBC Differentiation from Human Hematopoietic Stem Cells
Kim, Ji Yeon. et al
Korean Journal of Blood Transfusion, 26, 18-25 (2015)
Pranav S Renavikar et al.
Frontiers in immunology, 11, 568630-568630 (2020-11-17)
Autoimmune diseases are characterized by regulatory deficit in both the CD4+ and CD8+ T-cell compartments. We have shown that CD8+ T-cells associated with acute relapse of multiple sclerosis are significantly deficient in their immune suppressive ability. We hypothesized that distinct
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