Merck
CN
Search Within

S1876

Applied Filters:
Keyword:'S1876'
Showing 1-30 of 379 results for "S1876" within Papers
Valerio Leoni et al.
Clinical chemistry and laboratory medicine, 42(2), 186-191 (2004-04-06)
24S-Hydroxycholesterol (24OHC) and 27-hydroxycholesterol (27OHC) are two structurally similar oxysterols of different origins--the former almost exclusively formed in the brain and the latter formed to a lesser extent in the brain than in most other organs. HYPOTHESIS TO BE TESTED:
Wu Hao et al.
The Journal of biological chemistry, 290(28), 17106-17115 (2015-05-23)
Diabetes mellitus (DM) is frequently accompanied by complications, such as peripheral nerve neuropathy. Schwann cells play a pivotal role in regulating peripheral nerve function and conduction velocity; however, changes in Schwann cell differentiation status in DM are not fully understood.
Claudia Rasche et al.
Journal of chromatography. A, 1403, 21-31 (2015-06-06)
Some steps of the QuEChERS method for the analysis of pesticides with GC-MS/MS in cereals and dried fruits were improved or simplified. For the latter, a mixing vessel with stator-rotor-system proved to be advantageous. The extraction procedure of dried fruits
Stephanie L Maiden et al.
PloS one, 11(2), e0148574-e0148574 (2016-02-06)
Tight regulation of cadherin-mediated intercellular adhesions is critical to both tissue morphogenesis during development and tissue homeostasis in adults. Cell surface expression of the cadherin-catenin complex is often directly correlated with the level of adhesion, however, examples exist where cadherin
Livan Delgado-Roche et al.
Journal of cardiovascular pharmacology, 61(2), 160-165 (2012-12-12)
Atherosclerosis is a major cause of death in the Western World. It is known that Lipofundin 20% induces atherosclerotic lesions, whereas ozone at low doses has been satisfactorily used in the prevention of oxidative stress-associated pathologies, such as coronary artery
M J Peterson et al.
Metabolism: clinical and experimental, 35(4 Suppl 1), 93-95 (1986-04-01)
Increased flux of glucose through the polyol pathway with resultant resultant accumulation of tissue sorbitol is implicated in the pathogenesis of the chronic complications of diabetes. Sorbinil is a potent inhibitor of aldose reductase (the first enzyme in the polyol
Ziv Harel et al.
The American journal of medicine, 126(3), 264-264 (2013-01-17)
Sodium polystyrene sulfonate (Kayexalate; Sanofi-Aventis, Paris, France) is a cation-exchange resin routinely used in the management of hyperkalemia. However, its use has been associated with colonic necrosis and other fatal gastrointestinal adverse events. Although the addition of sorbitol to sodium
Camille Desgrouas et al.
Malaria journal, 13, 327-327 (2014-08-26)
New classes of anti-malarial drugs are needed to control the alarming Plasmodium falciparum resistance toward current anti-malarial therapy. The ethnopharmacological approach allows the discovery of original chemical structures from the vegetable biodiversity. Previous studies led to the selection of a
Joshua Russell et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(22), 8269-8274 (2014-05-21)
All terrestrial animals must find a proper level of moisture to ensure their health and survival. The cellular-molecular basis for sensing humidity is unknown in most animals, however. We used the model nematode Caenorhabditis elegans to uncover a mechanism for
M A Lovell et al.
Archives of neurology, 58(3), 392-396 (2001-03-20)
Markers of oxidative stress are increased in cerebrospinal fluid (CSF) of patients with Alzheimer disease (AD), although none of those reported are appropriate diagnostic markers because of the overlap between patients with AD and control subjects. To determine the ratio
Haixia Lu et al.
Journal of food science, 80(6), M1325-M1329 (2015-05-15)
Contaminated leafy green vegetables have been linked to several outbreaks of human gastrointestinal infections. Antimicrobial interventions that are adoptable by the fresh produce industry for control of pathogen contamination are in great demand. This study was undertaken to evaluate the
I Thorild et al.
European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 13(6), 305-307 (2012-12-14)
To evaluate the long-term outcome of a mother-child project in which mothers (n=173) with high counts of salivary mutans streptococci were randomly assigned to daily chewing gums containing xylitol (A), chlorhexidine/ xylitol/sorbitol (B), or sodium fluoride/xylitol/sorbitol (C) for one year
Anne Viefhues et al.
Eukaryotic cell, 14(7), 636-651 (2015-05-03)
Important for the lifestyle and survival of every organism is the ability to respond to changing environmental conditions. The necrotrophic plant pathogen Botrytis cinerea triggers an oxidative burst in the course of plant infection and therefore needs efficient signal transduction
Yumin Zhang et al.
Nature communications, 6, 6704-6704 (2015-04-08)
Metabolic homeostasis is regulated by the brain, but whether this regulation involves learning and memory of metabolic information remains unexplored. Here we use a calorie-based, taste-independent learning/memory paradigm to show that Drosophila form metabolic memories that help in balancing food
Tuula M Jyske et al.
Planta, 242(3), 613-629 (2015-06-25)
Phloem production and structural development were interlinked with seasonal variation in the primary and secondary metabolites of phloem. Novel microtechniques provided new perspectives on understanding phloem structure and chemistry. To gain new insights into phloem formation in Norway spruce (Picea
Douglas P Jasmer et al.
International journal for parasitology. Drugs and drug resistance, 14, 167-182 (2020-10-31)
In research focused on the intestine of parasitic nematodes, we recently identified small molecule inhibitors toxic to intestinal cells of larval Ascaris suum (nematode intestinal toxins/toxicants; "NITs"). Some NITs had anthelmintic activity across the phylogenetic diversity of the Nematoda. The
E Ciuchi et al.
Metabolism: clinical and experimental, 45(5), 611-613 (1996-05-01)
Red blood cell (RBC) concentrations of sorbitol and reduced glutathione (GSH) were evaluated in 29 type 11 diabetic subjects and eight normal controls. In erythrocytes from diabetic subjects, sorbitol levels were higher (18.7 +/- 1.33 v 11.2 +/- 0.7 nmol/g
J A Molina et al.
Journal of neural transmission (Vienna, Austria : 1996), 109(7-8), 1035-1044 (2002-07-12)
Thiamine is an essential cofactor for several important enzymes involved in brain oxidative metabolism, such as the alpha-ketoglutarate dehydrogenase complex (KGDHC), pyruvate-dehydrogenase complex (PDHC), and transketolase. Some investigators reported decreased thiamine-diphosphate levels and decreased activities of KGDHC, pyruvate-dehydrogenase complex and
Brigida Gallone et al.
Cell, 166(6), 1397-1410 (2016-09-10)
Whereas domestication of livestock, pets, and crops is well documented, it is still unclear to what extent microbes associated with the production of food have also undergone human selection and where the plethora of industrial strains originates from. Here, we
Hiroko Asahi et al.
BMC microbiology, 14, 167-167 (2014-06-26)
Malaria continues to be a devastating disease. The elucidation of factors inducing asexual growth versus arrest of Plasmodium falciparum can provide information about the development of the parasite, and may help in the search for novel malaria medication. Based on
Reddy Ranjith K Sama et al.
Journal of cellular physiology, 228(11), 2222-2231 (2013-04-30)
FUsed in Sarcoma/Translocated in LipoSarcoma (FUS/TLS or FUS) has been linked to several biological processes involving DNA and RNA processing, and has been associated with multiple diseases, including myxoid liposarcoma and amyotrophic lateral sclerosis (ALS). ALS-associated mutations cause FUS to
Fidaa Bouezzedine et al.
Virology, 481, 34-42 (2015-03-15)
Hepatitis B virus (HBV) infection is a major public health problem. Recently, the human liver bile acid transporter Na(+)/taurocholate cotransporting polypeptide (NTCP) has been identified as an HBV specific receptor. NTCP expression is known to be strongly regulated by IL-6.
Feng Li et al.
STAR protocols, 2(2), 100392-100392 (2021-04-16)
Transposon insertion sequencing (TIS) is a highly effective method used with bacteria to identify genes important for growth in any condition of interest. Previously, we adapted this method to identify essential genes of the yeast Schizosaccharomyces pombe. Here, we describe
A Patrizi et al.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 147(6 Suppl 1), 1-8 (2013-01-18)
Pityriasis alba (PA) is a skin disorder characterized by finely scaly, hypopigmented patches, typical of childhood, that also represents an atopic dermatitis (AD) minor sign according to Hanifin and Rajka criteria. It may be isolated or associated with AD representing
Meseret Ashenafi et al.
Molecular and cellular biochemistry, 400(1-2), 9-15 (2014-10-31)
Recently, we showed that the fused chorismate-utilizing enzyme from the antibiotic-producing soil bacterium Streptomyces venezuelae is an anthranilate synthase (designated SvAS), not a 2-amino-2-deoxyisochorismate (ADIC) synthase, as was predicted based on its amino acid sequence similarity to the phenazine biosynthetic
Ho-Youn Kim et al.
Plant science : an international journal of experimental plant biology, 231, 30-39 (2015-01-13)
During ripening fruits undergo several physiological and biochemical modifications that influence quality-related properties, such as texture, color, aroma and taste. We studied the differences in ethylene and sugar metabolism between two genetically related Japanese plum cultivars with contrasting ripening behaviors.
Abishek Muralidhar et al.
Plant, cell & environment, 38(8), 1514-1527 (2014-12-30)
Aquatic organisms are often exposed to dramatic changes in salinity in the environment. Despite decades of research, many questions related to molecular and physiological mechanisms mediating sensing and adaptation to salinity stress remain unanswered. Here, responses of Vaucheria erythrospora, a
Shigekatsu Suzuki et al.
Genome biology and evolution, 7(6), 1533-1545 (2015-05-24)
Many algal groups acquired complex plastids by the uptake of green and red algae through multiple secondary endosymbioses. As a result of gene loss and transfer during the endosymbiotic processes, algal endosymbiont nuclei disappeared in most cases. However, chlorarachniophytes and
Mohamed Hazman et al.
Journal of experimental botany, 66(11), 3339-3352 (2015-04-16)
Salinity stress represents a global constraint for rice, the most important staple food worldwide. Therefore the role of the central stress signal jasmonate for the salt response was analysed in rice comparing the responses to salt stress for two jasmonic
Vahideh Mahdavi et al.
Analytical biochemistry, 478, 65-72 (2015-03-15)
Diazinon insecticide is widely applied throughout rice (Oryza sativa L.) fields in Iran. However, concerns are now being raised about its potential adverse impacts on rice fields. In this study, a time-course metabolic change in rice plants was investigated after
Page 1 of 13