Andrea Groß et al.
Bioorganic & medicinal chemistry, 23(14), 4050-4055 (2015-03-25)
The chemokine receptor CXCR4 belongs to the family of seven-transmembrane G-protein coupled receptors (GPCRs). It is activated by its natural ligand SDF-1α. In addition, CXCR4, along with CCR5, serve as coreceptors during HIV-1 entry into its target cell. Recently, we