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Showing 31-60 of 137 results for "t3824" within Papers
Detection of mutations in the tyrosinase gene in a patient with type IA oculocutaneous albinism.
R A Spritz et al.
The New England journal of medicine, 322(24), 1724-1728 (1990-06-14)
Neda Rafat et al.
Biosensors, 11(11) (2021-11-26)
A novel, integrated experimental and modeling framework was applied to an inhibition-based bi-enzyme (IBE) electrochemical biosensor to detect acetylcholinesterase (AChE) inhibitors that may trigger neurological diseases. The biosensor was fabricated by co-immobilizing AChE and tyrosinase (Tyr) on the gold working
Wangsa T Ismaya et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 67(Pt 5), 575-578 (2011-05-06)
Tyrosinase catalyzes the conversion of tyrosine to dihydroxyphenylalanine quinone, which is the main precursor for the biosynthesis of melanin. The enzyme from Agaricus bisporus, the common button mushroom, was purified and crystallized in two different space groups. Crystals belonging to
Zong-Ping Zheng et al.
Fitoterapia, 84, 242-247 (2012-12-25)
The twigs of Cudrania tricuspidata were found to show strong tyrosinase inhibitory activity, and further detailed component analysis resulted in the isolation of a new flavanol glucoside, (2S,3S)-2,3-trans-dihydromorin-7-O-β-d-glucoside (1), plus twenty-seven known compounds (2-28). Their structures were elucidated on the
Tomas F M Kuijpers et al.
The FEBS journal, 280(23), 6184-6195 (2013-10-12)
Sulfite salts are widely used as antibrowning agents in food processing. Nevertheless, the exact mechanism by which sulfite prevents enzymatic browning has remained unknown. Here, we show that sodium hydrogen sulfite (NaHSO3) irreversibly blocks the active site of tyrosinase from
Separation, purification, and properties of two tyrosinases from hamster melanoma.
S H POMERANTZ
The Journal of biological chemistry, 238, 2351-2357 (1963-07-01)
Hyun-E Lee et al.
Die Pharmazie, 68(3), 212-216 (2013-04-06)
Melanin plays major a role in pigmentation of hair, eyes, and skin in mammals. In this study, the inhibitory effects of MMS 1001 on alpha-MSH-stimulated melanogenesis were investigated in B16F10 melanoma cells. MMS 1001 did not show cytotoxic effects up
Aminu Muhammad et al.
Natural product communications, 8(10), 1435-1437 (2013-12-21)
The stem bark extracts of Bauhinia rufescens Lam. (Fabaceae) yielded 6-methoxy-7-methyl-8-hydroxydibenz[b,f]oxepin, alpha-amyrin acetate, beta-sitosterol 3-O-beta-D-xylopyranoside, 4-(2'-Hydroxyphenethyl)-5-methoxy-2-methylphenol, menisdaurin and sequoyitol. Their structures were determined using spectroscopic methods and comparisons with the literature data. For the antimicrobial assay Gram-positive and Gram-negative bacterial
R Martínez-Arias et al.
Pigment cell research, 13(6), 467-470 (2001-01-12)
The sequence of the tyrosinase (Tyr) gene coding tracts has been obtained for the gorilla (Gorilla gorilla gorilla). The five exons of the gene were sequenced in three gorillas and in a normally pigmented human. The tyrosinase gene has been
Tyrosinase: a comprehensive review of its mechanism.
A Sánchez-Ferrer et al.
Biochimica et biophysica acta, 1247(1), 1-11 (1995-02-22)
Shilpi Goenka et al.
Molecules (Basel, Switzerland), 25(16) (2020-08-13)
Previous studies have reported that estrogen hormone promotes melanogenesis while progesterone inhibits it. A selective estrogen receptor modulator (SERM), tamoxifen, has been shown to promote melanogenesis; however, to date, there have been no reports on the effects of a selective
Jakub Zdarta et al.
Biotechnology advances, 37(7), 107401-107401 (2019-05-28)
In the modern era, the use of sustainable, environmentally friendly alternatives for removal of recalcitrant pollutants in streams resulting from industrial processes is of key importance. In this context, biodegradation of phenolic compounds, pharmaceuticals and dyes in wastewater by using
Xiaoyu Chen et al.
Oxidative medicine and cellular longevity, 2012, 534934-534934 (2013-01-11)
The chemotherapeutical treatment is very limited for malignant melanoma, a highly lethal disease occurs globally. Natural products derived from traditional Chinese medicine licorice are attractive in quest new treatments due to their anti-tumor activities. A new dietary flavonoid isoliquiritigenin (ISL)
Sung Jin Bae et al.
Bioscience, biotechnology, and biochemistry, 77(1), 65-72 (2013-01-08)
We synthesized a novel series of (E)-2-((substituted phenyl)diazenyl)phenyl 4-methylbenzenesulfonate derivatives (2 and 3) and (E)-2-((substituted phenyl)diazenyl)phenol derivatives (4 and 5), and conducted an evaluation in order to determine their inhibitory effects on mushroom tyrosinase, with the aim of discovering a
Kazuya Murata et al.
Natural product communications, 9(2), 185-188 (2014-04-03)
In our research program for discovering novel skin-whitening materials, screening of extracts from flowers of some Prunus species was performed using an anti-tyrosinase assay. Among the tested plants, the flowers of P. persica showed the most potent inhibitory activity. In
L M C Silva et al.
Environmental technology, 35(5-8), 1012-1017 (2014-03-22)
A simple and inexpensive biosensor based on lyophilized mushroom tissue (Agaricus bisporus) was developed for amperometric determination of phenol. This fungi tissue contains tyrosinase (EC 1.14.18.1) enzyme that catalysis two sequential oxidation reactions with phenolic substrates. Both reactions involve molecular
Yun-Mi Jeong et al.
Bioscience, biotechnology, and biochemistry, 77(1), 119-125 (2013-01-08)
To our knowledge, there is no report that directly shows an inhibitory effect of ginsenoside on melanin synthesis in B16 melanoma cells. Hence, we investigated whether the aglycone of Rh(4) (A-Rh4) inhibits melanin synthesis in B16 melanoma cells, and determined
Ampai Phrutivorapongkul et al.
Pakistan journal of pharmaceutical sciences, 26(6), 1071-1076 (2013-11-06)
The flowers of African marigold (Tagetes erecta L), a medicinal plant widely cultivated in Thailand, were subjected to evaluation for total phenolics, DPPH scavenging and thiobarbituric acid-reactive substance (TBARs) assays as well as tyrosinase inhibitory activity. In preliminary studies, the
B S Kwon et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(21), 7473-7477 (1987-11-01)
Screening of a lambda gt11 human melanocyte cDNA library with antibodies against hamster tyrosinase (monophenol, L-dopa:oxygen oxidoreductase, EC 1.14.18.1) resulted in the isolation of 16 clones. The cDNA inserts from 13 of the 16 clones cross-hybridized with each other, indicating
Hye-Eun Kim et al.
BMB reports, 45(12), 724-729 (2012-12-25)
In this study, we evaluated the anti-melanogenesis effects of Caffeoylserotonin (CaS) in B16 melanoma cells. Treatment with CaS reduced the melanin content and tyrosinase (TYR) activity in B16 melanoma cells in a dose-dependent manner. CaS inhibited the expression of melanogenesis-related
B Bouchard et al.
The Journal of experimental medicine, 169(6), 2029-2042 (1989-06-01)
A distinguishing characteristic of cells of the melanocyte lineage is the expression of the melanosomal enzyme tyrosinase that catalyzes the synthesis of the pigment melanin. A tyrosinase cDNA clone, designated BBTY-1, was isolated from a library constructed from the pigmented
Jingsong Cao et al.
Molecular immunology, 57(2), 263-273 (2013-11-12)
Recently, considerable interest has been focused on immunostimulants to reduce diseases in crab aquaculture. However, information regarding to the related immune-enhancing proteins in crabs is not available yet. In this study, rhubarb polysaccharides were tested for enhancement of the immune
Epidermal growth factor and epidermal growth factor signaling attenuate laser-induced melanogenesis.
Woo Jin Yun et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 39(12), 1903-1911 (2013-10-18)
Epidermal growth factor (EGF) is a peptide that promotes cell growth by binding to its receptor (EGFR) on the cell surface. EGF has been used in cosmetics to whiten the skin and for the prevention of postinflammatory hyperpigmentation (PIH), presumably
Su-Tze Chou et al.
International journal of molecular sciences, 14(9), 19186-19201 (2013-09-21)
Essential oils extracted from aromatic plants exhibit important biological activities and have become increasingly important for the development of aromatherapy for complementary and alternative medicine. The essential oil extracted from Cinnamomum cassia Presl (CC-EO) has various functional properties; however, little
Ahmad A Al Robaee et al.
Autoimmunity, 53(8), 459-466 (2020-10-22)
Regulation of melanogenesis by tyrosinase has now become an attractive approach for treatment of vitiligo but still the role of tyrosinase in the induction of depigmentation remains largely unexplored. This study was explored the role of tyrosinase in the induction
Patrick Sulem et al.
Nature genetics, 39(12), 1443-1452 (2007-10-24)
Hair, skin and eye colors are highly heritable and visible traits in humans. We carried out a genome-wide association scan for variants associated with hair and eye pigmentation, skin sensitivity to sun and freckling among 2,986 Icelanders. We then tested
Ponsawan Netcharoensirisuk et al.
Molecules (Basel, Switzerland), 26(19) (2021-10-14)
Despite its classification as a non-life-threatening disease, increased skin pigmentation adversely affects quality of life and leads to loss of self-confidence. Until now, there are no recommended remedies with high efficacy and human safety for hyperpigmentation. This study aimed to
Shilpi Goenka et al.
Biomedicines, 8(10) (2020-10-18)
CMT-308 is a nonantimicrobial chemically-modified tetracycline (CMT), which we have previously shown exhibits antifungal activity and pleiotropic anti-inflammatory activities, including inhibition of the enzymatic activity of matrix metalloproteinases (MMPs). Based on its chemical structure, we hypothesized that CMT-308 could inhibit
Yang Yao et al.
International journal of molecular sciences, 12(10), 7048-7058 (2011-11-11)
Phenolic acids have been identified in a variety of legumes including lima bean, broad bean, common bean, pea, jack bean, goa bean, adzuki bean, hyacinth bean, chicking vetch, garbanzo bean, dral, cow bean, rice bean, mung bean and soybean. The
Dae Hyun Shin et al.
Pharmaceutical biology, 51(11), 1467-1476 (2013-10-11)
Sophora flavescens Ait. (Leguminosae) has been proposed as a new whitening agent for cosmetics, because it has a strong ability to inhibit tyrosinase, a key enzyme in the formation of melanin. We conducted a study to determine whether ethanol extract
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