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Showing 1-30 of 517 results for "T4885" within Papers
Valentino Ruggieri et al.
BMC plant biology, 14, 337-337 (2014-12-04)
Genome Wide Association Studies (GWAS) have been recently used to dissect complex quantitative traits and identify candidate genes affecting phenotype variation of polygenic traits. In order to map loci controlling variation in tomato marketable and nutritional fruit traits, we used
Narcy Arizmendi et al.
Respiratory research, 15, 71-71 (2014-06-28)
Pulmonary fibrotic diseases induce significant morbidity and mortality, for which there are limited therapeutic options available. Rac2, a ras-related guanosine triphosphatase expressed mainly in hematopoietic cells, is a crucial molecule regulating a diversity of mast cell, macrophage, and neutrophil functions.
Fei Xu et al.
FEMS microbiology letters, 358(1), 98-105 (2014-07-24)
This study investigated inactivation of bacteria with ultraviolet light A irradiation in combination with vitamin K3 as a photosensitizer. Six bacteria including Bacillus cereus, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis, Klebsiella pneumoniae, and Escherichia coli suspended in vitamin K3 aqueous
Keyvan Amirshahrokhi et al.
Chemico-biological interactions, 225, 63-69 (2014-12-06)
Excessive ethanol ingestion causes gastric mucosal damage through the inflammatory and oxidative processes. The present study was aimed to evaluate the protective effect of thalidomide on ethanol-induced gastric mucosal damage in mice. The animals were pretreated with vehicle or thalidomide
Samuel Okwudili Onoja et al.
Journal of basic and clinical physiology and pharmacology, 26(5), 465-470 (2015-04-29)
Daniella oliveri is a deciduous plant that is commonly found in savanna and open grassland. Various parts of the plant is used by herbalist in the management of different ailments. The present study aims at investigating the hepatoprotective and antioxidant
Fidan O Can et al.
Journal of food protection, 77(10), 1723-1731 (2014-10-07)
Cheese is a ready-to-eat food that may be contaminated on the surface by undesirable spoilage and pathogenic microorganisms during production, packaging, and postpackaging processes. Penicillium roqueforti is commonly found on cheese surfaces at refrigeration temperatures and is one of the
Hong-Mei Li et al.
Journal of Asian natural products research, 17(7), 761-766 (2015-01-16)
Two new abietane diterpene glycosides, wilfordosides A (1) and B (2), were isolated from the roots of Tripterygium wilfordii. The structures of compounds 1 and 2 were established using spectroscopic methods including extensive 1D and 2D NMR analysis, in combination
Joan Eilstein et al.
Archives of toxicology, 88(9), 1681-1694 (2014-03-25)
Skin function is not limited to a physical barrier. According to its total surface area, it is also considered as an extra-hepatic metabolizing organ. In vitro engineered human skins have been developed to replace limited ex vivo normal human skin
Jie Zhang et al.
PloS one, 9(9), e107478-e107478 (2014-09-13)
To interrogate why redox homeostasis and glutathione S-transferase P (GSTP) are important in regulating bone marrow cell proliferation and migration, we isolated crude bone marrow, lineage negative and bone marrow derived-dendritic cells (BMDDCs) from both wild type (WT) and knockout
Rongfang Liu et al.
Biochemical pharmacology, 95(4), 290-300 (2015-04-22)
The adenosine receptor subfamily includes four subtypes: the A1, A2A, A2B and A3 receptors, which all belong to the superfamily of G protein-coupled receptors (GPCRs). The adenosine A2B receptor is the least investigated of the adenosine receptors, and the molecular
Amira Zayed et al.
The Journal of dermatological treatment, 25(3), 223-225 (2012-04-13)
Despite several therapeutic modalities, acanthosis nigricans (AN) remains a difficult dermatosis to treat. This study aims to test the safety and efficacy of trichloroacetic acid (TCA) as a chemical peel in the treatment of AN in a random sample of
Divyabharathi Chepyala et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 980, 48-54 (2015-01-16)
Recently, colistin has become one of the most important drugs for treating infections caused by multidrug-resistant Gram-negative bacteria. Therapeutic drug monitoring is recommended to ensure the safety and efficacy of colistin and to improve clinical outcomes. This study developed an
Poonam Goswami et al.
Environmental toxicology and pharmacology, 40(1), 122-139 (2015-06-27)
The present study was conducted to investigate the effect of rotenone on astrocytes activation, their viability and its effect on neuronal death in different brain regions. Rotenone was injected in rat brain by intracerebroventricularly (bilateral) route at dose of 6
J Efraim Oosterink et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 998-999, 106-113 (2015-07-22)
Methionine, homocysteine, vitamins B6, B12, B9, and their metabolites are crucial co-factors and substrates for many basic biological pathways including one-carbon metabolism, and they are particularly important for brain function and development and epigenetic mechanisms. These are essential nutrients that
Songsong Zhu et al.
Cell transplantation, 23(6), 715-727 (2014-04-26)
In cartilage tissue engineering using stem cells, it is important to stimulate proliferation and control the differentiation of stem cells to specific lineages. Here we reported a combined technique for articular cartilage repair, consisting of bone marrow mesenchymal stem cells
Phanuel Saroni Arwa et al.
Journal of ethnopharmacology, 174, 410-418 (2015-09-01)
Garcinia brasiliensis, a plant native to the Brazilian Amazon Rainforest, is used in traditional medicine to treat inflammation of the urinary tract, peptic ulcers, arthritis and other conditions. The purposes of this study were to analyze the chemical constituents of
Trichloroacetic acid.
IARC monographs on the evaluation of carcinogenic risks to humans, 63, 291-314 (1995-01-01)
Vinodkumar B Pillai et al.
Nature communications, 6, 6656-6656 (2015-04-15)
Honokiol (HKL) is a natural biphenolic compound derived from the bark of magnolia trees with anti-inflammatory, anti-oxidative, anti-tumour and neuroprotective properties. Here we show that HKL blocks agonist-induced and pressure overload-mediated, cardiac hypertrophic responses, and ameliorates pre-existing cardiac hypertrophy, in
C A Whipple et al.
British journal of cancer, 111(8), 1625-1633 (2014-08-15)
Melanoma, the most lethal form of skin cancer, is responsible for over 80% of all skin cancer deaths and is highly metastatic, readily spreading to the lymph nodes or metastasising to other organs. The frequent genetic mutation found in metastatic
Sumonto Mitra et al.
Environmental toxicology, 30(12), 1393-1405 (2014-06-05)
Tributyltin (TBT), a well-known endocrine disruptor, is an omnipresent environmental pollutant and is explicitly used in many industrial applications. Previously we have shown its neurotoxic potential on cerebral cortex of male Wistar rats. As the effect of TBT on other
Jonathan I Silverberg et al.
Journal of drugs in dermatology : JDD, 11(10), 1228-1230 (2012-11-09)
Squaric acid dibutyl ester (SADBE) is a commonly used treatment for verruca vulgaris of childhood. Few studies, however, have examined the role of SADBE in combination with other topical therapies for warts. We sought to determine if trichloroacetic acid 50%
Monique Michels et al.
Molecular medicine (Cambridge, Mass.), 21, 219-226 (2015-03-31)
Sepsis-associated encephalopathy (SAE) is associated with an increased rate of morbidity and mortality. It is not understood what the exact mechanism is for the brain dysfunction that occurs in septic patients, but brain inflammation and oxidative stress are a possible
Hyeong-Geug Kim et al.
World journal of gastroenterology, 20(42), 15703-15714 (2014-11-18)
To evaluate protective effects of Chunggan extract (CGX), a traditional herbal formula, under 4 wk of alcohol consumption-induced liver injury. Male Sprague-Dawley Rats were orally administered 30% ethanol daily for 4 wk with or without CGX. The pharmaceutical properties were
Pavel Michal et al.
Neurochemical research, 40(10), 2068-2077 (2014-05-14)
We have found earlier that changes in membrane cholesterol content have distinct impact on signaling via the M1, M2, or M3 receptors expressed in CHO cells (CHO-M1 through CHO-M3). Now we investigated whether gradual changes in membrane cholesterol exerts differential
Fakhrozaman Pezeshkpoor et al.
Journal of drugs in dermatology : JDD, 11(11), e66-e69 (2012-11-09)
Common warts caused by the human papillomavirus (HPV) are considered to be the most common infectious skin disease. No individual treatment for common warts is effective as monotherapy in eradicating the lesions. The aim of this study is to evaluate
Ying Wang et al.
Diabetes, 63(8), 2643-2655 (2014-03-13)
After diabetes, the heart has a singular reliance on fatty acid (FA) for energy production, which is achieved by increased coronary lipoprotein lipase (LPL) that breaks down circulating triglycerides. Coronary LPL originates from cardiomyocytes, and to translocate to the vascular
Amitava Khan et al.
Free radical research, 49(10), 1173-1186 (2015-05-23)
Radioprotective action of gossypetin (GTIN) against gamma (γ)-radiation-induced oxidative stress in liver was explored in the present article. Our main aim was to evaluate the protective efficacy of GTIN against radiation-induced alteration of liver in murine system. To evaluate the
Mohamed S Othman et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 69, 175-181 (2014-04-23)
Mercury (Hg) is the third most dangerous heavy metal after arsenic and lead. Mercury's toxicity brings serious risks to health through negative pathological and biochemical effects. The study was designed to investigate the possible protective role of berberine (BN) in
John W Loughney et al.
Analytical biochemistry, 461, 49-56 (2014-05-21)
Bovine serum albumin (BSA) is a major component of fetal bovine serum (FBS), which is commonly used as a culture medium during vaccine production. Because BSA can cause allergic reactions in humans the World Health Organization (WHO) has set a
Zidong Liu et al.
Environmental toxicology and chemistry, 34(9), 2033-2040 (2015-04-23)
Microcystin-LR (MC-LR) has the potential to disturb thyroid hormone homeostasis, but little is known about the underlying mechanisms of MC-LR in fish. In the present study, juvenile Chinese rare minnows (Gobiocypris rarus) were exposed to various concentrations of MC-LR (0 µg/L
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