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Showing 1-30 of 190 results for "T7004" within Papers
Kyly C Whitfield et al.
The Journal of nutrition, 150(6), 1461-1469 (2020-03-27)
Except for low thiamin content, little is known about vitamins or macronutrients in milk from Cambodian mothers, and associations among milk nutrients. We measured fat-soluble vitamins (FSVs) and water-soluble vitamins (WSVs), and macronutrients, and explored internutrient associations in milk from
Yukie Tsugoshi et al.
Chemico-biological interactions, 327, 109148-109148 (2020-06-09)
We investigated the inhibitory effects of 13 organophosphate esters (OPEs) and hydrolytic metabolites on the carboxylesterase activity of rat liver microsomes in vitro in order to examine whether there might be a potential impact on human health, and to elucidate
Sevcan Aydin et al.
Bioresource technology, 318, 123965-123965 (2020-09-06)
Membrane bioreactor systems face an inevitable challenge that is biofouling, which not only hinders the operation of the system, but also poses an environmental and medical concern caused by the increased antibiotic resistance in bacterial biofilms. This study investigates the
Doris Hellerschmied et al.
Molecular biology of the cell, 30(17), 2296-2308 (2019-06-06)
In eukaryotic cells, organelle-specific protein quality control (PQC) is critical for maintaining cellular homeostasis. Despite the Golgi apparatus being the major protein processing and sorting site within the secretory pathway, how it contributes to PQC has remained largely unknown. Using
Iyare Izevbaye et al.
The Journal of molecular diagnostics : JMD, 22(2), 208-219 (2019-11-22)
Myeloid neoplasms are a heterogeneous group of neoplasms including acute myeloid leukemia (AML), myeloproliferative neoplasms, myelodysplastic syndrome, and myeloproliferative neoplasms/myelodysplastic syndrome. Genetic abnormalities are used as diagnostic, prognostic, and predictive biomarkers in patients with these diseases. Herein, we describe the
Jia Li et al.
Environmental monitoring and assessment, 192(6), 336-336 (2020-05-10)
Estuary is an important route for the transport of terrestrial contaminants to the ocean. Its unique hydrodynamic properties may influence the fate and distribution of pollutants. Previous studies have shown that severe pollution because of antibiotics has occurred in many
Han-Shin Kim et al.
Journal of hazardous materials, 402, 123501-123501 (2020-07-28)
A membrane bioreactor (MBR) integrates process such as membrane filtration and biological treatment of activated sludge. However, organic, inorganic and biological matters cause membrane fouling, which seriously affects membrane performance. The goal of this study was to evaluate the biofouling
Doyoung Kim et al.
Nature medicine, 26(2), 236-243 (2020-01-22)
Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DiHS/DRESS) is a potentially fatal multiorgan inflammatory disease associated with herpesvirus reactivation and subsequent onset of autoimmune diseases1-4. Pathophysiology remains elusive and therapeutic options are limited. Cases refractory to corticosteroid therapy
Lakshmi Priya Pasari et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 112, 108629-108629 (2019-02-25)
Acute pancreatitis (AP) is an exocrine dysfunction of the pancreas where oxidative stress and inflammatory cytokines play a key role in induction and progression of the disease. Studies have demonstrated that antioxidant phytochemicals have been effective in improving pancreatitis condition
Jaswant Singh et al.
Food chemistry, 327, 127080-127080 (2020-05-27)
A hydrazone based Schiff base (SB) has been synthesized and investigated for the detection, quantification and degradation of selective organophosphates (i.e diethyl chlorophosphate, diethyl cyanophosphonate, tris (2-chloroethyl) phosphate and dichlorvos). The organophosphates (OPs) form a covalent bond with -OH groups
Sabina Lachowicz et al.
Antioxidants (Basel, Switzerland), 8(9) (2019-09-22)
The aim of the present work was to evaluate for content of phytochemicals (monophosphate nucleotides, free amino acids, polyphenols), and for anti-microbiological, anti-diabetic (ability to inhibit pancreatic lipase, α-glucosidase, and α-amylase), and antioxidant activities in seven selected fruit and fruit
Yashiro Kazuya et al.
American journal of physiology. Endocrinology and metabolism, 306(10), E1110-E1119 (2014-03-20)
Capsiate is known to increase whole body oxygen consumption possibly via the activation of uncoupling processes, but its effect at the skeletal muscle level remains poorly documented and conflicting. To clarify this issue, gastrocnemius muscle function and energetics were investigated
Ke Li et al.
Journal of chromatography. A, 1614, 460730-460730 (2019-12-10)
A simple and ecofriendly sample preparation method was developed for quantifying fluoroquinolone (FQ) antibiotics in surface water. Seventeen combinations of monoterpenes (menthol, thymol, and camphor), fatty acids (heptanoic, octanoic, nonanoic, and decanoic acids), and a benzoate ester (salol) were utilized
Ryan De Sotto et al.
Water research, 182, 115991-115991 (2020-08-03)
A critical challenge in the application of membrane bioreactors (MBR) for domestic wastewater treatment is its high energy consumption caused by continuous aeration for biofouling control. To reduce energy consumption and mitigate fouling in membranes, alternative configurations using dynamic shear-enhanced
Anna Socha et al.
Cell reports, 32(1), 107850-107850 (2020-07-09)
The Fanconi anemia (FA) pathway repairs DNA interstrand crosslinks (ICLs). Many FA proteins are recruited to ICLs in a timely fashion so that coordinated repair can occur. However, the mechanism of this process is poorly understood. Here, we report the
Sebastian Hoffmann et al.
The EMBO journal, 39(20), e105505-e105505 (2020-09-19)
Centromeres are built on repetitive DNA sequences (CenDNA) and a specific chromatin enriched with the histone H3 variant CENP-A, the epigenetic mark that identifies centromere position. Here, we interrogate the importance of CenDNA in centromere specification by developing a system
Jamie Cummins et al.
PloS one, 14(6), e0218661-e0218661 (2019-06-25)
An increasing body of evidence shows the importance of accommodating relational information within implicit measures of psychological constructs. Whereas relational variants of the Implicit Association Test (IAT) have been proposed in the past, we put forward the Truth Misattribution Procedure
Xianlong Ye et al.
International journal of biological macromolecules, 135, 362-372 (2019-05-28)
Fibroblast growth factor 21 (FGF-21) is an important regulator in glycolipid metabolism that is a promising drug candidate for treatment of diabetes and obesity. However, the productivity of recombinant hFGF-21 (rhFGF-21) in Escherichia coli (E. coli) is relatively low, which
Wu Minhui et al.
The Science of the total environment, 686, 97-106 (2019-06-10)
Propranolol (PRO) is widely detected in the aquatic environment and proved to be detrimental to multifarious aquatic organisms. In view of some virtues of sulfate radicals than hydroxyl radicals, advanced oxidation technologies that involve the activation of peroxymonosulfate (PMS) have
Huaqing Cui et al.
Experimental and therapeutic medicine, 20(4), 3878-3887 (2020-08-29)
Tetramethylpyrazine (TMP) has neuroprotective effects in the pathogenesis of some human diseases, such as Parkinson's disease. The present study aimed to investigate the role of TMP in isoflurane-induced cognitive dysfunction in rats, and further identify the mechanisms involved in the
Song-Lin Ding et al.
Cell reports, 31(7), 107648-107648 (2020-05-21)
Subicular regions play important roles in spatial processing and many cognitive functions, and these are mainly attributed to the subiculum (Sub) rather than the prosubiculum (PS). Using single-cell RNA sequencing, we identify 27 transcriptomic cell types residing in sub-domains of
Nannan Zhao et al.
Journal of agricultural and food chemistry, 68(42), 11694-11701 (2020-09-02)
Animal protein supplement feeds (APFs) are important raw feed materials for livestock. APFs might be susceptible to organophosphate esters (OPEs) but have not been paid attention yet. In the present study, animal-derived (meat meal, feather meal, and blood meal) and
Lu Yang et al.
Environment international, 135, 105306-105306 (2019-12-28)
Pharmaceuticals and personal care products (PPCPs) are recognized as one emerging group of environmental contaminants, capturing worldwide attention. These chemicals, closely connected to anthropogenic activities, are mainly transported through aquatic environments and reach coastal areas, eventually entering ocean offshore. Thus
Emilia S Jahangir et al.
Cellulose (London, England), 27(5), 2803-2816 (2020-04-01)
Low consistency (LC) refining of (chemi-)thermomechanical pulp (TMP) provides an energy efficient alternative to high consistency refining for pulp property development. However, the benefit of LC refining is often limited by excessive fibre shortening, lower tear strength and a reduction
Donald B Kohn et al.
Nature medicine, 26(2), 200-206 (2020-01-29)
Chronic granulomatous disease (CGD) is a rare inherited disorder of phagocytic cells1,2. We report the initial results of nine severely affected X-linked CGD (X-CGD) patients who received ex vivo autologous CD34+ hematopoietic stem and progenitor cell-based lentiviral gene therapy following
Jnyandeep Hazarika et al.
Journal of applied toxicology : JAT, 40(3), 434-443 (2020-01-01)
Chlorpyrifos (CPF) is a widely used pesticide effective against a large number of target pests, which is used by farmers to protect food crops. Based on earlier epidemiologic reports, which indicate that CPF might interfere with the progesterone signaling pathway
Amaia Ercilla et al.
Cell reports, 30(7), 2416-2429 (2020-02-23)
It has been long assumed that normally leading strand synthesis must proceed coordinated with the lagging strand to prevent strand uncoupling and the pathological accumulation of single-stranded DNA (ssDNA) in the cell, a dogma recently challenged by in vitro studies in
Ángeles Ortega et al.
The Journal of nutritional biochemistry, 22(6), 595-604 (2010-10-26)
Dietary nucleotides (NTs) have an important role in cellular and humoral immunity, intestinal growth, differentiation and recovery from tissue damage. Nucleosides (NSs) are the best-absorbed chemical form of NTs in the intestinal epithelium. The aim of this study was to
Vinicius Miessler de Andrade Carvalho et al.
Cell reports, 32(8), 108061-108061 (2020-08-28)
The internal representation of sensory information via coherent activation of specific pathways in the nervous system is key to appropriate behavioral responses. Little is known about how chemical stimuli that elicit instinctive behaviors lead to organized patterns of activity in
Erica Sequeira et al.
Marine drugs, 18(7) (2020-07-28)
Emerging literature suggests that after a stroke, the peri-infarct region exhibits dynamic changes in excitability. In rodent stroke models, treatments that enhance excitability in the peri-infarct cerebral cortex promote motor recovery. This increase in cortical excitability and plasticity is opposed
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