Search Within
v900437
Applied Filters:
Keyword:'v900437'
Showing 1-30 of 99 results for "v900437" within Papers
Zhuzhong Cheng et al.
Nuclear medicine communications, 36(9), 914-921 (2015-05-15)
(18)F-Fluorodeoxyglucose ((18)F-FDG), (18)F-fluoro-3'-deoxy-3'-L-fluorothymidine ((18)F-FLT), (18)F-fluoromisonidazole ((18)F-FMISO), and (18)F-AlF-NOTA-PRGD2 ((18)F-RGD) are all commonly used PET tracers for tumor diagnosis based on different mechanisms of tissue uptake. This study compared the ex-vivo biodistribution and PET/computed tomography (CT) imaging studies of these four
Bleomycin, an antibiotic that removes thymine from double-stranded DNA.
W E Müller et al.
Progress in nucleic acid research and molecular biology, 20, 21-57 (1977-01-01)
R Ivarie
Nucleic acids research, 15(23), 9975-9983 (1987-12-10)
Evidence is summarized showing that thymine methyls are as important in the recognition of specific sequences by proteins as are the more widely recognized hydrogen bonding sites of bases in the major groove (1). Strongest evidence has come from experiments
Ming Fan et al.
Macromolecular bioscience, 14(11), 1521-1527 (2014-09-03)
Biopolymer-based gel scaffolds have great potential in the field of tissue regenerative medicine. In this work, a nanostructured biopolymer gel scaffold via specific pairing of functionalized nucleobases was developed for specifically targeted drug delivery and in vitro osteogenesis. The biopolymer
K D Fulfer et al.
The Journal of chemical physics, 142(22), 224310-224310 (2015-06-15)
High-resolution photoelectron spectra of the gas phase pyrimidine-type nucleobases, thymine, uracil, and cytosine, were collected using synchrotron radiation over the photon energy range 17 ≤ hν ≤ 150 eV. These data provide the highest resolution photoelectron spectra of thymine, uracil
Elizabeth Choe et al.
mBio, 5(4), e01182-e01114 (2014-07-06)
Salmonella has been of interest in cancer research due to its intrinsic ability to selectively target and colonize within tumors, leading to tumor cell death. Current research indicates promising use of Salmonella in regular administrations to remove tumors in mouse
Ming Ni et al.
Journal of pharmaceutical and biomedical analysis, 78-79, 129-135 (2013-03-12)
To study in vivo activities of dihydropyrimidine dehydrogenase, dihydropyrimidinase, and ureidoproprionase, a sensitive, accurate, selective and precise method for the determination of the endogenous pyrimidine thymine (THY) and its successive metabolites dihydrothymine (DHT) and β-ureidoisobutyric (UIB) acid in human plasma
Huiying Song et al.
Journal of chromatography. A, 1369, 83-91 (2014-12-03)
An intrinsic performance comparison is made of the reduction in analysis time that can be obtained when switching from HPLC to UHPLC column formats in HILIC and reversed-phase conditions. A detailed overview of the packing characteristics of both stationary phase
[Genetic regulation of deoxyribose metabolism correlated with thymine requirement of Escherichia coli].
T Okada
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 17(6), 449-460 (1972-06-01)
[Phage induction, filament formation and thymine deficiency death in Escherichia coli B].
H D Mennigmann
Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie. Originale, 198(1), 282-286 (1965-12-01)
Diogo Almeida et al.
Physical review letters, 110(2), 023201-023201 (2013-02-07)
Electron transfer in alkali-molecule collisions to gas phase thymine and uracil yielding H- formation is selectively controlled in the energy range between 5.3 and 66.1 eV. By tuning the collision energy, electron transfer from the alkali to partly deuterated thymine
Y Yang et al.
Journal of dental research, 92(6), 500-506 (2013-04-30)
Hypodontia, a tooth developmental disease, can affect chewing and pronunciation. Mutations in the ectodysplasin-A (EDA) gene can lead to both X-linked hypohidrotic ectodermal dysplasia (XLHED) and non-syndromic hypodontia (NSH). However, the mechanism by which these 2 related but different disorders
Yusuke Sato et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 29(1), 15-19 (2013-01-11)
We describe a competitive binding assay for the analysis of single-base mutation by using abasic site (AP site)-specific binding fluorescent ligands and masking ligands bound to the AP site in DNA duplexes. 2-Amino-5,6,7-trimethyl-1,8-naphthyridine (ATMND) can strongly bind to not only
Javier A Tello et al.
American journal of physiology. Endocrinology and metabolism, 305(1), E67-E77 (2013-05-02)
The human GnRH receptor (GNRHR1) has a specific set of properties with physiological and pharmacological influences not appropriately modeled in laboratory animals or cell-based systems. To address this deficiency, we have generated human GNRHR1 knock-in mice and described their reproductive
Hongying Liu et al.
Biosensors & bioelectronics, 71, 249-255 (2015-04-29)
A triple-signal amplification strategy was proposed for highly sensitive and selective detection of thymine DNA glycosylase (TDG) by coupling a dendrimer-like DNA label with the electrochemical method and quantum dots (QDs) tagging. The DNA-QDs dendrimer-like superstructure was designed by DNA
Omar Ali et al.
Clinical epigenetics, 7, 12-12 (2015-03-26)
The prevalence of chronic diseases such as cancer, type 2 diabetes, metabolic syndrome (MetS), and cardiovascular disease increases with age in all populations. Epigenetic features are hypothesized to play important roles in the pathophysiology of age-associated diseases, but a map
Adrienne P Stephenson et al.
Toxicology letters, 218(3), 299-307 (2013-01-09)
Manganese (Mn) is an essential trace element required for normal function and development. However, exposure to this metal at elevated levels may cause manganism, a progressive neurodegenerative disorder with neurological symptoms similar to idiopathic Parkinson's disease (IPD). Elevated body burdens
Zofia Iskierko et al.
Biosensors & bioelectronics, 74, 526-533 (2015-07-18)
A novel recognition unit of chemical sensor for selective determination of the inosine, renal disfunction biomarker, was devised and prepared. For that purpose, inosine-templated molecularly imprinted polymer (MIP) film was deposited on an extended-gate field-effect transistor (EG-FET) signal transducing unit.
Andrea Coletta et al.
Nucleic acids research, 41(22), 9977-9986 (2013-09-05)
Camptothecin (CPT) is a topoisomerase IB (TopIB) selective inhibitor whose derivatives are currently used in cancer therapy. TopIB cleaves DNA at any sequence, but in the presence of CPT the only stabilized protein-DNA covalent complex is the one having a
Bin Wang et al.
Natural product communications, 9(4), 471-472 (2014-05-30)
Investigation of the marine sponge Haliclona sp. led to the isolation of two new thyminenol derivatives, named cis-thyminenol (1) and trans-thyminenol (2). The structures of the new isolates were elucidated on the basis of extensive spectroscopic analysis.
Shu-ichi Nakano et al.
Nucleic acids research, 41(18), 8581-8590 (2013-07-23)
DNA lesions produced by aromatic isocyanates have an extra bulky group on the nucleotide bases, with the capability of forming stacking interaction within a DNA helix. In this work, we investigated the conformation of the 2'-deoxyadenosine and 2'-deoxycytidine derivatives tethering
Tara L Fernandez et al.
Photochemistry and photobiology, 90(6), 1332-1339 (2014-07-22)
Exposure to ultraviolet radiation is closely linked to the development of skin cancers in humans. The ultraviolet B (UVB) radiation wavelength (280-320 nm), in particular, causes DNA damage in epidermal keratinocytes, which are linked to the generation of signature premalignant mutations.
Tu Liang et al.
Journal of chromatography. A, 1388, 110-118 (2015-03-03)
A diterpene glycoside compound, rebaudioside A (commonly abbreviated as RA), was immobilized onto porous silica surface through "thiol-ene" click chemistry strategy. The successful immobilization of the RA on the silica support was confirmed by FT-IR and elemental analysis. Chromatographic characteristics
Fang Wang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(9), 1378-1385 (2013-08-16)
Eighteen compounds were isolated by a combination of various chromatographic techniques including column chromatography over macroporous resin, MCI gel, silica gel, and sephadex LH-20 and reversed-phase HPLC. Their structures were elucidated by spectroscopic data analysis as adinoside A (1), stryspinoside
Georgette Moyle-Heyrman et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(50), 20158-20163 (2013-11-28)
Using a recently developed chemical approach, we have generated a genome-wide map of nucleosomes in vivo in Schizosaccharomyces pombe (S. pombe) at base pair resolution. The shorter linker length previously identified in S. pombe is due to a preponderance of
Ganglong Cui et al.
The Journal of chemical physics, 138(4), 044315-044315 (2013-02-08)
Thiothymidine has a potential application as a photosensitizer in cancer photodynamic therapy (PDT). As the chromophore of thiothymidine, 2-thiothymine exhibits ultrahigh quantum yield of intersystem crossing to the lowest triplet state T(1) (ca. 100%), which contrasts with the excited-state behavior
Dandan Li et al.
Colloids and surfaces. B, Biointerfaces, 110, 485-488 (2013-05-23)
Core-satellite assembly, i.e., gold nanoplates (AuNPs) surrounded by gold nanorods (AuNRs), has been obtained by Thymine-Hg(2+)-Thymine (T-Hg(2+)-T) coordination. A novel label-free localized surface plasmon resonance (LSPR) detection of mercury ions can be performed via the core-satellite assembly. The proposed detection
Anja Hartmann et al.
Journal of photochemistry and photobiology. B, Biology, 149, 149-155 (2015-06-13)
Extremophilic green algae and cyanobacteria are the most abundant species in high mountain habitats, where rough climate conditions such as temperature differences, limited water retention and high ultraviolet (UV) radiation are the cause for a restricted biological diversity in favor
Shiyan Xiao et al.
The Journal of chemical physics, 137(19), 195101-195101 (2012-11-28)
Ab initio constrained molecular dynamics and metadynamics were employed to investigate the mechanism of proton transfer in guanine-cytosine (GC) and adenine-thymine (AT) base pairs in the gas phase at room temperature. It is shown that double proton transfer (DPT) in
Toni Pfaffeneder et al.
Nature chemical biology, 10(7), 574-581 (2014-05-20)
Ten eleven translocation (Tet) enzymes oxidize the epigenetically important DNA base 5-methylcytosine (mC) stepwise to 5-hydroxymethylcytosine (hmC), 5-formylcytosine and 5-carboxycytosine. It is currently unknown whether Tet-induced oxidation is limited to cytosine-derived nucleobases or whether other nucleobases are oxidized as well.
Page 1 of 4