CN
Search Within
V900688
Applied Filters:
Keyword:'V900688'
Showing 1-30 of 195 results for "V900688" within Papers
Chang Dong Han et al.
Clinical orthopaedics and related research, 471(7), 2400-2406 (2013-03-19)
Antibiotic-loaded bone cement (ALBC) has been used in serious cases of musculoskeletal tuberculosis, but the type and amount of antibiotic that should be used in ALBC have not been determined. We therefore determined the (1) elution characteristics and (2) antimycobacterial
T Khawcharoenporn et al.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 15(1), 14-23 (2011-02-01)
The tuberculin skin test (TST) is an important tool for the detection of latent tuberculosis (TB) and the identification of health care workers (HCWs) who require chemoprophylaxis. Although TST is inexpensive, easily available and the preferred test in most TB-prevalent
Amina Jindani et al.
The New England journal of medicine, 371(17), 1599-1608 (2014-10-23)
Tuberculosis regimens that are shorter and simpler than the current 6-month daily regimen are needed. We randomly assigned patients with newly diagnosed, smear-positive, drug-sensitive tuberculosis to one of three regimens: a control regimen that included 2 months of ethambutol, isoniazid
Marianna Grinberg et al.
Archives of toxicology, 88(12), 2261-2287 (2014-11-17)
A long-term goal of numerous research projects is to identify biomarkers for in vitro systems predicting toxicity in vivo. Often, transcriptomics data are used to identify candidates for further evaluation. However, a systematic directory summarizing key features of chemically influenced
Shivaan Cooppan et al.
Pharmaceutical development and technology, 18(5), 1066-1077 (2012-05-18)
This study aimed at developing double crosslinked isoniazid (INH)-loaded polymethyl-methacrylate-ethylcellulose (PMMA-EC) polyspheres for rate-controlled enteric drug delivery. A PMMA solution was manipulated with the addition of EC to produce polyspheres by drop-wise extrusion into a primary crosslinking solution of AlCl3
Corinne S Merle et al.
The New England journal of medicine, 371(17), 1588-1598 (2014-10-23)
Shortening the course of treatment for tuberculosis would be a major improvement for case management and disease control. This phase 3 trial assessed the efficacy and safety of a 4-month gatifloxacin-containing regimen for treating rifampin-sensitive pulmonary tuberculosis. We conducted a
C Hochfellner et al.
Journal of applied microbiology, 118(4), 864-872 (2015-01-22)
The interaction of quinolone and indoloquinazoline alkaloids concerning their antimycobacterial activity was studied. The antimycobacterial and modulating activity of evodiamine (1), rutaecarpine (2) and evocarpine (3) was tested on mycobacteria including three multidrug-resistant (MDR) clinical isolates of Mycobacterium tuberculosis. Antagonistic
PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2.
Ellen M McDonagh et al.
Pharmacogenetics and genomics, 24(8), 409-425 (2014-06-04)
Guan Liu et al.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 25, 82-87 (2014-05-27)
A Mycobacterium parascrofulaceum strain was isolated from a pneumonia patient-the first such reported case from China. The bacteriological characteristics of the strain were determined. Species identification was performed by homologue gene sequence comparison, then a series of biochemical tests was
Hidetoshi Igari et al.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 21(8), 559-563 (2015-06-07)
Chronic kidney disease (CKD) is an increased risk for the development of active tuberculosis, but few studies have analyzed the treatment outcome of pulmonary tuberculosis among CKD patients. A retrospective cohort study was conducted at Chiba-East Hospital in Chiba, Japan.
Guilian Li et al.
PloS one, 10(2), e0119013-e0119013 (2015-02-20)
Isoniazid (INH) and rifampicin (RIF) are the two most effective drugs in tuberculosis therapy. Understanding the molecular mechanisms of resistance to these two drugs is essential to quickly diagnose multidrug-resistant (MDR) tuberculosis and extensive drug-resistant tuberculosis. Nine clinical Mycobacterium tuberculosis
Guillermo Alberto Keller et al.
International journal of clinical pharmacology and therapeutics, 52(4), 292-302 (2014-01-23)
Metabolic clearance of isoniazid (INH) may be up to 10 times faster in individuals who are rapid acetylators compared with slow acetylators. In addition, the acetylation phenotype has been suggested to change with age. A better knowledge of the age
Betzaida Cuevas-Córdoba et al.
Antimicrobial agents and chemotherapy, 59(9), 5455-5462 (2015-07-01)
Ethambutol inhibits arabinogalactan and lipoarabinomannan biosynthesis in mycobacteria. The occurrence of mutations in embB codon 306 in ethambutol-susceptible isolates and their absence in resistant isolates has raised questions regarding the utility of this codon as a potential marker for resistance
Gabriela Torrea et al.
The Journal of antimicrobial chemotherapy, 70(8), 2300-2305 (2015-05-16)
The objective of this study was to evaluate the performance of the BACTEC MGIT960 system to test the susceptibility to bedaquiline for Mycobacterium tuberculosis complex. We determined the quality control (QC) range of bedaquiline using the M. tuberculosis H37Rv reference
Fernanda Abilleira et al.
Biomedica : revista del Instituto Nacional de Salud, 35(2), 285-291 (2015-11-05)
Reports of Mycobacterium tuberculosis resistant to multiple drugs are increasing globally and laboratories are becoming increasingly aware of the need for drug susceptibility testing. In recent years, due to the long time required by conventional drug susceptibility testing, new approaches
N Guo et al.
Letters in applied microbiology, 58(4), 344-349 (2013-12-18)
Previous studies have shown that isoimperatorin (IO), a furanocoumarin isolated from several medicinal plants, has antimycobacterial activity against Mycobacterium tuberculosis strain H37Rv (ATCC 27294). This study demonstrated that IO has antimycobacterial activity against 2 drug-sensitive and 6 drug-resistant isolates, with
Seo Yun Kim et al.
Yonsei medical journal, 54(5), 1227-1233 (2013-08-07)
The aim of this study was to elucidate the effects of immunocompromising comorbidities on treatment response and adverse reactions in older tuberculosis (TB) patients. The medical records of 182 patients older than 65 years with proven TB by positive culture
Alice L den Hertog et al.
PloS one, 8(2), e57997-e57997 (2013-03-08)
Recently we proposed exploring the potential of treatment stimulated testing as diagnostic method for tuberculosis (TB). An infection controlled placebo controlled mouse study was performed to investigate whether serum cytokine levels changed measurably during the early phase of TB chemotherapy.
[Primary sinonasal tuberculosis: apropos of a case].
Rachid Bouchentouf et al.
The Pan African medical journal, 14, 29-29 (2013-03-19)
Anthony Vocat et al.
Antimicrobial agents and chemotherapy, 59(7), 4012-4019 (2015-04-22)
Targeting dormant Mycobacterium tuberculosis represents a challenge to antituberculosis drug discovery programs. We previously reported and validated the use of the streptomycin (STR)-dependent M. tuberculosis 18b strain as a tool for assessing drug potency against nonreplicating bacteria both in vitro
Betina Durovni et al.
The Lancet. Infectious diseases, 13(10), 852-858 (2013-08-21)
Preventive therapy for tuberculosis in patients with HIV is effective, but it has not been widely implemented in moderate or high-burden settings. We assessed the effect of widespread use of isoniazid preventive therapy on rates of tuberculosis and death in
Courtney M Yuen et al.
The Pediatric infectious disease journal, 32(5), e217-e226 (2013-01-26)
Isoniazid resistance is an obstacle to the treatment of tuberculosis disease and latent tuberculosis infection in children. We aim to summarize the literature describing the risk of isoniazid-resistant tuberculosis among children with tuberculosis disease. We did a systematic review of
Verónica Ramírez-Alcántara et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(11), G1002-G1010 (2014-04-20)
Pharmacotherapy based on 5-aminosalicylic acid (5-ASA) is a preferred treatment for ulcerative colitis, but variable patient response to this therapy is observed. Inflammation can affect therapeutic outcomes by regulating the expression and activity of drug-metabolizing enzymes; its effect on 5-ASA
A trial of mass isoniazid preventive therapy for tuberculosis control.
Kingsley N Ukwaja et al.
The New England journal of medicine, 370(17), 1661-1661 (2014-04-25)
A fresh look at the mechanism of isoniazid-induced hepatotoxicity.
I G Metushi et al.
Clinical pharmacology and therapeutics, 89(6), 911-914 (2011-03-18)
Sahal Al-Hajoj et al.
PloS one, 9(11), e113472-e113472 (2014-11-20)
Bacillus Calmette Guerin (BCG) is the only available vaccine for tuberculosis (TB). Low grade complications in healthy recipients and disseminated vaccine associated complications among immuno-suppressed individuals were noticed globally after administration. Recently a series of clinically suspected BCG associated suppurative
Jotam G Pasipanodya et al.
The Journal of infectious diseases, 208(9), 1464-1473 (2013-08-01)
Based on a hollow-fiber system model of tuberculosis, we hypothesize that microbiologic failure and acquired drug resistance are primarily driven by low drug concentrations that result from pharmacokinetic variability. Clinical and pharmacokinetic data were prospectively collected from 142 tuberculosis patients
Jonathan L Zelner et al.
American journal of respiratory and critical care medicine, 189(7), 853-859 (2014-03-07)
Individuals living with patients with tuberculosis (TB) are at elevated risk of infection and disease, with children at greatest risk. The World Health Organization recommends isoniazid preventive therapy (IPT) for HIV-positive contacts and those younger than 5 years. Despite these
Peng Liu et al.
Biomedical chromatography : BMC, 27(9), 1150-1156 (2013-05-01)
Medications compounded with isoniazid (INH) are usually applied to surgical sites at the completion of surgery to locally kill postoperative residual tubercle bacilli. However, the distribution and elimination of INH in the vertebrae in vivo are not known. In this
B K Viswanath et al.
Indian journal of leprosy, 84(3), 227-232 (2013-03-15)
Severe Cutaneous Adverse Reaction (SCAR) represents the spectrum of adverse drug reactions from erythema multiforme, Stevens - Johnson syndrome (SJS) to Toxic Epidermal Necrolysis (TEN). A 55 year old lady presented in a toxic state with peeling of skin, blisters
Page 1 of 7