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Showing 1-30 of 1693 results for "W292907" within Papers
Iain M McIntyre et al.
Journal of analytical toxicology, 39(2), 152-155 (2014-12-18)
A 24-year-old man whose medical history was significant for alcohol abuse and depression was found unresponsive in bed. He had several prior suicide attempts with 'pills' and had also been hospitalized for an accidental overdose on a previous occasion. Autopsy
Takuya Kitamura et al.
The Biochemical journal, 465(1), 79-87 (2014-10-07)
Aldehyde dehydrogenases (ALDHs) catalyse the conversion of toxic aldehydes into non-toxic carboxylic acids. Of the 21 ALDHs in mice, it is the ALDH3 family members (ALDH3A1, ALDH3A2, ALDH3B1, ALDH3B2 and ALDH3B3) that are responsible for the removal of lipid-derived aldehydes.
Maria Gagliardi et al.
Journal of cell science, 127(Pt 22), 4918-4926 (2014-09-23)
A key step in the canonical Wnt signalling pathway is the inhibition of GSK3β, which results in the accumulation of nuclear β-catenin (also known as CTNNB1), and hence regulation of target genes. Evidence suggests that endocytosis is required for signalling
Patricia M Davidson et al.
Integrative biology : quantitative biosciences from nano to macro, 7(12), 1534-1546 (2015-11-10)
The ability of cells to migrate through tissues and interstitial spaces is an essential factor during development and tissue homeostasis, immune cell mobility, and in various human diseases. Deformation of the nucleus and its associated lamina during 3-D migration is
Sergio Armenta et al.
Journal of chromatography. A, 1384, 1-8 (2015-02-11)
We developed and evaluated two different strategies for determining abuse drugs based on (i) the analysis of saliva by ion mobility spectrometry (IMS) after thermal desorption and (ii) the joint use of IMS and infrared (IR) spectroscopy after liquid-liquid microextraction
Eva Cífková et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1000, 14-21 (2015-07-25)
The characterization of differences among polar lipid classes in tumors and surrounding normal tissues of 20 kidney cancer patients is performed by hydrophilic interaction liquid chromatography (HILIC) coupled to electrospray ionization mass spectrometry (ESI-MS). The detailed analysis of identified lipid
Robert Reichert et al.
ChemSusChem, 8(21), 3677-3687 (2015-09-19)
To better understand organic-molecule-assisted photo-electrochemical water splitting, photo-electrochemistry and on-line mass spectrometry measurements are used to investigate the photo-electrochemical oxidation of the C1 molecules methanol, formaldehyde, and formic acid over WO3 film anodes in aqueous solution and its competition with
Kyle D Dukes et al.
Analytical biochemistry, 458, 43-48 (2014-04-24)
Silver nanoparticles have been modified with self-assembled monolayers of hydroxyl-terminated long chain thiols and encapsulated with a silica shell. The resulting core-shell nanoparticles were used as optical labels for cell analysis using flow cytometry and microscopy. The excitation of plasmon
Elisaveta N Voynova et al.
Journal of immunology (Baltimore, Md. : 1950), 194(4), 1503-1513 (2015-01-18)
Chronic inflammatory conditions, such as in autoimmune disease, can disturb immune cell homeostasis and induce the expansion of normally rare cell populations. In our analysis of various murine models of lupus, we detect increased frequency of an uncommon subset identified
Iain M McIntyre et al.
Journal of analytical toxicology, 39(2), 156-159 (2014-11-29)
A 20-year-old man, a college student, became unresponsive in front of his girlfriend. He was known to consume alcohol and take an unknown drug at some point while in attendance at a local music festival earlier in the day/evening. Upon
Capillary electrophoresis-mass spectrometry as a new approach to analyze neonicotinoid insecticides.
Laura Sánchez-Hernández et al.
Journal of chromatography. A, 1359, 317-324 (2014-08-03)
This paper represents the first report of a capillary electrophoresis (CE) method compatible with mass spectrometry (MS) detection for simultaneously analyzing seven neonicotinoid insecticides (acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid and thiamethoxam). Different variables affecting CE separation (buffer concentration, pH
Jia-Le Song et al.
Iranian journal of pharmaceutical research : IJPR, 13(4), 1369-1378 (2015-01-15)
The present study was designed to investigate the protective effect of ethanol extracts from Lindera coreana leaves (LCE) on UVB-induced oxidative stress in HaCaT keratinocytes. The HaCaT cells were pretreated with LCE for 24 h and then exposed to UVB
Mahdi Shahmiri et al.
Scientific reports, 5, 16378-16378 (2015-11-18)
Aurein 1.2 is a 13 residue antimicrobial peptide secreted by the Australian tree frog Litoria Aurea. It is a surface-acting membrane disrupting peptide that permeabilizes bacterial membranes via the carpet mechanism; the molecular details of this process are mostly unknown.
Coilín Boland et al.
Cellular and molecular life sciences : CMLS, 71(24), 4895-4910 (2014-07-12)
Membrane proteins are key elements in cell physiology and drug targeting, but getting a high-resolution structure by crystallographic means is still enormously challenging. Novel strategies are in big demand to facilitate the structure determination process that will ultimately hasten the
Jeanette N McClintick et al.
Pharmacology, biochemistry, and behavior, 129, 87-96 (2014-12-30)
Alcohol binge-drinking during adolescence is a serious public health concern with long-term consequences. We used RNA sequencing to assess the effects of excessive adolescent ethanol binge-drinking on gene expression in the dorsal raphe nucleus (DRN) of alcohol preferring (P) rats.
Jiheng Li et al.
International journal of biological macromolecules, 72, 1097-1103 (2014-12-03)
The molecular aggregation of collagen solution (Col) in the presence of glycerol (Col-G) and 2-propanol (Col-P) was investigated. The transition temperature (Tm) of collagen, determined by ultra-sensitive differential scanning calorimetry, increased proportionally to the concentration of glycerol about 0.929 °C
Tobias Glaser et al.
The journal of physical chemistry letters, 6(15), 2913-2918 (2015-08-13)
The organic cation and its interplay with the inorganic lattice underlie the exceptional optoelectronic properties of organo-metallic halide perovskites. Herein we report high-quality infrared spectroscopic measurements of methylammonium lead halide perovskite (CH3NH3Pb(I/Br/Cl)3) films and single crystals at room temperature, from
Jessica Aceto et al.
PloS one, 10(6), e0126928-e0126928 (2015-06-11)
Teleost fish such as zebrafish (Danio rerio) are increasingly used for physiological, genetic and developmental studies. Our understanding of the physiological consequences of altered gravity in an entire organism is still incomplete. We used altered gravity and drug treatment experiments
Punitha Vasanthan et al.
Journal of cellular and molecular medicine, 19(3), 566-580 (2014-12-06)
MicroRNAs (miRNAs) are small non-coding RNAs that regulate translation of mRNA into protein and play a crucial role for almost all biological activities. However, the identification of miRNAs from mesenchymal stem cells (MSCs), especially from dental pulp, is poorly understood.
Xinguang Zhou et al.
Journal of chromatography. A, 1409, 125-131 (2015-07-25)
Concentration of blood catecholamines (CAs) is linked to a host of cardiovascular diseases, including hypertension and stenocardia. The matrix interferences and low concentration require tedious sample pretreatment methods before quantitative analysis by the gold standard method of high-performance liquid chromatography-electrochemical
Joshua C Doloff et al.
BMC cancer, 15, 375-375 (2015-05-09)
Cyclophosphamide treatment on a six-day repeating metronomic schedule induces a dramatic, innate immune cell-dependent regression of implanted gliomas. However, little is known about the underlying mechanisms whereby metronomic cyclophosphamide induces innate immune cell mobilization and recruitment, or about the role
Bo'an Zheng et al.
TheScientificWorldJournal, 2014, 703804-703804 (2014-09-13)
Due to changes in lifestyle, particularly changes in dietary habits, colorectal cancer (CRC) increased in recent years despite advances in treatment. Nearly one million new cases diagnosed worldwide and half a million deaths make CRC a leading cause of cancer
Ying Liu et al.
Biochimica et biophysica acta, 1848(1 Pt A), 67-75 (2014-10-07)
Molecular interactions between engineered nanomaterials (ENM) and biomembranes are not well understood. This study investigated the effects of particle size and surface functional group on polystyrene nanoparticles' (PNPs) potency for biomembrane disruption. Electrochemical impedance spectroscopy was used to measure changes
B Houston et al.
Reproduction (Cambridge, England), 149(6), 587-596 (2015-03-15)
Reactive oxygen species (ROS) are known to play an important role in the regulation of human sperm function. In this study, we demonstrate for the first time that human spermatozoa possess interleukin-induced gene 1 (IL4I1), an l-amino acid oxidase (LAAO)
Kar Wey Yong et al.
Scientific reports, 5, 9596-9596 (2015-04-16)
Cryopreservation represents an effective technique to maintain the functional properties of human adipose-derived stem cells (ASCs) and allows pooling of cells via long-term storage for clinical applications, e.g., cell-based therapies. It is crucial to reduce freezing injury during the cryopreservation
Huiling Wu et al.
International journal of molecular sciences, 15(11), 20555-20571 (2014-11-13)
In our previous study, we identified an association of high expression of c3orf1, also known as TIMMDC1 (translocase of inner mitochondrial membrane domain-containing protein 1), with metastatic characteristics in lung carcinoma cells. To investigate the preliminary function and mechanism of
D Mata et al.
Nanoscale, 7(20), 9238-9251 (2015-05-01)
The risk-benefit balance for carbon nanotubes (CNTs) dictates their clinical fate. To take a step forward at this crossroad it is compulsory to modulate the CNT in vivo biocompatibility and biodegradability via e.g. chemical functionalization. CNT membranes were functionalised combining
Xiaoyu Xie et al.
Journal of chromatography. A, 1405, 32-39 (2015-06-17)
Magnetic molecularly imprinted polymers (MMIPs) have become a hotspot owing to the dual functions of target recognition and magnetic separation. In this study, the MMIPs were obtained by the surface-initiated reversible addition fragmentation chain transfer (RAFT) polymerization using Sudan I
Arun M Unni et al.
eLife, 4, e06907-e06907 (2015-06-06)
Human lung adenocarcinomas (LUAD) contain mutations in EGFR in ∼15% of cases and in KRAS in ∼30%, yet no individual adenocarcinoma appears to carry activating mutations in both genes, a finding we have confirmed by re-analysis of data from over
Radhika Dhakal et al.
PloS one, 10(2), e0117712-e0117712 (2015-02-14)
Specific wavelengths of light can exert various physiological changes in plants, including effects on responses to disease incidence. To determine whether specific light wavelength had effects on rotting disease caused by Pseudomonas putida 229, soybean sprouts were germinated under a
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