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Showing 1-30 of 96 results for "Y0000054" within Papers
Xiao-Gang Wang et al.
The Journal of organic chemistry, 78(18), 9488-9493 (2013-08-21)
We report herein for the first time the enantioselective synthesis of 8-aza-PGE1. The synthesis used the cross olefin metathesis reaction to connect the 5-vinyl-γ-lactam subunit, prepared from (R)-malic acid via the Ley's sulfone-based α-amidalkylation protocol (dr = 6.8:1), with the
W Blogowski et al.
Journal of biological regulators and homeostatic agents, 26(3), 429-438 (2012-10-05)
Postoperative decline of renal function remains a common and unpredictable complication after abdominal aortic aneurysm (AAA) reconstruction. The oxidative stress that occurs during perioperative ischemia/reperfusion injury (I/R) may contribute to the development of this complication. In this study, the influence
Mikkel Fode et al.
BJU international, 112(7), 998-1008 (2013-07-06)
The pathophysiology of erectile dysfunction after radical prostatectomy (RP) is believed to include neuropraxia, which leads to temporarily reduced oxygenation and subsequent structural changes in penile tissue. This results in veno-occlusive dysfunction, therefore, penile rehabilitation programmes focus on tissue oxygenation.
A Creutzig et al.
VASA. Zeitschrift fur Gefasskrankheiten, 33(3), 137-144 (2004-10-06)
The relevance of Prostaglandin El (PGE,) in the treatment of peripheral arterial occlusive disease stage III and IV was to be evaluated for the first time by a meta-analysis. Altogether, 643 patients were analyzed from seven randomized, controlled PGE1 studies
Marc Dufour et al.
Biochemical and biophysical research communications, 451(4), 587-591 (2014-08-17)
The inflammatory prostaglandin E2 (PGE2) cytokine plays a key role in the development of colon cancer. Several studies have shown that PGE2 directly induces the growth of colon cancer cells and furthermore promotes tumor angiogenesis by increasing the production of
Yasuyuki Hara et al.
The Journal of surgical research, 184(2), 1134-1142 (2013-05-22)
To resolve the shortage of donors associated with liver transplantation, the potential uncontrolled non-heart-beating donor (UNHBD) pool is expected to increase. However, warm ischemia-reperfusion injury leads to inferior survival in transplantation using the grafts from UNHBD compared with those from
Yasuyuki Takai et al.
Investigative ophthalmology & visual science, 54(4), 3065-3071 (2013-04-13)
To report the efficacy of systemic prostaglandin E1 (PGE1) monotherapy for treating acute central retinal artery occlusion (CRAO). The best-corrected visual acuity (BCVA) and side effects were evaluated retrospectively in 10 consecutive eyes (nine patients; mean age, 61.3 years) with
[Intracavernous injection test by prostaglandin E1].
Toshikazu Otani
Nihon rinsho. Japanese journal of clinical medicine, 60 Suppl 6, 173-177 (2002-08-09)
Ivan D Tarandovskiy et al.
PloS one, 8(2), e55688-e55688 (2013-02-14)
Thrombin generation assay is a convenient and widely used method for analysis of the blood coagulation system status. Thrombin generation curve (TGC) is usually bell-shaped with a single peak, but there are exceptions. In particular, TGC in platelet-rich plasma (PRP)
Alexander C Ford et al.
The American journal of gastroenterology, 108(10), 1566-1574 (2013-06-12)
There has been no definitive synthesis of the evidence for any benefit of available pharmacological therapies in opioid-induced constipation (OIC). We conducted a systematic review and meta-analysis to address this deficit. We searched MEDLINE, EMBASE, EMBASE Classic, and the Cochrane
Beatriz Gras-Miralles et al.
Clinical interventions in aging, 8, 191-200 (2013-02-27)
Chronic constipation is a common disorder in the general population, with higher prevalence in the elderly, and is associated with worse quality of life and with greater health care utilization. Lubiprostone is an intestinal type-2 chloride channel activator that increases
Renata N Gomes et al.
Lipids in health and disease, 11, 171-171 (2012-12-13)
In many types of cancer, prostaglandin E2 (PGE2) is associated with tumour related processes including proliferation, migration, angiogenesis and apoptosis. However in gliomas the role of this prostanoid is poorly understood. Here, we report on the proliferative, migratory, and apoptotic
Heidi A Trau et al.
Biology of reproduction, 92(1), 15-15 (2014-11-08)
Rapid angiogenesis occurs as the ovulatory follicle is transformed into the corpus luteum. To determine if luteinizing hormone (LH)-stimulated prostaglandin E2 (PGE2) regulates angiogenesis in the ovulatory follicle, cynomolgus macaques received gonadotropins to stimulate multiple follicular development and chorionic gonadotropin
J G Ray
Transplantation, 66(4), 476-483 (1998-09-12)
To assess whether prostaglandin E1 analogs have a role in either reducing renal allograft rejection or improving renal function among both transplant and nontransplant patients. Studies were identified through Ovid MEDLINE between 1981 and December 1997 using multiple MeSH headings
Michael Berner et al.
The journal of sexual medicine, 9(12), 3089-3107 (2012-10-24)
As yet, a summary of research evidence concerning the efficacy of psychological treatment in male sexual dysfunction is lacking. Our systematic review gives an overview of the efficacy of psychosocial interventions in all male sexual dysfunctions. Main outcome measures included
[Efficacy and perspectives of use of vasaprostan (prostaglandin E1) in rheumatology].
N G Gusev
Terapevticheskii arkhiv, 74(5), 85-88 (2002-06-29)
Robert C De Lisle
BMC gastroenterology, 12, 156-156 (2012-11-08)
Lubiprostone is a synthetic bicyclic fatty acid derivative of prostaglandin E1 (PGE1) used for chronic constipation. The best known action of lubiprostone is simulation of Cl- dependent fluid secretion. In a mouse model of the genetic disease cystic fibrosis, we
Raymond A Costabile et al.
Expert opinion on pharmacotherapy, 9(8), 1421-1429 (2008-05-14)
Erectile dysfunction is a disease affecting millions of men over the age of 40. Alprostadil, a synthetic form of prostaglandin E(1), was introduced almost three decades ago, and is today considered an alternative treatment for erectile dysfunction. The purpose of
Prostaglandin E1 use during neonatal transfer: potential beneficial role in persistent pulmonary hypertension of the newborn.
Neelam Gupta et al.
Archives of disease in childhood. Fetal and neonatal edition, 98(2), F186-F188 (2012-12-14)
O Gottschalk et al.
Scandinavian journal of rheumatology, 43(5), 356-363 (2014-05-16)
The use of statins in the prevention and treatment of cardiovascular diseases is well established. Their use as anti-inflammatory and immunomodulatory agents in the treatment of rheumatoid arthritis (RA) has also been investigated, with several clinical and experimental studies indicating
Alprostadil in impotence.
M J Artoux et al.
DICP : the annals of pharmacotherapy, 25(4), 363-366 (1991-04-01)
Marcello Gomide et al.
The Journal of thoracic and cardiovascular surgery, 146(5), 1146-1151 (2013-10-17)
Preoperative comorbidities (PCMs) are known risk factors for Norwood stage I (NW1). We tested the hypothesis that short-term bilateral pulmonary arterial banding (bPAB) before NW1 could improve the prognosis of these high-risk patients. From January 2006 to October 2011, 17
Th Weiss
VASA. Zeitschrift fur Gefasskrankheiten, 32(4), 187-192 (2003-12-26)
Mode of action of prostaglandin E1 in the treatment of peripheral arterial disease. Prostaglandin E1 has been used for the first time in the treatment of peripheral arterial occlusive disease 30 years ago. Although widely used, the exact mechanism of
Masayuki Hashiguchi et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 124(6), 321-332 (2004-06-01)
To study the effectiveness for the treatment of intermittent claudication (IC) of three drugs with antiplatelet effects, cilostazol, beraprost sodium, and prostaglandin E(1) (PGE(1)), by using a systemic review of literature and a meta-analysis. A search was undertaken for studies
Pierre Costa et al.
Drugs, 72(17), 2243-2254 (2012-11-23)
The global burden of erectile dysfunction (ED) is increasing. It is estimated that 8-19% of men in Europe have ED and that by 2025 the prevalence of ED worldwide will reach 322 million. The gold standard therapy for ED is
R Urciuoli et al.
The Cochrane database of systematic reviews, (2)(2), CD001784-CD001784 (2004-04-24)
Erectile dysfunction (ED), the inability to achieve or maintain an erection sufficient for satisfactory sexual activity, is one of the most common sexual dysfunctions in men. ED may have a dramatic impact on the quality of life of many men
Claire M Ervin et al.
Reviews on recent clinical trials, 8(1), 9-22 (2012-11-08)
Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders and it is characterized by episodes of abdominal pain and altered bowel functions. The specific bowel disturbances of diarrhea, constipation or an alternation between the two defines the
Jun Takahashi et al.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 18(2), 208-215 (2012-12-04)
Quality of life (QOL) is a concern for patients with lumbar spinal stenosis (LSS). In this study, QOL was examined using the 5-item EuroQol (EQ-5D). QOL and activities of daily living (ADL) were surveyed for 91 patients who visited 18
Kelly A Brant et al.
American journal of respiratory cell and molecular biology, 49(1), 105-113 (2013-03-26)
Numerous epidemiological studies have linked exposure to particulate matter (PM) air pollution with acute respiratory infection and chronic respiratory and cardiovascular diseases. We have previously shown that soluble nickel (Ni), a common component of PM, alters the release of CXC
Li-Ping Kang et al.
Phytochemistry, 107, 182-189 (2014-08-31)
Sixteen steroidal saponins, including seven previously unreported compounds, were isolated from Tribulus terrestris. The structures of the saponins were established using 1D and 2D NMR spectroscopy, mass spectrometry, and chemical methods. They were identified as: 26-O-β-d-glucopyranosyl-(25R)-furost-4-en-2α,3β,22α,26-tetrol-12-one (terrestrinin C), 26-O-β-d-glucopyranosyl-(25R)-furost-4-en-22α,26-diol-3,12-dione (terrestrinin
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