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Molecular cloning of cDNA for murine interleukin-3.

Nature (1984-01-19)
M C Fung, A J Hapel, S Ymer, D R Cohen, R M Johnson, H D Campbell, I G Young
PMID6420702
ABSTRACT

The cDNA sequence for murine interleukin-3, one of the colony stimulating factors that regulate haematopoiesis, codes for a polypeptide of 166 amino acids including a putative signal peptide. The predicted amino acid sequence indicates that formation of mature interleukin-3 involves proteolytic removal of not only the signal peptide but additional amino-terminal amino acids.