- Expeditious synthesis of phenanthrenes via CuBr2-catalyzed coupling of terminal alkynes and N-tosylhydrazones derived from o-formyl biphenyls.
Expeditious synthesis of phenanthrenes via CuBr2-catalyzed coupling of terminal alkynes and N-tosylhydrazones derived from o-formyl biphenyls.
Organic letters (2011-08-31)
Fei Ye, Yi Shi, Lei Zhou, Qing Xiao, Yan Zhang, Jianbo Wang
PMID21875127
ABSTRACT
A new method for the synthesis of phenanthrenes via ligand-free CuBr(2)-catalyzed coupling/cyclization of terminal alkynes with N-tosylhydrazones derived from o-formyl biphenyls has been developed. This new synthesis has wide range of functional group compatibility.