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  • Evaluation of Plastic-Compressed Collagen for Conjunctival Repair in a Rabbit Model.

Evaluation of Plastic-Compressed Collagen for Conjunctival Repair in a Rabbit Model.

Tissue engineering. Part A (2018-12-07)
Joana Witt, Maria Borrelli, Sonja Mertsch, Gerd Geerling, Kristina Spaniol, Stefan Schrader
ABSTRACT

Conjunctival integrity is crucial for a healthy ocular surface and visual acuity. In severe cases of inflammatory surface disorders or after trauma, thermal or chemical burns as well as after ocular surgery, a surgical reconstruction using conjunctival substitutes is required. Due to limitations of currently used substitutes, such as the amniotic membrane, there is a need for the development of new scaffolds of consistent quality for conjunctival reconstruction. This study explored the biocompatibility and surgical usability of plastic-compressed collagen as an alternative conjunctival substitute in a rabbit model.