- Two new triterpenoids with antimicrobial activity from the leaves and twigs of Orophea yunnanensis.
Two new triterpenoids with antimicrobial activity from the leaves and twigs of Orophea yunnanensis.
Natural product research (2018-06-09)
Wei Zhao, Xiao-Wei Gong, Yuan-Xing Duan, Ji Yang, Xia Wu, Xian-Jun Jiang, Xiao-Hua Xu, Yong-Kuan Chen, Liu Yang, Fei Wang, Xiao-Long Yang
PMID29882434
ABSTRACT
Two new triterpenoids, 3-O-(4',5'-dihydroxybenzoyl)-lup-20(29)-en (1) and 3-O-(6'-desmethysyringyl)-13α-methyl-27-norolean-14-en-3β-ol (2), were isolated from the leaves and twigs of Orophea yunnanensis. Their structures were identified by extensive spectroscopic experiments (NMR and MS) and comparison with literature data. Compounds 1 and 2 exhibited the moderate inhibitory activity against Sclerotinia sclerotiorum, Ceratocystis fimbriata and Verticillium dahliae Kleb with MIC values from 50 to 25 μg/mL, and also displayed the weak activity selectively against tested bacteria strains with MIC values from 100 to 50 μg/mL.
MATERIALS