- Facile Synthesis of a Series of Non-Symmetric Thioethers Including a Benzothiazole Moiety and Their Use as Efficient In Vitro anti-Trypanosoma cruzi Agents.
Facile Synthesis of a Series of Non-Symmetric Thioethers Including a Benzothiazole Moiety and Their Use as Efficient In Vitro anti-Trypanosoma cruzi Agents.
Molecules (Basel, Switzerland) (2019-08-28)
Alcives Avila-Sorrosa, Jazz D Tapia-Alvarado, Benjamín Nogueda-Torres, Karla Fabiola Chacón-Vargas, Francisco Díaz-Cedillo, María Elena Vargas-Díaz, David Morales-Morales
PMID31450583
ABSTRACT
A series of 2-benzylsulfanyl benzothiazole (BTA) derivatives were synthesized and fully characterized and in vitro tested against two strains of T. cruzi (NINOA and INC-5), exhibiting good activities at low concentrations.
MATERIALS