- Visible light promoted coupling of alkynyl bromides and Hantzsch esters for the synthesis of internal alkynes.
Visible light promoted coupling of alkynyl bromides and Hantzsch esters for the synthesis of internal alkynes.
Organic & biomolecular chemistry (2018-12-12)
Zhi-Yong Song, Chun-Lin Zhang, Song Ye
PMID30534692
ABSTRACT
A metal-free visible light promoted C(sp3)-C(sp) coupling reaction of alkynyl bromides and Hantzsch esters was developed, giving internal alkynes with primary, secondary, tertiary alkyl or other functional groups in good to high yields.