Asymmetric total synthesis of antiochic acid.

Asymmetric total synthesis of antiochic acid.

Organic letters (2008-04-29)

Yu-Jun Zhao, Teck-Peng Loh

ABSTRACT

The first asymmetric total synthesis of antiochic acid using bioinspired polyene cyclization strategy is described. Both good yield and good asymmetric induction were obtained.

MATERIALS

Product Number

Brand

Product Description

663212

Sigma-Aldrich

Isopropenylboronic acid pinacol ester, contains BHT as stabilizer, 94.5%