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K-252a, a potent inhibitor of protein kinase C from microbial origin.

The Journal of antibiotics (1986-08-01)
H Kase, K Iwahashi, Y Matsuda
ABSTRACT

K-252a, a metabolite isolated from the culture broth of Nocardiopsis sp. K-252a, was found to exhibit an extremely potent inhibitory activity on protein kinase C. The IC50 value was 32.9 nM.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
K-252a, Ready Made Solution, from Nonomuraea longicatena, >98%