Clear cell renal cell carcinoma.

Clear cell renal cell carcinoma.

Clinics in laboratory medicine (2005-04-26)

David J Grignon, Mingxin Che

ABSTRACT

Clear cell RCC is the most common type of RCC that occurs in adults. It has the worst prognosis among the common epithelial tumors of the kidney. Histologically, a wide range of morphologic patterns can be encountered. Those cases with a multi-locular cystic architecture are considered to be a distinct subtype because of the clinicopathologic features.

MATERIALS

Product Number

Brand

Product Description

412512

Sigma-Aldrich

IRE1 Inhibitor III, 4μ8C, IRE1 Inhibitor III, CAS 14003-96-4, is a cell-permeable. Covalent inhibitor of IRE1 RNase activity (IC₅₀ = 550 and 45 nM, respectively, with 0 & 16 min preincubation in RNA cleavage assays).

475991

Sigma-Aldrich

mTOR Inhibitor XI, Torin1, mTOR Inhibitor XI, Torin1, CAS 1222998-36-8, is a cell-permeable, highly potent, ATP-competitive inhibitor of mTOR and DNA-PK (IC50 = 4.32 and 6.34 nM, respectively).

239763

Sigma-Aldrich

1-Decanol, ≥98%

MABE343

Sigma-Aldrich

Anti-Puromycin Antibody, clone 12D10, clone 12D10, from mouse

557368

Sigma-Aldrich

Rotenone, A mitochondrial toxin and a potent, reversible, and competitive inhibitor of complex I (NADH-CoQ reductase) of the respiratory chain.

05892791001

Roche

cOmplete^™ ULTRA Tablets, Mini, EDTA-free, EASYpack Protease Inhibitor Cocktail, Tablets supplied in foil blister packs.