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  • The high mobility group I-C gene (HMGI-C): polymorphism and genetic localization.

The high mobility group I-C gene (HMGI-C): polymorphism and genetic localization.

Human genetics (1997-01-01)
C S Ishwad, M D Shriver, D M Lassige, R E Ferrell
ABSTRACT

We have identified a highly informative dinucleotide repeat in the 5'-flanking region of the human high mobility group I-C (HMGI-C) gene. This polymorphism consists of 18-37 copies of a (CT) repeat with an observed heterozygosity of 82-83% in African Americans and Caucasians. Linkage analysis in CEPH pedigrees localized the HMGI-C gene to chromosome region 12q13-15 with no recombination observed between HMCI-C and markers D12S102 and D12S8.