- A one-pot entry to a novel 3-H-benzo[d]pyrazolo[1,5-b]isothiazole ring system.
A one-pot entry to a novel 3-H-benzo[d]pyrazolo[1,5-b]isothiazole ring system.
Molecular diversity (2006-03-11)
Paola Vicini, Matteo Incerti, Rocco Ferretti, Franca Zanardi
PMID16528601
ABSTRACT
The phosphorus ylide obtained from the reaction between 2-aminobenzo[d]isothiazol-3-one and dimethyl acetylenedicarboxylate in the presence of triphenylphosphine undergoes a smooth intramolecular Wittig-type reaction to produce, in a one-pot reaction, 3-H-benzo[d]pyrazolo[1,5-b]isothiazole-2,3a-dicarboxylic acid dimethyl ester, a novel functionalized heterocyclic compound.
MATERIALS