Nornicotine-organocatalyzed aqueous reduction of alpha,beta-unsaturated aldehydes.

Nornicotine-organocatalyzed aqueous reduction of alpha,beta-unsaturated aldehydes.

Chemical communications (Cambridge, England) (2008-03-26)

Andrew P Brogan, Tobin J Dickerson, Kim D Janda

ABSTRACT

Nornicotine, a native component of tobacco and minor nicotine metabolite, was found to catalyze the chemoselective reduction of alpha,beta-unsaturated aldehydes under homogeneous aqueous conditions.

MATERIALS

Product Number

Brand

Product Description

N3018

Sigma-Aldrich

(±)-Nornicotine, ≥98% (TLC), liquid

N-071

Supelco

(±)-Nornicotine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®