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The MPEG monophosphate ester: synthesis and characterization.

Journal of biomaterials science. Polymer edition (2009-10-31)
Stanislaw Penczek, Krzysztof Kaluzynski, Blazej Wisniewski, Julia Pretula, Ryszard Szymanski, Grzegorz Lapienis
ABSTRACT

Methods of preparation of the phosphoric ester of monomethyl ether of poly(ethylene glycol) (MPEG-P) from MPEG (M(n) = 550 and 2000) and phosphoric acid (P), or its derivatives - pyrophosphoric acid (PY), polyphosphoric acid (PP) and POCl(3)- are described and compared. MPEG-P was isolated in a pure state (no detectable impurities) and characterized.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Polyphosphoric acid, ~105% H3PO4 basis
Sigma-Aldrich
Polyphosphoric acid, reagent grade, 115% H3PO4 basis