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[Spectrophotometric and HPLC evaluation of ceftazidime stability].

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi (2010-06-01)
B Palade, B Cioroiu, Doina Lazăr, Andreia Corciovă, M I Lazăr
PMID20509313
ABSTRACT

In this paper we followed up the stability of ceftazidime, raw material used in drug industry. Matherials and methods: We used three spectrophotometric methods based on ceftazidime property to form complexes with p-chloranilic acid (ac. p-CA), 3-methylbenzothiazolin-2-on hydrazone (MBTH) and N-(1-naphtil) etilendiamine (NEDA) and a chromatographic method (HPLC). Our results revealed that the substances analyzed maintained minimum content allowable.