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Merck
CN

Statins: in the beginning.

The journal of the Royal College of Physicians of Edinburgh (2010-06-01)
K S Lyons, M Harbinson
ABSTRACT

Since the first human trial of a hydroxymethylglutaryl-coenzyme A (HMG CoA) reductase inhibitor in 1978, the growth in importance of this drug class, both financially and medically, has been staggering. The aim of this paper is to summarise how this drug class was developed, highlighting the role ofAkira Endo.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Mevastatin, ≥98% (HPLC), powder or crystals