CN
- Polymeric ethyl glyoxylate in an asymmetric aldol reaction catalyzed by diarylprolinol.
Polymeric ethyl glyoxylate in an asymmetric aldol reaction catalyzed by diarylprolinol.
Organic letters (2010-06-10)
Tatsuya Urushima, Yusuke Yasui, Hayato Ishikawa, Yujiro Hayashi
PMID20527926
ABSTRACT
Diarylprolinol was found to be an effective organocatalyst of the direct, enantioselective aldol reaction of commercially available polymeric ethyl glyoxylate, affording gamma-ethoxycarbonyl-beta-hydroxy aldehydes, versatile synthetic intermediates, in good yield with excellent enantioselectivity.
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