- Bohlmann-Rahtz cyclodehydration of aminodienones to pyridines using N-iodosuccinimide.
Bohlmann-Rahtz cyclodehydration of aminodienones to pyridines using N-iodosuccinimide.
Molecules (Basel, Switzerland) (2010-07-27)
Mark C Bagley, Christian Glover
PMID20657473
ABSTRACT
Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N-iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total regiocontrol.
MATERIALS