Merck
CN
  • Palladium-catalyzed three-component reaction of 2-alkynylbromobenzene, 2-alkynylaniline, and electrophile: an efficient pathway for the synthesis of diverse 11H-indeno[1,2-c]quinolines.

Palladium-catalyzed three-component reaction of 2-alkynylbromobenzene, 2-alkynylaniline, and electrophile: an efficient pathway for the synthesis of diverse 11H-indeno[1,2-c]quinolines.

Organic & biomolecular chemistry (2012-01-26)
Xiaolin Pan, Yong Luo, Jie Wu
ABSTRACT

Diverse 11H-indeno[1,2-c]quinolines are produced via a palladium-catalyzed three-component reaction of 2-alkynylbromobenzene, 2-alkynylaniline, and electrophile. This conversion tolerates a wide variety of functionality and substitution patterns on the 11H-indeno[1,2-c]quinoline ring.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Bromobenzene, ≥99.5% (GC)
Sigma-Aldrich
Bromobenzene, ReagentPlus®, 99%