- Novel sulphur-rich BODIPY systems that enable stepwise fluorescent O-atom turn-on and H2O2 neuronal system probing.
Novel sulphur-rich BODIPY systems that enable stepwise fluorescent O-atom turn-on and H2O2 neuronal system probing.
Chemical communications (Cambridge, England) (2012-06-16)
Atul P Singh, Kang Mun Lee, Dhiraj P Murale, Taehong Jun, Hyunjeong Liew, Yoo-Hun Suh, David G Churchill
PMID22699558
ABSTRACT
Bis-arylsulfide BODIPY systems were prepared and studied for multiple O-atom sensing (at 522 nm); 2- and 3-atom loading was optimal (50-fold, "turn on"). Neuronal studies showed greater H(2)O(2) sensitivity than 2',7'-dichlorofluorescein diacetate. The novel 1,3,6-trimethyl BODIPY formed as a biproduct under Lindsey conditions.
MATERIALS