- Two new cholic acid derivatives from the marine ascidian-associated bacterium Hasllibacter halocynthiae.
Two new cholic acid derivatives from the marine ascidian-associated bacterium Hasllibacter halocynthiae.
Molecules (Basel, Switzerland) (2012-10-24)
Sung Hun Kim, Yun Kyung Shin, Young Chang Sohn, Hak Cheol Kwon
PMID23090017
ABSTRACT
The investigation of secondary metabolites in liquid cultures of a recently discovered marine bacterium, Hasllibacter halocynthiae strain KME 002T, led to the isolation of two new cholic acid derivatives. The structures of these compounds were determined to be 3,3,12-trihydroxy-7-ketocholanic acid (1) and 3,3,12-trihydroxy-7-deoxycholanic acid (2) through HRFABMS and NMR data analyses.