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  • Excision biopsy in a patient with suspected local anaesthetic allergy: use of 0.9% saline with benzyl alcohol as local anaesthesia.

Excision biopsy in a patient with suspected local anaesthetic allergy: use of 0.9% saline with benzyl alcohol as local anaesthesia.

Clinical and experimental dermatology (2012-11-23)
V M L Jolliffe, R D Sinclair
ABSTRACT

Dermatologists may see patients with actual or suspected local anaesthetic (LA) allergy who require an urgent dermatological procedure to be performed without time for formal allergy testing. We report a case of shave biopsy and subsequent excision biopsy of an atypical naevus performed using tumescent analgesia with 0.9% saline containing benzyl alcohol preservative. The tumescence itself and the benzyl alcohol present in the 0.9% saline solution provided sufficient analgesia for excision. This technique may be an option for managing urgent procedures in patients suspected or known to have allergy to LA.

MATERIALS
Product Number
Brand
Product Description

Supelco
Benzyl alcohol, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
Benzyl alcohol, ≥99%, FCC, FG
Sigma-Aldrich
Benzyl alcohol, anhydrous, 99.8%
Sigma-Aldrich
Benzyl alcohol, natural, ≥98%, FG
Supelco
Benzyl alcohol, analytical standard
Sigma-Aldrich
Benzyl alcohol, ReagentPlus®, ≥99%
Sigma-Aldrich
Benzyl alcohol, puriss. p.a., ACS reagent, ≥99.0% (GC)
Sigma-Aldrich
Benzyl alcohol, ACS reagent, ≥99.0%
Sigma-Aldrich
Benzyl alcohol, puriss., meets analytical specification of Ph. Eur., BP, NF, 99-100.5% (GC)
Benzyl alcohol, European Pharmacopoeia (EP) Reference Standard