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  • New photoactive compounds to probe cholic acid and cholesterol inside mixed micelles.

New photoactive compounds to probe cholic acid and cholesterol inside mixed micelles.

Organic letters (2013-01-01)
Edurne Nuin, Miguel Gómez-Mendoza, Inmaculada Andreu, M Luisa Marin, Miguel A Miranda
ABSTRACT

New photoactive dyads have been synthesized by derivatization of cholic acid (CA) or cholesterol (Ch). These compounds have proven to be efficient tools to monitor incorporation of CA and Ch to mixed micelles (MM) and to probe the microenvironment experienced inside these entities. The outstanding capability of MM to solubilize Ch has been demonstrated.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Cholic acid, from bovine and/or ovine, ≥98%
Cholic acid, European Pharmacopoeia (EP) Reference Standard
Sigma-Aldrich
Cholic acid, Vetec, reagent grade, 98%