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Chemical constituents of Spatholobus suberectus.

Chinese journal of natural medicines (2013-01-11)
Ren-Neng Tang, Xiao-Bo Qu, Shu-Hong Guan, Ping-Ping Xu, Yang-Yang Shi, De-An Guo
ABSTRACT

To investigate chemical constituents of Spatholobus suberectus Dunn. Isolation and purification were carried out by column chromatographic methods. Compounds were characterized based on their physical characteristics and spectra data. Seventeen compounds were isolated from ethanol extract of S. suberectus. The structures were elucidated as prestegane B (1), (2R, 3R)-buteaspermanol (2), (+)-medioresinol (3), (2R, 3R)-3,7-dihydroxyflavanone (4), benzeneethanol (5), 4, 7, 2'-trihydroxy-4'-methoxyisoflavanol (6), naringenin (7), blumenol A (8), protocatechuic acid ethyl ester (9), liquiritigenin (10), 7, 4'-dihydroxy-8-methoxy-isoflavone (11), 3, 5, 7, 3', 5'-pentahydroxyflavanone (12), protocatechuic acid (13), glycyroside (14), 8-methylretusin-7-O-β-D-glucopyranoside (15), 3, 3', 4', 5, 6, 7, 8-heptahydroxyflavan (16), and dulcisflavan (17). All compounds are firstly isolated from the title plant and compounds 1, 3 were isolated from the Spatholobus genus for the first time.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
4-Hydroxybutanoic acid lactone, ≥98%, FCC, FG
Sigma-Aldrich
γ-Butyrolactone, ReagentPlus®, ≥99%