CN
- Direct access to enantioenriched spiroacetals through asymmetric relay catalytic three-component reaction.
Direct access to enantioenriched spiroacetals through asymmetric relay catalytic three-component reaction.
Organic letters (2013-01-15)
Hua Wu, Yu-Ping He, Liu-Zhu Gong
PMID23312017
ABSTRACT
The gold(I)/chiral Brønsted acid relay catalysis enabled a highly stereoselective three-component reaction of salicylaldehydes, anilines, and alkynols to give aromatic spiroacetals in high yields and stereoselectivities.