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  • The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD+ AML but retains in vitro sensitivity to PKC412 and Sunitinib.

The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD+ AML but retains in vitro sensitivity to PKC412 and Sunitinib.

Leukemia (2013-02-09)
C Albers, H Leischner, M Verbeek, C Yu, A L Illert, C Peschel, N von Bubnoff, J Duyster
PMID23392356
MATERIALS
Product Number
Brand
Product Description
37095
Supelco
Staurosporine, VETRANAL®, analytical standard
S5921
Sigma-Aldrich
Staurosporine from Streptomyces sp., Molecular Biology, ≥95% (HPLC)
S4400
Sigma-Aldrich
Staurosporine from Streptomyces sp., ≥98% (HPLC), film