[Radiomodifying properties of deuterium-depleted water with poor content of heavier isotopes of oxygen].

Experiments were performed with outbreed mice CD-I and hybrid mice (CBA' C57BI)F1. Seven to 21 days before irradiation, the mice had continuously consumed light-isotope water (35 ppm) produced by rectification w/o secondary treatment. Dose of single gamma-irradiation ranged from 4 to 8.5 Gy. The radiomodifying effects included statistically reliable reductions in survivability and life span, loss of body mass, and decreases in marrow myelokaryocytes and peripheral leukocytes. In 8-9 days after irradiation, spleen mass in the experimental mice was found enlarged as compared with the controls.