CN
- Remarkable effect of CF3CH2OH for the halogen induced oxidative rearrangement reaction of aminals leading to 3,4-dihydroquinazolines.
Remarkable effect of CF3CH2OH for the halogen induced oxidative rearrangement reaction of aminals leading to 3,4-dihydroquinazolines.
Organic & biomolecular chemistry (2013-03-06)
Kenichi Murai, Masato Shimura, Ryu Nagao, Daisuke Endo, Hiromichi Fujioka
PMID23460111
ABSTRACT
CF3CH2OH was found to be a useful solvent for the oxidative rearrangement reactions of aminals promoted by N-chlorosuccinimide, which proceed via the intermediacy of in situ formed chloro-aminals and that produce 3,4-dihydroquinazolines.