Merck
CN
  • Hydroxylamine analogs of 2,6-di-t-butylphenols: dual inhibitors of cyclooxygenase and 5-lipoxygenase or selective 5-lipoxygenase inhibitors.

Hydroxylamine analogs of 2,6-di-t-butylphenols: dual inhibitors of cyclooxygenase and 5-lipoxygenase or selective 5-lipoxygenase inhibitors.

Bioorganic & medicinal chemistry (1995-04-01)
J B Kramer, T Capiris, J C Sircar, D T Connor, D A Bornemeier, R D Dyer, P J Kuipers, J A Kennedy, C D Wright, G C Okonkwo
ABSTRACT

The preparation of hydroxylamine analogs of 2,6-di-tert-butylphenols (DTBP) and the inhibition of cyclooxygenase (CO) and 5-lipoxygenase (5-LO) by these compounds is discussed.